Current Protein Identity：P97924
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1U3O Solution structure of rat Kalirin N-terminal SH3 domain Deposited 2004-07-22 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1637–1706（70 aa）
Fragment：SH3 domain
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 6.4；298 K；Ionic strength (raw mmCIF value) 200 mM；Pressure ambient
NMR sample composition
0.4 mM U-15N protein, 50 mM HEPES, 150 mM NaCl, 1 mM dithiotheitol, 92.5% H2O, 7.5% D2O | 92.5% H2O, 7.5% D2O
NMR sample composition
1 mM U-15N,13C protein, 50 mM HEPES, 150 mM NaCl, 1 mM dithiotheitol, 92.5% H2O, 7.5% D2O | 92.5% H2O, 7.5% D2O
|
Resolution not provided |
| 2KR9 Kalirin DH1 NMR structure Deposited 2009-12-10 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1253–1432（180 aa）
Fragment：DH 1 domain
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 6.8；298.15 K；Ionic strength (raw mmCIF value) 0.05；Pressure 1.00
NMR sample composition
0.6 mM [U-100% 13C; U-100% 15N] KalDH1, 50.0 mM Hepes, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
0.56 mM [U-100% 15N] KalDH1, 50.00 mM Hepes, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 5O33 A structure of the GEF Kalirin DH1 domain in complex with the small GTPase Rac1 Deposited 2017-05-23 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
1253–1432（180 aa）
Fragment：UNP residues 1253-1432
|
Not recorded | EDO 1,2-ETHANEDIOL × 6 GDP GUANOSINE-5'-DIPHOSPHATE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4.2；293 K；0.1M citrate pH4.2, 0.2M sodium chloride, 18% (W/V) PEG 8000
|
Resolution 1.64 Å R-free 0.240 |
| 9HU8 Crystal structure of Kalirin/Rac1 in complex with MC-278. Deposited 2024-12-20 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
1253–1432（180 aa）
|
Not recorded | A1IXV 2-chloranyl-~{N}-(2-oxidanylidene-5,6,7,8-tetrahydro-1~{H}-1,8-naphthyridin-4-yl)ethanamide × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；0.1 M citrate pH 4.2, 0.2 M NaCl and 18 % PEG 8K
|
Resolution 1.48 Å R-free 0.231 |
| 9I1L Crystal structure of Kalirin/Rac1 in complex with RS-009 Deposited 2025-01-16 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
1253–1432（180 aa）
Fragment：UNP residues 1253-1432
|
Not recorded | A1IZQ 2-chloranyl-~{N}-(6-oxidanylidene-1,7-dihydropyrrolo[2,3-b]pyridin-4-yl)ethanamide × 1 DMS DIMETHYL SULFOXIDE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；277 K；0.1 M bis-tris pH 5.5, 0.1 M NaCl,
27% PEG 3350
|
Resolution 1.68 Å R-free 0.269 |
| 9IFK Crystal structure of Kalirin/Rac1 in complex with DK-2 Deposited 2025-02-18 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
1253–1432（180 aa）
Fragment：UNP residues 1253-1432
|
Not recorded | A1I32 2-chloranyl-~{N}-(2-oxidanylidene-1~{H}-quinolin-4-yl)ethanamide × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；277 K；0.1 M citrate pH 4.7, 0.8 M LiCl and
25% PEG 6K.
|
Resolution 1.34 Å R-free 0.235 |
| 9IG1 Crystal structure of Kalirin/Rac1 in complex with DK-652 Deposited 2025-02-18 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
1253–1432（180 aa）
Fragment：UNP residues 1253-1432
|
Not recorded | A1I33 2-chloranyl-~{N}-(1-oxidanylidene-2~{H}-isoquinolin-7-yl)ethanamide × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；277 K；0.1 M bis-tris pH 5.5, 0.2 M NaCl and
25% PEG 3350
|
Resolution 1.65 Å R-free 0.293 |