Current Protein Identity:Q0KKI6
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 5VZX Crystal structure of crenezumab Fab Deposited 2017-05-29 | Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain I
110–219(110 aa)
Chain L
110–219(110 aa)
|
Not recorded | SO4 SULFATE ION × 11 MES 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 2 EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;293 K;2.4 M ammonium sulfate, 0.1M HEPES pH 7.5
|
Resolution 2.50 Å R-free 0.230 |
| 5VZX Crystal structure of crenezumab Fab Deposited 2017-05-29 | Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain L
110–219(110 aa)
|
Not recorded | SO4 SULFATE ION × 6 MES 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 1 EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;293 K;2.4 M ammonium sulfate, 0.1M HEPES pH 7.5
|
Resolution 2.50 Å R-free 0.230 |
| 5VZX Crystal structure of crenezumab Fab Deposited 2017-05-29 | Assembly 3 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain I
110–219(110 aa)
|
Not recorded | SO4 SULFATE ION × 5 MES 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 1 EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;293 K;2.4 M ammonium sulfate, 0.1M HEPES pH 7.5
|
Resolution 2.50 Å R-free 0.230 |
| 5VZY Crystal structure of crenezumab Fab in complex with Abeta Deposited 2017-05-29 | Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain L
110–219(110 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;277 K;0.2 M magnesium chloride hexahydrate, 0.1 M Tris hydrochloride pH 8.5, 30% w/v polyethylene glycol 4000
|
Resolution 2.32 Å R-free 0.249 |
| 5W1M MACV GP1 CR1-07 Fab complex Deposited 2017-06-03 | Assembly 1 Other combination Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain A
112–218(107 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
BATCH MODE;pH 5.5;297 K;1.8 M AmSO4 and 100 mM NaCitrate pH 5.5.
|
Resolution 3.91 Å R-free 0.264 |
| 5W1M MACV GP1 CR1-07 Fab complex Deposited 2017-06-03 | Assembly 2 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain C
112–218(107 aa)
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
BATCH MODE;pH 5.5;297 K;1.8 M AmSO4 and 100 mM NaCitrate pH 5.5.
|
Resolution 3.91 Å R-free 0.264 |
| 5W1M MACV GP1 CR1-07 Fab complex Deposited 2017-06-03 | Assembly 3 Other combination Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain E
112–218(107 aa)
|
Not recorded | BMA beta-D-mannopyranose × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
BATCH MODE;pH 5.5;297 K;1.8 M AmSO4 and 100 mM NaCitrate pH 5.5.
|
Resolution 3.91 Å R-free 0.264 |
| 5W1M MACV GP1 CR1-07 Fab complex Deposited 2017-06-03 | Assembly 4 Other combination Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain G
112–218(107 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
BATCH MODE;pH 5.5;297 K;1.8 M AmSO4 and 100 mM NaCitrate pH 5.5.
|
Resolution 3.91 Å R-free 0.264 |