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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：Q13283 New Search
20PDB entries
30Biological assembly
102chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
3Q90 Crystal structure of the NTF2 domain of Ras GTPase-activating protein-binding protein 1 Deposited 2011-01-07 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–139（139 aa） Fragment：unp residues 1-139
Chain B 1–139（139 aa） Fragment：unp residues 1-139
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5.5；277 K；25% w/v PEG3350, 0.2M AMMONIUM ACETATE, 0.1M BIS-TRIS, VAPOR DIFFUSION, SITTING DROP, temperature 277K, pH 5.5
Resolution 1.70 Å R-free 0.238
4FCJ Crystal structure of the NTF2-like domain of human G3BP1 Deposited 2012-05-25 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–139（139 aa） Fragment：NTF2-like domain
Chain B 1–139（139 aa） Fragment：NTF2-like domain
Not recorded GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.5；279 K；20% PEG3350, 0.1 M Bis-tris, pH 5.5, VAPOR DIFFUSION, HANGING DROP, temperature 279K
Resolution 1.62 Å R-free 0.231
4FCM Crystal structure of the NTF2-like domain of human G3BP1 in complex with a peptide Deposited 2012-05-25 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 1–139（139 aa） Fragment：NTF2-like domain
Chain B 1–139（139 aa） Fragment：NTF2-like domain
Not recorded PO4 PHOSPHATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5.5；279 K；20% PEG3350, 0.1 M Bis-tris, pH 5.5, VAPOR DIFFUSION, SITTING DROP, temperature 279K
Resolution 2.69 Å R-free 0.282
4IIA Low resolution crystal structure of the NTF2-like domain of human G3BP1 Deposited 2012-12-20 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 11–139（129 aa） Fragment：NTF2-LIKE DOMAIN
Not recorded PO4 PHOSPHATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；293 K；1.6 M diammonium phosphate, 0.1 M MOPS, pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 3.30 Å R-free 0.359
5FW5 Crystal structure of human G3BP1 in complex with Semliki Forest Virus nsP3-25 comprising two FGDF motives Deposited 2016-02-12 Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain A 1–139（139 aa） Fragment：NTF2-LIKE, RESIDUES 1-139
Chain B 1–139（139 aa） Fragment：NTF2-LIKE, RESIDUES 1-139
Not recorded SO4 SULFATE ION × 8 ACT ACETATE ION × 4 GOL GLYCEROL × 8 K POTASSIUM ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions 0.1 M SODIUM ACETATE TRIHYDRATE PH 4.6, 2 M AMMONIUMSULFATE
Resolution 1.92 Å R-free 0.202
6TA7 CRYSTAL STRUCTURE OF HUMAN G3BP1-NTF2 IN COMPLEX WITH HUMAN CAPRIN1-DERIVED SOLOMON MOTIF Deposited 2019-10-29 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–139（139 aa）
Chain E 1–139（139 aa）
Not recorded NA SODIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；298 K；0.2M Sodium chloride, 0.1M Tris 8.0, 20% w/v PEG 4000 of the Proplex crystallization screen (Molecular Dimensions)
Resolution 1.93 Å R-free 0.252
6TA7 CRYSTAL STRUCTURE OF HUMAN G3BP1-NTF2 IN COMPLEX WITH HUMAN CAPRIN1-DERIVED SOLOMON MOTIF Deposited 2019-10-29 Assembly 2 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain B 1–139（139 aa）
Chain F 1–139（139 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；298 K；0.2M Sodium chloride, 0.1M Tris 8.0, 20% w/v PEG 4000 of the Proplex crystallization screen (Molecular Dimensions)
Resolution 1.93 Å R-free 0.252
6TA7 CRYSTAL STRUCTURE OF HUMAN G3BP1-NTF2 IN COMPLEX WITH HUMAN CAPRIN1-DERIVED SOLOMON MOTIF Deposited 2019-10-29 Assembly 3 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain C 1–139（139 aa）
Chain D 1–139（139 aa）
Not recorded NA SODIUM ION × 1 CL CHLORIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；298 K；0.2M Sodium chloride, 0.1M Tris 8.0, 20% w/v PEG 4000 of the Proplex crystallization screen (Molecular Dimensions)
Resolution 1.93 Å R-free 0.252
7S17 Crystal structure of human G3BP1-NTF2 with three mutations- F15W, F33W, and F124W Deposited 2021-09-01 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–138（138 aa）
Chain B 1–138（138 aa）
Mutation：F15W, F33W, F124W Mutation：F15W, F33W, F124W No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；291 K；20% PEG 8000, 100 mM HEPES
Resolution 2.36 Å R-free 0.271
7SUO Crystal Structure of the G3BP1 NTF2-like domain bound to the IDR1 of SARS-CoV-2 nucleocapsid protein Deposited 2021-11-17 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 2–139（138 aa）
Chain B 2–139（138 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；277.15 K；20% propan-2-ol, 0.1 M MES monohydrate (pH 6.0), 20% PEG MME 20,000
