Current Protein Identity:P62068
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 5CVM USP46~ubiquitin BEA covalent complex Deposited 2015-07-27 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
25–366(342 aa)
Fragment:UNP residues 25-366
|
Not recorded | ZN ZINC ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;292 K;3.6 M sodium formate
|
Resolution 1.90 Å R-free 0.197 |
| 5CVN WDR48 (2-580):USP46~ubiquitin ternary complex Deposited 2015-07-27 | Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain B
25–366(342 aa)
Fragment:UNP residues 25-366
|
Not recorded | ZN ZINC ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 8.8;292 K;0.1 M sodium chloride, 5% ethanol, 15% MPD, 0.1 M Tris pH 8.8
|
Resolution 3.36 Å R-free 0.222 |
| 5CVO WDR48:USP46~ubiquitin ternary complex Deposited 2015-07-27 | Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain B
25–366(342 aa)
Fragment:UNP residues 25-366
|
Not recorded | ZN ZINC ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7;292 K;15% MPD, 0.1 M NaCl, 0.1 M HEPES, pH 7.0
|
Resolution 3.88 Å R-free 0.275 |
| 5CVO WDR48:USP46~ubiquitin ternary complex Deposited 2015-07-27 | Assembly 2 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain E
25–366(342 aa)
Fragment:UNP residues 25-366
|
Not recorded | ZN ZINC ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7;292 K;15% MPD, 0.1 M NaCl, 0.1 M HEPES, pH 7.0
|
Resolution 3.88 Å R-free 0.275 |
| 5L8H Structure of USP46-UbVME Deposited 2016-06-07 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
8–366(359 aa)
|
Not recorded | ZN ZINC ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7.5;293 K;0.96M Sodium Citrate pH7.5 and 0.1mM zinc chloride
Cryo - 20% Glycerol
|
Resolution 1.85 Å R-free 0.194 |
| 6JLQ Crystal structure of human USP46-WDR48-WDR20 complex Deposited 2019-03-06 | Assembly 1 Insufficient information Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain A
24–366(343 aa)
|
Not recorded | ZN ZINC ION × 1 GOL GLYCEROL × 8 PO4 PHOSPHATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;289 K;1.0M Sodium phosphate monobasic monohydrate, Potassium phosphate dibasic, pH 7.2
|
Resolution 3.10 Å R-free 0.272 |