Current Protein Identity：Q00653
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1A3Q HUMAN NF-KAPPA-B P52 BOUND TO DNA Deposited 1998-01-23 | Assembly 1 Protein–DNA Homooligomer；Protein × 2 PDB declaration: tetrameric（4） Consistent with all polymers |
Chain A
37–327（291 aa）
Chain B
37–327（291 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6；THE PROTEIN-DNA COMPLEX WAS CRYSTALLIZED USING THE HANGING DROP METHOD. THE RESERVOIR SOLUTION CONTAINED 5% PEG 4000, 5 MM MGSO4, 50 MM MES PH 6.0 AND 3 MM DTT. DROPS CONTAINED A 1:1 MIXTURE OF COMPLEX SOLUTION AND RESERVOIR SOLUTION., vapor diffusion - hanging drop
|
Resolution 2.10 Å R-free 0.320 |
| 2D96 Solution structure of the Death domain of Nuclear factor NF-kappa-B p100 Deposited 2005-12-08 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
766–861（96 aa）
Fragment：death domain
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7；298 K；Ionic strength (raw mmCIF value) 120mM；Pressure ambient
NMR sample composition
1.15mM death domain U-15N, 13C, 20mM TrisHCl, 100mM NaCl, 1mM DTT, 0.02% NaN3 | 90% H2O/10% D2O
|
Resolution not provided |
| 3DO7 X-ray structure of a NF-kB p52/RelB/DNA complex Deposited 2008-07-03 | Assembly 1 Protein–DNA Heteromer；Protein × 2 PDB declaration: tetrameric（4） Consistent with all polymers |
Chain B
37–329（293 aa）
Fragment：RHR (UNP residues 37-329)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；291 K；6% PEG 4000, 50 mM NaCl, 0.1% BOG, 10 mM DTT, 10 mM NaCitrate and 2 mM Spermidine, VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 3.05 Å R-free 0.273 |
| 4OT9 crystal structure of the C-terminal domain of p100/NF-kB2 Deposited 2014-02-13 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
407–765（359 aa）
|
Not recorded | SO4 SULFATE ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；291 K；10% PEG 4000, pH 7, VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 3.35 Å R-free 0.272 |
| 4OT9 crystal structure of the C-terminal domain of p100/NF-kB2 Deposited 2014-02-13 | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
407–765（359 aa）
|
Not recorded | SO4 SULFATE ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；291 K；10% PEG 4000, pH 7, VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 3.35 Å R-free 0.272 |
| 5ZMC Structural Basis for Reactivation of -146C>T Mutant TERT Promoter by cooperative binding of p52 and ETS1/2 Deposited 2018-04-02 | Assembly 1 Protein–DNA Heteromer；Protein × 2 PDB declaration: tetrameric（4） Consistent with all polymers |
Chain A
35–329（295 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；290 K；0.1 M HEPES pH 7.0 and 2.0 M Ammonium sulphate
|
Resolution 2.99 Å R-free 0.288 |
| 7CLI Structure of NF-kB p52 homodimer bound to P-Selectin kB DNA fragment Deposited 2020-07-21 | Assembly 1 Protein–DNA Homooligomer；Protein × 2 PDB declaration: tetrameric（4） Consistent with all polymers |
Chain A
1–398（398 aa）
Chain B
1–398（398 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION；293 K；0.1M Sodium malonate, pH 4.0, 0.2M CsCl, 5% PEG 3350
|
Resolution 3.00 Å R-free 0.275 |
| 7VUP Structure of NF-kB p52 homodimer bound to +1/-1 swap P-Selectin kB DNA fragment Deposited 2021-11-04 | Assembly 1 Protein–DNA Homooligomer；Protein × 2 PDB declaration: tetrameric（4） Consistent with all polymers |
Chain A
1–398（398 aa）
Chain B
1–398（398 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；0.1M Sodium malonate, pH 4.0, 50mM CsCl, 2.5% PEG 3350
|
Resolution 3.40 Å R-free 0.286 |
| 7VUQ Structure of NF-kB p52 homodimer bound to A/T-centric P-Selectin kB DNA fragment Deposited 2021-11-04 | Assembly 1 Protein–DNA Homooligomer；Protein × 2 PDB declaration: tetrameric（4） Consistent with all polymers |
Chain A
1–398（398 aa）
Chain B
1–398（398 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；0.1M Sodium malonate, pH 4.0, 50mM CsCl, 2.5% PEG 3350
|
Resolution 3.10 Å R-free 0.249 |
| 7W7L Structure of NF-kB p52 homodimer bound to 13-mer A/T-centric P-Selectin kB DNA fragment Deposited 2021-12-05 | Assembly 1 Protein–DNA Homooligomer；Protein × 2 PDB declaration: tetrameric（4） Consistent with all polymers |
Chain A
1–327（327 aa）
Chain B
1–327（327 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6；293 K；50mM MES, pH 6.0, 10mM MgCl2, 10% PEG 3350
|
Resolution 3.00 Å R-free 0.258 |