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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：Q13219 New Search
8PDB entries
8Biological assembly
16chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
7UFG Cryo-EM structure of PAPP-A in complex with IGFBP5 Deposited 2022-03-22 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 81–1627（1547 aa）
Chain B 81–1627（1547 aa）
Mutation：E483A, S1144Y Mutation：E483A, S1144Y ZN ZINC ION × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 9.2；BTP (Bis-Tris-Propane) pH 9.2
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.28 Å
7Y5N Structure of 1:1 PAPP-A.ProMBP complex(half map) Deposited 2022-06-17 Assembly 1 Other combination Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain C 81–1627（1547 aa）
Chain D 81–1627（1547 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 10 ZN ZINC ION × 1 CA CALCIUM ION × 7 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.45 Å
7Y5Q Structure of 1:1 PAPP-A.STC2 complex(half map) Deposited 2022-06-17 Assembly 1 Insufficient information Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 81–1627（1547 aa）
Chain B 81–1627（1547 aa）
Not recorded ZN ZINC ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.80 Å
8A7D Partial dimer complex of PAPP-A and its inhibitor STC2 Deposited 2022-06-20 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain C 82–1617（1536 aa）
Chain Q 82–1617（1536 aa）
Mutation：E563Q Mutation：E563Q NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 8 ZN ZINC ION × 1 CA CALCIUM ION × 8 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4；Hepes buffer, 20 mM Hepes pH 7.4 100 mM NaCl, 1 mM CaCl
cryo-EM vitrification conditions Cryogen ETHANE；4 s
Resolution 3.06 Å
8A7E PAPP-A dimer in complex with its inhibitor STC2 Deposited 2022-06-20 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain C 82–1617（1536 aa）
Chain Q 82–1617（1536 aa）
Mutation：E563Q Mutation：E563Q ZN ZINC ION × 2 CA CALCIUM ION × 16 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4；HEPES buffer 20 mM Hepes pH 7.5 100 mM NaCl, 1mM CaCl
cryo-EM vitrification conditions Cryogen ETHANE；Blot time 4.5 sec
Resolution 5.02 Å
8D8O Cryo-EM structure of substrate unbound PAPP-A Deposited 2022-06-08 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 81–1627（1547 aa）
Chain B 81–1627（1547 aa）
Mutation：E483A, S1144Y Mutation：E483A, S1144Y ZN ZINC ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 9.2；BTP (Bis-Tris-Propane) pH 9.2
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.35 Å
8HGG Structure of 2:2 PAPP-A.ProMBP complex Deposited 2022-11-14 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain C 1–1627（1627 aa）
Chain D 1–1627（1627 aa）
Not recorded ZN ZINC ION × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.64 Å
8HGH Structure of 2:2 PAPP-A.STC2 complex Deposited 2022-11-14 Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 81–1627（1547 aa）
Chain B 81–1627（1547 aa）
Not recorded ZN ZINC ION × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.16 Å

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.