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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：P62992 New Search
15PDB entries
17Biological assembly
27chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
4M0W Crystal Structure of SARS-CoV papain-like protease C112S mutant in complex with ubiquitin Deposited 2013-08-02 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 1–76（76 aa）
Not recorded ZN ZINC ION × 1 NA SODIUM ION × 1 NHE 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID × 2 GOL GLYCEROL × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 9.5；295 K；18% PEG 3000, 0.1M CHES, pH 9.5, VAPOR DIFFUSION, SITTING DROP, temperature 295K
Resolution 1.40 Å R-free 0.180
4Y1H Crystal structure of K33 linked tri-Ubiquitin Deposited 2015-02-07 Assembly 1 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 1–76（76 aa）
Not recorded EDO 1,2-ETHANEDIOL × 12 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；293 K；100mM Bis Tris propane (pH 7.5), 20mM sodium/potassium phosphate, 20% PEG3350
Resolution 1.40 Å R-free 0.194
4Z9S Non-covalent assembly of monoubiquitin that mimics K11 poly-ubiquitin Deposited 2015-04-11 Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 1–76（76 aa） Fragment：UNP RESIDUES 1-76
Chain B 1–76（76 aa） Fragment：UNP RESIDUES 1-76
Chain C 1–76（76 aa） Fragment：UNP RESIDUES 1-76
Chain D 1–76（76 aa） Fragment：UNP RESIDUES 1-76
Not recorded MLA MALONIC ACID × 6 SCN THIOCYANATE ION × 9 X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 4；292 K；3.4M SODIUM MALONATE, 0.1 M SODIUM THIOSUCCINATE PH4.0, VAPOR DIFFUSION, SITTING DROP, TEMPERATURE 292K
Resolution 2.30 Å R-free 0.223
5BZ0 Crystal structure of IBV papain-like protease PLpro C101S mutant in complex with ubiquitin Deposited 2015-06-11 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 1–76（76 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；291 K；0.1 M HEPES pH 7.5, 20% w/v Polyethylene glycol 10,000.
Resolution 2.10 Å R-free 0.228
5FER Complex of TRIM25 RING with UbcH5-Ub Deposited 2015-12-17 Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain C 1–76（76 aa）
Chain F 1–76（76 aa）
Not recorded ZN ZINC ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；291 K；10% PEG 20000 and 100 mM Tris pH 8.5
Resolution 2.34 Å R-free 0.273
5JQS Crystal structure of deubiquitinase MINDY-1 in complex with Ubiquitin Deposited 2016-05-05 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain D 1–76（76 aa）
Not recorded AYE prop-2-en-1-amine × 1 SO4 SULFATE ION × 3 CL CHLORIDE ION × 1 DIO 1,4-DIETHYLENE DIOXIDE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；293.15 K；100mM MES, 10% Dioxane and 1.6 M ammonium sulphate
Resolution 2.65 Å R-free 0.231
5MN9 Crystal structure of MINDY-1 tMIU in complex with K48-diUb Deposited 2016-12-13 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 1–76（76 aa）
Chain B 1–76（76 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.4；293.15 K；100 mM sodium acetate pH 5.4 and 18.5 % PEG3350
Resolution 2.05 Å R-free 0.223
5XU8 Crystal structure of human USP2 in complex with ubiquitin and 6-thioguanine Deposited 2017-06-22 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 1–76（76 aa） Fragment：UNP residues 1-76
Not recorded DX4 2-amino-1,9-dihydro-6H-purine-6-thione × 1 ZN ZINC ION × 1 CL CHLORIDE ION × 5 NA SODIUM ION × 5 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；295 K；24.5% PEG3350, 0.2 M MgC12, 0.1 M Bis-Tris
Resolution 1.81 Å R-free 0.238
5XVE Crystal structure of human USP2 C276S mutant in complex with ubiquitin Deposited 2017-06-27 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 1–76（76 aa） Fragment：UNP residues 1-76
