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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：P55089 New Search
6PDB entries
11Biological assembly
13chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
2RMF Human Urocortin 1 Deposited 2007-10-16 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 83–122（40 aa）
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions 298 K；Pressure ambient
NMR sample composition 1.5mM Human Ucn1, DMSO | DMSO
Resolution not provided
3N96 Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 1 Deposited 2010-05-28 Assembly 1 Other combination Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain F 107–122（16 aa） Fragment：UNP residues 107-122
Chain G 107–122（16 aa） Fragment：UNP residues 107-122
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.6；293 K；10% PEG 6000 0.1M Sodium acetate(pH 4.6) 0.1M MgCl2 14% Glycerol, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.75 Å R-free 0.273
3N96 Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 1 Deposited 2010-05-28 Assembly 10 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain H 107–122（16 aa） Fragment：UNP residues 107-122
Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.6；293 K；10% PEG 6000 0.1M Sodium acetate(pH 4.6) 0.1M MgCl2 14% Glycerol, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.75 Å R-free 0.273
3N96 Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 1 Deposited 2010-05-28 Assembly 2 Other combination Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain E 107–122（16 aa） Fragment：UNP residues 107-122
Chain H 107–122（16 aa） Fragment：UNP residues 107-122
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.6；293 K；10% PEG 6000 0.1M Sodium acetate(pH 4.6) 0.1M MgCl2 14% Glycerol, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.75 Å R-free 0.273
3N96 Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 1 Deposited 2010-05-28 Assembly 7 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain E 107–122（16 aa） Fragment：UNP residues 107-122
Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.6；293 K；10% PEG 6000 0.1M Sodium acetate(pH 4.6) 0.1M MgCl2 14% Glycerol, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.75 Å R-free 0.273
3N96 Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 1 Deposited 2010-05-28 Assembly 8 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain F 107–122（16 aa） Fragment：UNP residues 107-122
Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.6；293 K；10% PEG 6000 0.1M Sodium acetate(pH 4.6) 0.1M MgCl2 14% Glycerol, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.75 Å R-free 0.273
3N96 Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 1 Deposited 2010-05-28 Assembly 9 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain G 107–122（16 aa） Fragment：UNP residues 107-122
Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.6；293 K；10% PEG 6000 0.1M Sodium acetate(pH 4.6) 0.1M MgCl2 14% Glycerol, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.75 Å R-free 0.273
6PB0 Cryo-EM structure of Urocortin 1-bound Corticotropin-releasing factor 1 receptor in complex with Gs protein and Nb35 Deposited 2019-06-12 Assembly 1 Insufficient information Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain U 83–122（40 aa）
Not recorded CLR CHOLESTEROL × 5 PLM PALMITIC ACID × 7 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.00 Å
6PB1 Cryo-EM structure of Urocortin 1-bound Corticotropin-releasing factor 2 receptor in complex with Gs protein and Nb35 Deposited 2019-06-12 Assembly 1 Insufficient information Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain U 83–122（40 aa）
Not recorded CLR CHOLESTEROL × 4 PLM PALMITIC ACID × 5 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.80 Å
7TRY Cryo-EM structure of corticotropin releasing factor receptor 2 bound to Urocortin 1 and coupled with heterotrimeric G11 protein Deposited 2022-01-31 Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain U 83–122（40 aa） Fragment：UNP residues 83-122
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.70 Å
7TS0 Cryo-EM structure of corticotropin releasing factor receptor 2 bound to Urocortin 1 and coupled with heterotrimeric Go protein Deposited 2022-01-31 Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain U 83–122（40 aa） Fragment：UNP residues 83-122
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.80 Å

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.