Current Protein Identity：Q15075
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1HYI SOLUTION STRUCTURE OF THE EEA1 FYVE DOMAIN COMPLEXED WITH INOSITOL 1,3-BISPHOSPHATE Deposited 2001-01-19 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1346–1410（65 aa）
Fragment：FYVE DOMAIN (RESIDUES 1346-1410)
|
Not recorded | ZN ZINC ION × 2 ITP PHOSPHORIC ACID MONO-(2,3,4,6-TETRAHYDROXY-5-PHOSPHONOOXY-CYCLOHEXYL) ESTER × 1 | SOLUTION NMR |
NMR measurement conditions
pH 6.7；298 K；Ionic strength (raw mmCIF value) 200 mM KCl；Pressure 1
NMR sample composition
1mM FYVE domain; 20 mM d-Tris buffer; pH 6.7; 200 mM KCl; 20 mM d-DTT; 1 mM NaN3 | 90% H2O/10% D2O
NMR sample composition
1mM FYVE domain; 20 mM d-Tris buffer; pH 6.7; 200 mM KCl; 20 mM d-DTT; 1 mM NaN3 | 99.99% D2O
|
Resolution not provided |
| 1HYJ SOLUTION STRUCTURE OF THE EEA1 FYVE DOMAIN Deposited 2001-01-19 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1346–1410（65 aa）
Fragment：FYVE DOMAIN (RESIDUES 1346-1410)
|
Not recorded | ZN ZINC ION × 2 | SOLUTION NMR |
NMR measurement conditions
pH 6.7；298 K；Ionic strength (raw mmCIF value) 200 mM KCl；Pressure 1
NMR sample composition
1mM FYVE domain; 20 mM d-Tris buffer; pH 6.7; 200 mM KCl; 20 mM d-DTT; 1 mM NaN3 | 90% H2O/10% D2O
NMR sample composition
1mM FYVE domain; 20 mM d-Tris buffer; pH 6.7; 200 mM KCl; 20 mM d-DTT; 1 mM NaN3 | 99.99% D2O
|
Resolution not provided |
| 1JOC EEA1 homodimer of C-terminal FYVE domain bound to inositol 1,3-diphosphate Deposited 2001-07-27 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1287–1410（124 aa）
Fragment：C-terminal domain, FYVE domain
Chain B
1287–1410（124 aa）
Fragment：C-terminal domain, FYVE domain
|
Not recorded | ZN ZINC ION × 4 ITP PHOSPHORIC ACID MONO-(2,3,4,6-TETRAHYDROXY-5-PHOSPHONOOXY-CYCLOHEXYL) ESTER × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；11% PEG 4000, 50 mM HEPES, 60 mM ammonium acetate, 10% glycerol, and 1.5 mM Ins(1,3)P2, pH 7.0, VAPOR DIFFUSION, HANGING DROP
|
Resolution 2.20 Å R-free 0.281 |
| 3MJH Crystal Structure of Human Rab5A in complex with the C2H2 Zinc Finger of EEA1 Deposited 2010-04-12 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
36–69（34 aa）
Fragment：C2H2-type, residues 36-69
|
Not recorded | GTP GUANOSINE-5'-TRIPHOSPHATE × 1 MG MAGNESIUM ION × 1 ZN ZINC ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5；291 K；18% PEG 4000, 50mM sodium acetate, 0.2M sodium-potassium phosphate, 10% glycerol, pH 5.0, VAPOR DIFFUSION, HANGING DROP, temperature 291.0K
|
Resolution 2.03 Å R-free 0.260 |
| 3MJH Crystal Structure of Human Rab5A in complex with the C2H2 Zinc Finger of EEA1 Deposited 2010-04-12 | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain D
36–69（34 aa）
Fragment：C2H2-type, residues 36-69
|
Not recorded | GTP GUANOSINE-5'-TRIPHOSPHATE × 1 MG MAGNESIUM ION × 1 ZN ZINC ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5；291 K；18% PEG 4000, 50mM sodium acetate, 0.2M sodium-potassium phosphate, 10% glycerol, pH 5.0, VAPOR DIFFUSION, HANGING DROP, temperature 291.0K
|
Resolution 2.03 Å R-free 0.260 |