Current Protein Identity：Q14315
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1V05 Dimerization of human Filamin C: crystal structure of the domain 24 Deposited 2004-03-22 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
2633–2725（93 aa）
Fragment：ROD DOMAIN, RESIDUES 2633-2725
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7.5；1.6M NA CITRATE, 0.1M HEPES, PH7.5, pH 7.50
|
Resolution 1.43 Å R-free 0.205 |
| 2D7M Solution structure of the 14th Filamin domain from human Filamin C Deposited 2005-11-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1536–1637（102 aa）
Fragment：Filamin domain
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7；296 K；Ionic strength (raw mmCIF value) 120mM；Pressure ambient
NMR sample composition
1.22mM Filamin domain U-15N,13C; 20mM d-Tris-HCl(pH 7.0); 100mM NaCl; 1mM d-DTT; 0.02% NaN3; 10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2D7N Solution structure of the 16th Filamin domain from human Filamin C Deposited 2005-11-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1782–1861（80 aa）
Fragment：Filamin domain
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7；296 K；Ionic strength (raw mmCIF value) 120mM；Pressure ambient
NMR sample composition
1.19mM Filamin domain U-15N,13C; 20mM d-Tris-HCl(pH 7.0); 100mM NaCl; 1mM d-DTT; 0.02% NaN3; 10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2D7O Solution structure of the 17th Filamin domain from human Filamin C Deposited 2005-11-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1856–1953（98 aa）
Fragment：Filamin domain
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7；298 K；Ionic strength (raw mmCIF value) 120mM；Pressure ambient
NMR sample composition
1.16mM Filamin domain U-15N,13C; 20mM d-Tris-HCl(pH 7.0); 100mM NaCl; 1mM d-DTT; 0.02% NaN3; 10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2D7P Solution structure of the 22th Filamin domain from human Filamin C Deposited 2005-11-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2402–2500（99 aa）
Fragment：Filamin domain
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7；296 K；Ionic strength (raw mmCIF value) 120mM；Pressure ambient
NMR sample composition
1.24mM Filamin domain U-15N,13C; 20mM d-Tris-HCl(pH 7.0); 100mM NaCl; 1mM d-DTT; 0.02% NaN3; 10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2D7Q Solution structure of the 23th Filamin domain from human Filamin C Deposited 2005-11-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2500–2599（100 aa）
Fragment：Filamin domain
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7；296 K；Ionic strength (raw mmCIF value) 120mM；Pressure ambient
NMR sample composition
1.13mM Filamin domain U-15N,13C; 20mM d-Tris-HCl(pH 7.0); 100mM NaCl; 1mM d-DTT; 0.02% NaN3; 10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2NQC Crystal structure of ig-like domain 23 from human filamin C Deposited 2006-10-31 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2495–2598（104 aa）
Fragment：Ig-like domain 23
|
Not recorded | NI NICKEL (II) ION × 1 IMD IMIDAZOLE × 2 GOL GLYCEROL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；293 K；17.5% PEG 10000, 0.2M imidazole malate, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.05 Å R-free 0.237 |
| 3V8O Human Filamin C Ig - like Domains 4 and 5 Deposited 2011-12-23 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
569–761（193 aa）
Fragment：Domains 4 and 5 (UNP residues 569-761)
|
Not recorded | K POTASSIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；293 K；1.6M Sodium Potassium Phosphate, pH 8, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.80 Å R-free 0.255 |
| 3V8O Human Filamin C Ig - like Domains 4 and 5 Deposited 2011-12-23 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
569–761（193 aa）
Fragment：Domains 4 and 5 (UNP residues 569-761)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；293 K；1.6M Sodium Potassium Phosphate, pH 8, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.80 Å R-free 0.255 |
| 4MGX Crystal structure of human filamin C domains 4-5 and GPIB alpha cytoplasmic domain complex Deposited 2013-08-29 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
572–756（185 aa）
Fragment：domains 4 and 5 (UNP residues 572-756)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；297 K；0.1 M HEPES, pH 7.5, 20% w/v PEG8000, VAPOR DIFFUSION, HANGING DROP, temperature 297K
|
Resolution 3.16 Å R-free 0.277 |
| 7OUU Crystal structure of human filamin C domains 14-15 Deposited 2021-06-13 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1534–1736（203 aa）
Chain B
1534–1736（203 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；295.15 K；0.1 M HEPES 7.0, 30 % v/v Jeffamine ED-2003
|
Resolution 1.47 Å R-free 0.228 |
| 7OUV Crystal structure of human filamin C domains 14-15 cardiovascular disease causing mutation S1624L Deposited 2021-06-13 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1534–1736（203 aa）
Chain B
1534–1736（203 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 5；295.15 K；0.1 M SPG pH 5.0, 25% w/v PEG 1500
|
Resolution 1.80 Å R-free 0.240 |
| 7P0E Crystal structure of human filamin C domains 14-15 cardiovascular disease causing mutation G1676R Deposited 2021-06-29 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1534–1736（203 aa）
Chain B
1534–1736（203 aa）
|
Not recorded | GOL GLYCEROL × 4 EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION；pH 6；295.15 K；0.1 M BIS-TRIS pH 6.0, 26.3 % w/v PEG 3350, 5% w/v Glycerol
|
Resolution 1.60 Å R-free 0.221 |
| 8PA0 cvHsp (HspB7) C131S alpha-crystallin domain - filamin C (FLNC) domain 24 complex Deposited 2023-06-06 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2630–2725（96 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；0.1 mM HEPES and 20% w/v PEG 8000, pH 7.0
|
Resolution 2.85 Å R-free 0.291 |