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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：Q6MZV7 New Search
21PDB entries
26Biological assembly
48chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
5NSC Fc DEKK heterodimer variant Deposited 2017-04-26 Assembly 1 Other combination Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 242–473（232 aa）
Chain B 242–473（232 aa）
Mutation：L351K, T366K Mutation：L351D, L368E GOL GLYCEROL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；291 K；0.2 M sodium fluoride, 20% w/v PEG3350
Resolution 2.30 Å R-free 0.265
5NSG Fc DEDE homodimer variant Deposited 2017-04-26 Assembly 1 Other combination Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 242–473（232 aa）
Mutation：L351D, L368E ZN ZINC ION × 6 ACT ACETATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.5；291 K；acetate buffer pH 4.5, 0.2 M zinc acetate, 16% w/v PEG 3000
Resolution 2.22 Å R-free 0.243
5U4Y IgG Fc bound to 3 helix of the B-domain from Protein A Deposited 2016-12-06 Assembly 1 Other combination Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 261–472（212 aa） Fragment：unp residues 261-472
Chain B 261–472（212 aa） Fragment：unp residues 261-472
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；293 K；25% PEG 3400, 0.1M magnesium acetate, 0.1 M HEPES pH 7.0. Protein concentration 5mg/mL.
Resolution 2.50 Å R-free 0.230
5U52 2 helix minimized version of the B-domain from Protein A (Z34C0 bound to IgG1 Fc (monoclinic form) Deposited 2016-12-06 Assembly 1 Other combination Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 262–469（208 aa） Fragment：unp residues 262-469
Chain B 262–469（208 aa） Fragment：unp residues 262-469
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；20% PEG monomethyl ether 550, 0.1M bis-tris propane pH 6.5, 0.1M NaCl, 5mg/mL protein concentration.
Resolution 1.94 Å R-free 0.228
5U66 Modified single helix from the B-domain of protein A bound to IgG1 Fc Deposited 2016-12-07 Assembly 1 Other combination Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 263–469（207 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.2；293 K；20% PEG 4000, 0.1M HEPES pH 7.2, 5mg/mL protein concentration.
Resolution 1.70 Å R-free 0.227
5VME Crystal structure of human IgG1 Fc K248E, T437R mutant Deposited 2017-04-27 Assembly 1 Other combination Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 251–473（223 aa）
Chain B 251–473（223 aa）
Mutation：K248, T437R Mutation：K248, T437R No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；35.5% PEG 300, 0.1 M HEPES, pH 7.0
Resolution 3.10 Å R-free 0.285
6CHF Crystal structure of a Fc fragment LALA mutant (L234A, L235A) of human IgG1 (crystal form 1) Deposited 2018-02-22 Assembly 1 Other combination Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 260–473（214 aa）
Chain B 260–473（214 aa）
Mutation：L234A L235A Mutation：L234A L235A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；294 K；20% PEG MME 5,000 0.1 M Bis-Tris pH 6.5
Resolution 2.40 Å R-free 0.273
6CJC CRYSTAL STRUCTURE OF A FC FRAGMENT LALA MUTANT (L234A, L235A) OF HUMAN IGG1 (CRYSTAL FORM 3) Deposited 2018-02-26 Assembly 1 Other combination Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 260–473（214 aa）
Chain B 260–473（214 aa）
Mutation：L234A, L235A Mutation：L234A, L235A CL CHLORIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；294 K；20% PEG MME 5,000 0.1 M Bis-Tris. pH 6.5
Resolution 2.58 Å R-free 0.241
6CJX Crystal structure of a Fc fragment LALA mutant (L234A, L235A) of human IgG1 (crystal form 2) Deposited 2018-02-27 Assembly 1 Other combination Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 260–473（214 aa）
