Current Protein Identity:P80424
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1AN1 LEECH-DERIVED TRYPTASE INHIBITOR/TRYPSIN COMPLEX Deposited 1997-06-26 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain I
1–46(46 aa)
|
Mutation:N115D (D-ASPARTIC ACID FORM) | CA CALCIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 8.5;30% V/V 2-PROPANOL, 0.2M AMMONIUM ACETATE, 0.1M TRIS-HCL, PH 8.5 ROOM TEMPERATURE 27 MONTHS FOR GROWTH.
|
Resolution 2.03 Å R-free 0.228 |
| 1LDT COMPLEX OF LEECH-DERIVED TRYPTASE INHIBITOR WITH PORCINE TRYPSIN Deposited 1997-05-15 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain L
1–46(46 aa)
|
Not recorded | CA CALCIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 8;10% PEG 6000, 2.3M PHOSPHATE, PH 8.0
|
Resolution 1.90 Å |
| 2KMO Solution structure of native Leech-derived tryptase inhibitor, LDTI Deposited 2009-08-03 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
1–44(44 aa)
Fragment:residues 1-44
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 1.7;298 K;Pressure ambient
NMR sample composition
1.7 mM LDTI, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
1.7 mM LDTI, 100% D2O | 100% D2O
|
Resolution not provided |
| 2KMP Solution structure of intermeidate IIa of Leeck-derived tryptase inhibitor, LDTI. Deposited 2009-08-03 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
1–44(44 aa)
Fragment:residues 1-44
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 1.7;298 K;Pressure ambient
NMR sample composition
1.7 mM LDTI, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
1.7 mM LDTI, 100% D2O | 100% D2O
|
Resolution not provided |
| 2KMQ Solution structure of intermediate IIb of Leech-derived tryptase inhibitor, LDTI. Deposited 2009-08-03 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
1–44(44 aa)
Fragment:residues 1-44
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 1.7;298 K;Pressure ambient
NMR sample composition
1.7 mM LDTI-IIb, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
1.7 mM LDTI-IIb, 100% D2O | 100% D2O
|
Resolution not provided |
| 2KMR Solution structure of intermediate IIc of Leech-derived tryptase inhibitor, LDTI. Deposited 2009-08-03 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
1–44(44 aa)
Fragment:residues 1-44
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 1.7;298 K;Pressure ambient
NMR sample composition
1.7 mM LDTI-IIc, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
1.7 mM LDTI-IIc, 100% D2O | 100% D2O
|
Resolution not provided |