Resolution 2.35 Å R-free 0.248
7XHF Crystal structure of the NTF2L domain of human G3BP1 in complex with the USP10 derived peptide Deposited 2022-04-08 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 1–139（139 aa）
Chain B 1–139（139 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；289.15 K；0.1 M Sodium citrate tribasic dihydrate pH 5.0; 19 % w/v Polyethylene glycol 3,350
Resolution 2.68 Å R-free 0.254
7XHG Crystal structure of the NTF2L domain of human G3BP1 in complex with the Caprin-1 derived peptide Deposited 2022-04-08 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 1–139（139 aa）
Chain D 1–139（139 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；289.15 K；0.2 M Sodium acetate trihydrate, 0.1 M Sodium cacodylate trihydrate pH 6.5, 30 % w/v Polyethylene glycol 8,000
Resolution 2.46 Å R-free 0.275
7XHG Crystal structure of the NTF2L domain of human G3BP1 in complex with the Caprin-1 derived peptide Deposited 2022-04-08 Assembly 2 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 1–139（139 aa）
Chain C 1–139（139 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；289.15 K；0.2 M Sodium acetate trihydrate, 0.1 M Sodium cacodylate trihydrate pH 6.5, 30 % w/v Polyethylene glycol 8,000
Resolution 2.46 Å R-free 0.275
8TH1 Crystal Structure of the G3BP1 NTF2-like domain bound to the IDR1 of SARS-CoV-2 nucleocapsid protein D3L mutant Deposited 2023-07-13 Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count
Chain A 1–139（139 aa）
Chain B 1–139（139 aa）
Chain C 1–139（139 aa）
Chain D 1–139（139 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；277.15 K；0.2 M sodium thiocyanate, 20% PEG 3350
Resolution 1.80 Å R-free 0.238
8TH5 Crystal Structure of the G3BP1 NTF2-like domain bound to the IDR1 of SARS-CoV-2 nucleocapsid protein P13L mutant Deposited 2023-07-13 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 1–139（139 aa）
Chain F 1–139（139 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.5；277.15 K；0.2 M lithium sulfate, 0.1 M Tris pH 8.5, 25% PEG3350
Resolution 2.62 Å R-free 0.336
8TH5 Crystal Structure of the G3BP1 NTF2-like domain bound to the IDR1 of SARS-CoV-2 nucleocapsid protein P13L mutant Deposited 2023-07-13 Assembly 2 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 1–139（139 aa）
Chain E 1–139（139 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.5；277.15 K；0.2 M lithium sulfate, 0.1 M Tris pH 8.5, 25% PEG3350
Resolution 2.62 Å R-free 0.336
8TH5 Crystal Structure of the G3BP1 NTF2-like domain bound to the IDR1 of SARS-CoV-2 nucleocapsid protein P13L mutant Deposited 2023-07-13 Assembly 3 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain C 1–139（139 aa）
Chain H 1–139（139 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.5；277.15 K；0.2 M lithium sulfate, 0.1 M Tris pH 8.5, 25% PEG3350
Resolution 2.62 Å R-free 0.336
8TH5 Crystal Structure of the G3BP1 NTF2-like domain bound to the IDR1 of SARS-CoV-2 nucleocapsid protein P13L mutant Deposited 2023-07-13 Assembly 4 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain D 1–139（139 aa）
Chain G 1–139（139 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.5；277.15 K；0.2 M lithium sulfate, 0.1 M Tris pH 8.5, 25% PEG3350
Resolution 2.62 Å R-free 0.336
8TH5 Crystal Structure of the G3BP1 NTF2-like domain bound to the IDR1 of SARS-CoV-2 nucleocapsid protein P13L mutant Deposited 2023-07-13 Assembly 5 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain I 1–139（139 aa）
Chain J 1–139（139 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.5；277.15 K；0.2 M lithium sulfate, 0.1 M Tris pH 8.5, 25% PEG3350
Resolution 2.62 Å R-free 0.336
8TH6 Crystal Structure of the G3BP1 NTF2-like domain bound to USP10 peptide Deposited 2023-07-14 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 1–139（139 aa）
Chain D 1–139（139 aa）
Not recorded EDO 1,2-ETHANEDIOL × 11 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；277.15 K；0.1 M HEPES pH 7.5, 25% PEG3350
Resolution 2.34 Å R-free 0.295
8TH6 Crystal Structure of the G3BP1 NTF2-like domain bound to USP10 peptide Deposited 2023-07-14 Assembly 2 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 1–139（139 aa）
Chain C 1–139（139 aa）
Not recorded EDO 1,2-ETHANEDIOL × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；277.15 K；0.1 M HEPES pH 7.5, 25% PEG3350
Resolution 2.34 Å R-free 0.295
