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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：P61011 New Search
9PDB entries
18Biological assembly
19chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
1MFQ Crystal Structure Analysis of a Ternary S-Domain Complex of Human Signal Recognition Particle Deposited 2002-08-13 Assembly 1 Protein–RNA Heteromer；Protein × 2 PDB declaration: trimeric（3） Consistent with all polymers
Chain C 323–441（119 aa） Fragment：M-domain
Not recorded MG MAGNESIUM ION × 5 CL CHLORIDE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；300.5 K；14% (w/v) PEG8000, 100mM Na-cacodylate, 400mM lithium sulfate, 80mM magnesium chloride, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 300.5K
Resolution 3.10 Å R-free 0.267
1QB2 CRYSTAL STRUCTURE OF THE CONSERVED SUBDOMAIN OF HUMAN PROTEIN SRP54M AT 2.1A RESOLUTION: EVIDENCE FOR THE MECHANISM OF SIGNAL PEPTIDE BINDING Deposited 1999-04-29 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 326–434（109 aa） Fragment：SRP54
Chain B 326–434（109 aa） Fragment：SRP54
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.6；277 K；30% PEG 2K, pH 4.6, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 2.10 Å R-free 0.318
5L3Q Structure of the GTPase heterodimer of human SRP54 and SRalpha Deposited 2016-05-24 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–436（436 aa）
Not recorded SO4 SULFATE ION × 5 GNP PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER × 2 MG MAGNESIUM ION × 2 GOL GLYCEROL × 2 AMP ADENOSINE MONOPHOSPHATE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；277 K；100 mM Tris pH 8.0, 400 mM lithium sulfate, 10 % (w/v) PEG 8000
Resolution 3.20 Å R-free 0.191
5L3Q Structure of the GTPase heterodimer of human SRP54 and SRalpha Deposited 2016-05-24 Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain C 1–436（436 aa）
Not recorded SO4 SULFATE ION × 4 GNP PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER × 2 MG MAGNESIUM ION × 2 GOL GLYCEROL × 2 AMP ADENOSINE MONOPHOSPHATE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；277 K；100 mM Tris pH 8.0, 400 mM lithium sulfate, 10 % (w/v) PEG 8000
Resolution 3.20 Å R-free 0.191
6Y2Z NG domain of human SRP54 Deposited 2020-02-17 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–296（296 aa）
Not recorded PO4 PHOSPHATE ION × 1 MG MAGNESIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；291.15 K；na2hpo4 0.8 M K2HPO4 0.8 M HEPES 0.1 M (pH 7.5)
Resolution 2.15 Å R-free 0.246
6Y2Z NG domain of human SRP54 Deposited 2020-02-17 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 1–296（296 aa）
Not recorded PO4 PHOSPHATE ION × 1 MG MAGNESIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；291.15 K；na2hpo4 0.8 M K2HPO4 0.8 M HEPES 0.1 M (pH 7.5)
Resolution 2.15 Å R-free 0.246
6Y30 NG domain of human SRP54 T115A mutant Deposited 2020-02-17 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–296（296 aa）
Mutation：T115A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；291.15 K；1M Potassium Citrate
Resolution 2.65 Å R-free 0.309
6Y30 NG domain of human SRP54 T115A mutant Deposited 2020-02-17 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 1–296（296 aa）
Mutation：T115A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；291.15 K；1M Potassium Citrate
Resolution 2.65 Å R-free 0.309
6Y31 NG domain of human SRP54 T117 deletion mutant Deposited 2020-02-17 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–296（296 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；291.15 K；0.8 M Na2HPO4 , 0.8 M K2HPO4 HEPES 0.1 M (pH 7.5)
Resolution 4.00 Å R-free 0.331
6Y31 NG domain of human SRP54 T117 deletion mutant Deposited 2020-02-17 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 1–296（296 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；291.15 K；0.8 M Na2HPO4 , 0.8 M K2HPO4 HEPES 0.1 M (pH 7.5)
Resolution 4.00 Å R-free 0.331
6Y31 NG domain of human SRP54 T117 deletion mutant Deposited 2020-02-17 Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain C 1–296（296 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；291.15 K；0.8 M Na2HPO4 , 0.8 M K2HPO4 HEPES 0.1 M (pH 7.5)
Resolution 4.00 Å R-free 0.331
6Y31 NG domain of human SRP54 T117 deletion mutant Deposited 2020-02-17 Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain D 1–296（296 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；291.15 K；0.8 M Na2HPO4 , 0.8 M K2HPO4 HEPES 0.1 M (pH 7.5)
Resolution 4.00 Å R-free 0.331
6Y32 Structure of the GTPase heterodimer of human SRP54 and SRalpha Deposited 2020-02-17 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–296（296 aa）
Not recorded GNP PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER × 2 MG MAGNESIUM ION × 2 SO4 SULFATE ION × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；291.15 K；0.4 M lithium sulfate, 13% (w/v) PEG 3350, 0.1 M Tris (pH 8.0)
Resolution 2.60 Å R-free 0.184
6Y32 Structure of the GTPase heterodimer of human SRP54 and SRalpha Deposited 2020-02-17 Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain C 1–296（296 aa）
Not recorded GNP PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER × 2 MG MAGNESIUM ION × 2 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；291.15 K；0.4 M lithium sulfate, 13% (w/v) PEG 3350, 0.1 M Tris (pH 8.0)
Resolution 2.60 Å R-free 0.184
6Y32 Structure of the GTPase heterodimer of human SRP54 and SRalpha Deposited 2020-02-17 Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain E 1–296（296 aa）
Not recorded GNP PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER × 2 MG MAGNESIUM ION × 2 SO4 SULFATE ION × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；291.15 K；0.4 M lithium sulfate, 13% (w/v) PEG 3350, 0.1 M Tris (pH 8.0)
Resolution 2.60 Å R-free 0.184
6Y32 Structure of the GTPase heterodimer of human SRP54 and SRalpha Deposited 2020-02-17 Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain G 1–296（296 aa）
Not recorded GNP PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER × 2 MG MAGNESIUM ION × 2 SO4 SULFATE ION × 6 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；291.15 K；0.4 M lithium sulfate, 13% (w/v) PEG 3350, 0.1 M Tris (pH 8.0)
Resolution 2.60 Å R-free 0.184
7NFX Mammalian ribosome nascent chain complex with SRP and SRP receptor in early state A Deposited 2021-02-08 Assembly 1 Protein–RNA Heteromer；Protein × 51 PDB declaration: 55-meric（55） Consistent with all polymers
Chain x 1–504（504 aa）
Not recorded ZN ZINC ION × 5 MG MAGNESIUM ION × 2 GTP GUANOSINE-5'-TRIPHOSPHATE × 1 GNP PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE-PROPANE
Resolution 3.20 Å
7QWQ Ternary complex of ribosome nascent chain with SRP and NAC Deposited 2022-01-25 Assembly 1 Protein–RNA Heteromer；Protein × 48 PDB declaration: 52-meric（52） Consistent with all polymers
Chain x 1–504（504 aa）
Not recorded MG MAGNESIUM ION × 97 ZN ZINC ION × 5 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE-PROPANE
Resolution 2.83 Å

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.