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8；295 K；21% PEG3350, 8% Tacsimate (pH8.0)
Resolution 1.24 Å R-free 0.164
6DJW Crystal Structure of pParkin (REP and RING2 deleted)-pUb-UbcH7 complex Deposited 2018-05-26 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain B 1–74（74 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) ZN ZINC ION × 6 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；277 K；0.1 M Tris-HCl, pH 8.0, 15% w/v PEG2000 MME, 0.1 M potasssium chloride
Resolution 3.80 Å R-free 0.297
6DJX Crystal Structure of pParkin-pUb-UbcH7 complex Deposited 2018-05-27 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain B 1–76（76 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) ZN ZINC ION × 6 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；277 K；0.1 M HEPES, pH 6.5, 6% isopropanol, 50 mM magnesium chloride, 5% w/v PEG4000
Resolution 4.80 Å R-free 0.290
6E2B Ubiquitin in complex with Pt(2-phenilpyridine)(PPh3) Deposited 2018-07-11 Assembly 1 Protein homooligomer Homooligomer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain A 1–76（76 aa）
Chain C 1–76（76 aa）
Chain E 1–76（76 aa）
Chain G 1–76（76 aa）
Chain I 1–76（76 aa）
Chain P 1–76（76 aa）
Not recorded SO4 SULFATE ION × 6 GOL GLYCEROL × 8 PT7 chloro[2-(pyridin-2-yl-kappaN)phenyl-kappaC~1~](triphenyl-lambda~5~-phosphanyl)platinum(2+) × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.5；289 K；3M ammonium sulfate, 0.1M sodium citrate buffer, pH 5.5
Resolution 1.45 Å R-free 0.207
6Q01 TDP2 UBA Domain Bound to Ubiquitin at 0.85 Angstroms Resolution, Crystal Form 2 Deposited 2019-08-01 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–76（76 aa）
Not recorded MG MAGNESIUM ION × 2 EDO 1,2-ETHANEDIOL × 1 K POTASSIUM ION × 2 BEZ BENZOIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；277 K；20 mM TRIS pH 7.5, 100 mM NaCl, 150 mM Magnesium Formate, 200 mM Potassium Formate, 18% (w/v) PEG 3350
Resolution 0.85 Å R-free 0.114
6Q01 TDP2 UBA Domain Bound to Ubiquitin at 0.85 Angstroms Resolution, Crystal Form 2 Deposited 2019-08-01 Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 1–76（76 aa）
Not recorded K POTASSIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；277 K；20 mM TRIS pH 7.5, 100 mM NaCl, 150 mM Magnesium Formate, 200 mM Potassium Formate, 18% (w/v) PEG 3350
Resolution 0.85 Å R-free 0.114
7F0U porcine epidemic diarrhea virus papain-like protease 2 C44S mutant in complex with mono ubiquitin Deposited 2021-06-07 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain C 1–76（76 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8；295 K；19% PEG-3350, 50 mM HEPES pH 8.0 and 1% w/v tryptone
Resolution 2.20 Å R-free 0.260
7F0U porcine epidemic diarrhea virus papain-like protease 2 C44S mutant in complex with mono ubiquitin Deposited 2021-06-07 Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain D 1–76（76 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8；295 K；19% PEG-3350, 50 mM HEPES pH 8.0 and 1% w/v tryptone
Resolution 2.20 Å R-free 0.260
7NWH Mammalian pre-termination 80S ribosome with eRF1 and eRF3 bound by Blasticidin S. Deposited 2021-03-16 Assembly 1 Protein–RNA Heteromer；Protein × 79 PDB declaration: 84-meric（84） Consistent with all polymers
Chain ff 83–150（68 aa）
Not recorded ZN ZINC ION × 8 MG MAGNESIUM ION × 281 GCP PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER × 1 BLS BLASTICIDIN S × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4；50 mM HEPES pH 7.4 100 mM KOAc 5 mM Mg(Oac)2 1mM DTT
cryo-EM vitrification conditions Cryogen ETHANE；30s sample incubation on grid followed by 1.1s blotting time.
Resolution 4.10 Å

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.