Chain B 260–473（214 aa）
Mutation：L234A, L235A Mutation：L234A, L235A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；294 K；25% PEG 3,350 0.1 M Bus-Tris pH 6.5
Resolution 2.44 Å R-free 0.264
6N9T Structure of a peptide-based photo-affinity cross-linker with Herceptin Fc Deposited 2018-12-04 Assembly 1 Other combination Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 249–472（224 aa） Fragment：residues 249-472
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；291 K；100mM sodium acetate pH=5.6, 12%(w/v) PEG 1000
Resolution 2.58 Å R-free 0.265
6N9T Structure of a peptide-based photo-affinity cross-linker with Herceptin Fc Deposited 2018-12-04 Assembly 2 Other combination Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 249–472（224 aa） Fragment：residues 249-472
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；291 K；100mM sodium acetate pH=5.6, 12%(w/v) PEG 1000
Resolution 2.58 Å R-free 0.265
6P6D HUMAN IGG1 FC FRAGMENT, C239 INSERTION MUTANT Deposited 2019-06-03 Assembly 1 Other combination Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 247–473（227 aa）
Chain B 247–473（227 aa）
Mutation：C239 insertion Mutation：C239 insertion CYS CYSTEINE × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；295 K；12 mg/mL protein, 20% w/v PEG 3350, 200 mM K Acetate
Resolution 2.31 Å R-free 0.268
7LF5 Structure of Hyperglycosylated Human IgG1 Fc (Fc267) Deposited 2021-01-15 Assembly 1 Other combination Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 242–473（232 aa）
Not recorded FUC alpha-L-fucopyranose × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；298 K；CRYSTALS GROWN BY MIXING 1 UL OF FC267 (10 MG/ML IN 10mM HEPES, 75mM NaCl pH 7.4) WITH 1 UL OF PRECIPITANT SOLUTION CONSISTING OF 0.1M HEPES pH 6.5, 8% w/v PEG6000
Resolution 2.60 Å R-free 0.243
7LF9 Structure of Hyperglycosylated Human IgG1 Fc (Fc329) Deposited 2021-01-15 Assembly 1 Other combination Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 242–473（232 aa）
Chain B 242–473（232 aa）
Not recorded FUC alpha-L-fucopyranose × 2 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；298 K；CRYSTALS GROWN BY MIXING 1 UL OF FC329 (10 MG/ML IN 10mM HEPES, 75mM NaCl pH 7.4) WITH 1 UL OF PRECIPITANT SOLUTION CONSISTING OF 0.1M HEPES pH 6.5, 12.571% w/v PEG6000
Resolution 2.20 Å R-free 0.246
7LFN Structure of Hyperglycosylated Human IgG1 Fc (Fc267_329) Deposited 2021-01-17 Assembly 1 Other combination Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 242–473（232 aa）
Chain B 242–473（232 aa）
Not recorded FUC alpha-L-fucopyranose × 2 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；298 K；CRYSTALS GROWN BY MIXING 1 UL OF FC267_329 (10 MG/ML IN 10mM HEPES, 75mM NaCl pH 7.4) WITH 1 UL OF PRECIPITANT SOLUTION CONSISTING OF 0.025M MES pH 7.0, 0.1M KCl, 20.571% w/v PEG3350
Resolution 2.60 Å R-free 0.270
7RHO Human IgG1 Fc fragment, hinge-free, expressed in E. coli Deposited 2021-07-18 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 263–473（211 aa） Fragment：engineered variant
Chain B 263–473（211 aa） Fragment：engineered variant
Not recorded EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 7；295 K；20% (w/v) PEG 6000, 40 mM CaCl2, 100 mM NaHepes
Resolution 2.00 Å R-free 0.270
7RHO Human IgG1 Fc fragment, hinge-free, expressed in E. coli Deposited 2021-07-18 Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain D 263–473（211 aa） Fragment：engineered variant
Chain E 263–473（211 aa） Fragment：engineered variant
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 7；295 K；20% (w/v) PEG 6000, 40 mM CaCl2, 100 mM NaHepes
Resolution 2.00 Å R-free 0.270
