Current Protein Identity：P83476
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 2N9T NMR solution structure of ProTx-II Deposited 2015-12-08 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–30（30 aa）
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
298 K；Pressure ambient
NMR sample composition
2 mg protein, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
2 mg protein, 100% D2O | 100% D2O
|
Resolution not provided |
| 5O0U Crystal structure of tarantula venom peptide Protoxin-II Deposited 2017-05-17 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–30（30 aa）
|
Not recorded | CL CHLORIDE ION × 2 EDO 1,2-ETHANEDIOL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；2M lithium sulfate, 100 mM Tris-HCl (pH 8), 2% v/v PEG 400
|
Resolution 0.99 Å R-free 0.140 |
| 6MK4 Solution NMR structure of spider toxin analogue [E17K]ProTx-II Deposited 2018-09-25 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–30（30 aa）
|
Mutation：E17K | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
298 K；Ionic strength (raw mmCIF value) 0；Pressure 1
NMR measurement conditions
298 K；Ionic strength (raw mmCIF value) 0；Pressure 1
NMR sample composition
2 mg/mL [E17K]ProTx-II, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 6N4I Structural basis of Nav1.7 inhibition by a gating-modifier spider toxin Deposited 2018-11-19 | Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count |
Chain E
1–30（30 aa）
Chain F
1–30（30 aa）
Chain G
1–30（30 aa）
Chain H
1–30（30 aa）
|
Not recorded | 6OU [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate × 16 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；292 K；2.3-2.6M Ammonium sulfate, 100 mM HEPES, pH 7.0; 30% sucrose for cryo
|
Resolution 3.54 Å R-free 0.294 |
| 6N4Q CryoEM structure of Nav1.7 VSD2 (actived state) in complex with the gating modifier toxin ProTx2 Deposited 2018-11-20 | Assembly 1 Insufficient information Heteromer；Protein × 12 PDB declaration: dodecameric（12） Consistent with protein count |
Chain E
1–30（30 aa）
Chain F
1–30（30 aa）
Chain G
1–30（30 aa）
Chain H
1–30（30 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8；10 mM Tris pH 8.0, 100 mM NaCl, 0.06% FA3, 0.1 mg/ml POPC:POPE:POPG mixed at molar ratio 3:1:1
cryo-EM vitrification conditions
Cryogen ETHANE；Apply 3 uL, blot 2.5s. Ted Pella 595 filter paper.
|
Resolution 3.60 Å |
| 6N4R CryoEM structure of Nav1.7 VSD2 (deactived state) in complex with the gating modifier toxin ProTx2 Deposited 2018-11-20 | Assembly 1 Insufficient information Heteromer；Protein × 12 PDB declaration: dodecameric（12） Consistent with protein count |
Chain E
1–30（30 aa）
Chain F
1–30（30 aa）
Chain G
1–30（30 aa）
Chain H
1–30（30 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8；10 mM Tris pH 8.0, 100 mM NaCl, 0.06% FA3, 0.1 mg/ml POPC:POPE:POPG mixed at molar ratio 3:1:1
cryo-EM vitrification conditions
Cryogen ETHANE；Apply 3 uL, blot 2.5s. Ted Pella 595 filter paper.
|
Resolution 4.20 Å |