8TH7 Crystal Structure of the G3BP1 NTF2-like domain bound to the Caprin1 peptide Deposited 2023-07-14 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 1–139（139 aa）
Chain B 1–139（139 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；291.15 K；1.8M tri-ammonium citrate pH 7.0
Resolution 2.88 Å R-free 0.277
8V1L Crystal structure of the NTF2L domain of human G3BP1 in complex with small molecule Deposited 2023-11-20 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–139（139 aa）
Chain C 1–139（139 aa）
Not recorded Y9M N-[(2S)-2-fluoro-4,4-dimethylpentanoyl]-3-hydroxy-L-valyl-(betaS)-beta-methyl-L-phenylalanyl-D-alanyl-N-benzyl-N,O-dimethyl-L-homoserinamide × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；0.1 M MES pH 6.5, 15% PEG 550 MME
Resolution 2.68 Å R-free 0.395
8V1L Crystal structure of the NTF2L domain of human G3BP1 in complex with small molecule Deposited 2023-11-20 Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 1–139（139 aa）
Chain D 1–139（139 aa）
Not recorded Y9M N-[(2S)-2-fluoro-4,4-dimethylpentanoyl]-3-hydroxy-L-valyl-(betaS)-beta-methyl-L-phenylalanyl-D-alanyl-N-benzyl-N,O-dimethyl-L-homoserinamide × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；0.1 M MES pH 6.5, 15% PEG 550 MME
Resolution 2.68 Å R-free 0.395
8V1L Crystal structure of the NTF2L domain of human G3BP1 in complex with small molecule Deposited 2023-11-20 Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain E 1–139（139 aa）
Chain F 1–139（139 aa）
Not recorded Y9M N-[(2S)-2-fluoro-4,4-dimethylpentanoyl]-3-hydroxy-L-valyl-(betaS)-beta-methyl-L-phenylalanyl-D-alanyl-N-benzyl-N,O-dimethyl-L-homoserinamide × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；0.1 M MES pH 6.5, 15% PEG 550 MME
Resolution 2.68 Å R-free 0.395
9CC6 De novo design of high-affinity protein binders to RNA binding domain of G3bp1 Deposited 2024-06-20 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 453–465（13 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；0.05 M Calcium chloride dihydrate, 0.1 M BIS-TRIS pH 6.5, and 30% v/v Polyethylene glycol monomethyl ether 550
Resolution 2.40 Å R-free 0.258
9IVQ Cryo-EM structure of the CHIKV nsP3 peptide in complex with the NTF2L domain of G3BP1 (Conformation I) Deposited 2024-07-24 Assembly 1 Protein heterocomplex Heteromer；Protein × 24 PDB declaration: 24-meric（24） Consistent with protein count
Chain A 1–138（138 aa）
Chain B 1–138（138 aa）
Chain C 1–138（138 aa）
Chain D 1–138（138 aa）
Chain E 1–138（138 aa）
Chain F 1–138（138 aa）
Chain G 1–138（138 aa）
Chain H 1–138（138 aa）
Chain M 1–138（138 aa）
Chain N 1–138（138 aa）
Chain O 1–138（138 aa）
Chain P 1–138（138 aa）
Chain Q 1–138（138 aa）
Chain R 1–138（138 aa）
Chain S 1–138（138 aa）
Chain T 1–138（138 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.66 Å
9IVR Cryo-EM structure of the CHIKV nsP3 peptide in complex with the NTF2L domain of G3BP1 (Conformation II) Deposited 2024-07-24 Assembly 1 Protein heterocomplex Heteromer；Protein × 24 PDB declaration: 24-meric（24） Consistent with protein count
Chain A 1–138（138 aa）
Chain B 1–138（138 aa）
Chain C 1–138（138 aa）
Chain D 1–138（138 aa）
Chain E 1–138（138 aa）
Chain F 1–138（138 aa）
Chain G 1–138（138 aa）
Chain H 1–138（138 aa）
Chain M 1–138（138 aa）
Chain N 1–138（138 aa）
Chain O 1–138（138 aa）
Chain P 1–138（138 aa）
Chain Q 1–138（138 aa）
Chain R 1–138（138 aa）
Chain S 1–138（138 aa）
Chain T 1–138（138 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.80 Å
9IVS Cryo-EM structure of the CHIKV nsP3 peptide in complex with the NTF2L domain of G3BP1 (Conformation III) Deposited 2024-07-24 Assembly 1 Protein heterocomplex Heteromer；Protein × 24 PDB declaration: 24-meric（24） Consistent with protein count
Chain A 1–138（138 aa）
Chain B 1–138（138 aa）
Chain C 1–138（138 aa）
Chain D 1–138（138 aa）
Chain E 1–138（138 aa）
Chain F 1–138（138 aa）
Chain G 1–138（138 aa）
Chain H 1–138（138 aa）
Chain M 1–138（138 aa）
Chain N 1–138（138 aa）
Chain O 1–138（138 aa）
Chain P 1–138（138 aa）
Chain Q 1–138（138 aa）
Chain R 1–138（138 aa）
Chain S 1–138（138 aa）
Chain T 1–138（138 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.97 Å
9J5S Crystal structure of human G3BP1 in complex with CHIKV nsP3 peptide Deposited 2024-08-13 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 1–138（138 aa）
Chain B 1–138（138 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 4；291 K；20%(w/v) PEG 3350, 200mM Sodium citrate tribasic, 100mM Sodium citrate/Citric acid pH 4.0
Resolution 2.84 Å R-free 0.280

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.