Current Protein Identity:Q0KKI6 New Search
Main Difference Dimensions in This Set
Different construct Different assembly state Different ligand/ion Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
5VZX Crystal structure of crenezumab Fab Deposited 2017-05-29 Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count
Chain I 110–219(110 aa)
Chain L 110–219(110 aa)
Not recorded SO4 SULFATE ION × 11 MES 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 2 EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;293 K;2.4 M ammonium sulfate, 0.1M HEPES pH 7.5
Resolution 2.50 Å R-free 0.230
5VZX Crystal structure of crenezumab Fab Deposited 2017-05-29 Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain L 110–219(110 aa)
Not recorded SO4 SULFATE ION × 6 MES 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 1 EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;293 K;2.4 M ammonium sulfate, 0.1M HEPES pH 7.5
Resolution 2.50 Å R-free 0.230
5VZX Crystal structure of crenezumab Fab Deposited 2017-05-29 Assembly 3 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain I 110–219(110 aa)
Not recorded SO4 SULFATE ION × 5 MES 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 1 EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;293 K;2.4 M ammonium sulfate, 0.1M HEPES pH 7.5
Resolution 2.50 Å R-free 0.230
5VZY Crystal structure of crenezumab Fab in complex with Abeta Deposited 2017-05-29 Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain L 110–219(110 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;277 K;0.2 M magnesium chloride hexahydrate, 0.1 M Tris hydrochloride pH 8.5, 30% w/v polyethylene glycol 4000
Resolution 2.32 Å R-free 0.249
5W1M MACV GP1 CR1-07 Fab complex Deposited 2017-06-03 Assembly 1 Other combination Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain A 112–218(107 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions BATCH MODE;pH 5.5;297 K;1.8 M AmSO4 and 100 mM NaCitrate pH 5.5.
Resolution 3.91 Å R-free 0.264
5W1M MACV GP1 CR1-07 Fab complex Deposited 2017-06-03 Assembly 2 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain C 112–218(107 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 X-RAY DIFFRACTION
X-ray crystallization conditions BATCH MODE;pH 5.5;297 K;1.8 M AmSO4 and 100 mM NaCitrate pH 5.5.
Resolution 3.91 Å R-free 0.264
5W1M MACV GP1 CR1-07 Fab complex Deposited 2017-06-03 Assembly 3 Other combination Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain E 112–218(107 aa)
Not recorded BMA beta-D-mannopyranose × 1 X-RAY DIFFRACTION
X-ray crystallization conditions BATCH MODE;pH 5.5;297 K;1.8 M AmSO4 and 100 mM NaCitrate pH 5.5.
Resolution 3.91 Å R-free 0.264
5W1M MACV GP1 CR1-07 Fab complex Deposited 2017-06-03 Assembly 4 Other combination Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain G 112–218(107 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions BATCH MODE;pH 5.5;297 K;1.8 M AmSO4 and 100 mM NaCitrate pH 5.5.
Resolution 3.91 Å R-free 0.264