Current Protein Identity:P63241
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 3CPF Crystal structure of human eukaryotic translation initiation factor EIF5A Deposited 2008-03-31 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
15–151(137 aa)
Fragment:Residues 15-151
|
Not recorded | UNX UNKNOWN LIGAND × 6 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 5.5;291 K;22% PEG 3350, 0.2M Ammonium sulfate, 0.1M Sodium cacodylate. Cryoprotected with 20% PEG 3350 and 20% Ethylene glycol, pH 5.5, VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 2.50 Å R-free 0.300 |
| 3CPF Crystal structure of human eukaryotic translation initiation factor EIF5A Deposited 2008-03-31 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
15–151(137 aa)
Fragment:Residues 15-151
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 5.5;291 K;22% PEG 3350, 0.2M Ammonium sulfate, 0.1M Sodium cacodylate. Cryoprotected with 20% PEG 3350 and 20% Ethylene glycol, pH 5.5, VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 2.50 Å R-free 0.300 |
| 5DLQ Crystal structure of RanGTP-Exportin 4-eIF5A complex Deposited 2015-09-07 | Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain F
45–184(140 aa)
|
Non-standard monomer:Yes (specific site not provided by mmCIF) | GTP GUANOSINE-5'-TRIPHOSPHATE × 1 MG MAGNESIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.26;293 K;Peg 400, MES
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.26;293 K;Peg 400, MES, DTT
|
Resolution 3.20 Å R-free 0.270 |
| 5DLQ Crystal structure of RanGTP-Exportin 4-eIF5A complex Deposited 2015-09-07 | Assembly 2 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain E
45–184(140 aa)
|
Non-standard monomer:Yes (specific site not provided by mmCIF) | GTP GUANOSINE-5'-TRIPHOSPHATE × 1 MG MAGNESIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.26;293 K;Peg 400, MES
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.26;293 K;Peg 400, MES, DTT
|
Resolution 3.20 Å R-free 0.270 |
| 8Y0W dormant ribosome with eIF5A, eEF2 and SERBP1 Deposited 2024-01-23 | Assembly 1 Protein–RNA Heteromer;Protein × 77 PDB declaration: 81-meric(81) Consistent with all polymers |
Chain 5
1–154(154 aa)
|
Not recorded | MG MAGNESIUM ION × 226 ZN ZINC ION × 5 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5;50mM HEPES, pH7.5, 100mM KOAc, 5mM Mg(OAc)2, 1mM DTT
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.40 Å |