7RHO Human IgG1 Fc fragment, hinge-free, expressed in E. coli Deposited 2021-07-18 Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain F 263–473（211 aa） Fragment：engineered variant
Chain G 263–473（211 aa） Fragment：engineered variant
Not recorded EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 7；295 K；20% (w/v) PEG 6000, 40 mM CaCl2, 100 mM NaHepes
Resolution 2.00 Å R-free 0.270
7RHO Human IgG1 Fc fragment, hinge-free, expressed in E. coli Deposited 2021-07-18 Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain J 263–473（211 aa） Fragment：engineered variant
Chain K 263–473（211 aa） Fragment：engineered variant
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 7；295 K；20% (w/v) PEG 6000, 40 mM CaCl2, 100 mM NaHepes
Resolution 2.00 Å R-free 0.270
8F8W Crystal structure of Nb.X0 bound to the afucosylated human IgG1 fragment crystal form I Deposited 2022-11-22 Assembly 1 Other combination Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 247–470（224 aa）
Chain B 247–470（224 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；0.1 M Sodium HEPES 7.5 20 % w/v PEG 8000. Cryopreserved with 12.5% glycerol.
Resolution 2.71 Å R-free 0.241
8F8W Crystal structure of Nb.X0 bound to the afucosylated human IgG1 fragment crystal form I Deposited 2022-11-22 Assembly 2 Other combination Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain E 247–470（224 aa）
Chain F 247–470（224 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；0.1 M Sodium HEPES 7.5 20 % w/v PEG 8000. Cryopreserved with 12.5% glycerol.
Resolution 2.71 Å R-free 0.241
8F8X Crystal structure of Nb.X0 bound to the afucosylated human IgG1 fragment crystal form II Deposited 2022-11-22 Assembly 1 Other combination Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 247–470（224 aa）
Chain B 247–470（224 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；20 % w/v PEG 6000, 0.1 M Sodium citrate 4.0, 0.2 M Lithium chloride. No additional cryoprotectant.
Resolution 2.60 Å R-free 0.285
8Q5U Endoglycosidase S2 in complex with IgG1 Fc Deposited 2023-08-09 Assembly 1 Other combination Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain A 247–473（227 aa）
Chain B 247–473（227 aa）
Chain C 247–473（227 aa）
Mutation：L234C E382A Mutation：L234C E382A Mutation：L234C E382A GOL GLYCEROL × 4 PGE TRIETHYLENE GLYCOL × 5 CA CALCIUM ION × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；298 K；Morpheus (Molecular Dimensions) conditon G12: 0.1 M carboxylic acids(0.2M Sodium formate; 0.2M Ammonium acetate; 0.2M Sodium citrate tribasic dihydrate; 0.2M Potassium sodium tartrate tetrahydrate; 0.2M Sodium oxamate); 0.1 M buffer system 3(Tris (base); BICINE); pH 8.5; 37.5 v/v Precipitant Mix 4 (25% v/v MPD; 25% PEG 1000; 25% w/v PEG 3350)
Resolution 3.00 Å R-free 0.252
9IUJ Integrin alpha-v beta-3 in complex with rhodostomin Deposited 2024-07-22 Assembly 1 Insufficient information Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 247–473（227 aa）
Chain B 247–473（227 aa）
Not recorded CA CALCIUM ION × 7 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.78 Å
9JEI Integrin alpha-v beta-3 in complex with Echistatin Deposited 2024-09-03 Assembly 1 Insufficient information Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 247–473（227 aa）
Chain B 247–473（227 aa）
Not recorded CA CALCIUM ION × 7 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.16 Å
9LT3 Integrin alpha-v beta-3 in complex with Trimucrin Deposited 2025-02-05 Assembly 1 Insufficient information Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 247–473（227 aa）
Chain B 247–473（227 aa）
Not recorded CA CALCIUM ION × 7 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.79 Å

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.