Current Protein Identity:Q6PFX9
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 3UTM Crystal structure of a mouse Tankyrase-Axin complex Deposited 2011-11-26 | Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain A
308–655(348 aa)
Fragment:mTNKS1 ARC23 (UNP Residues 308-655)
Chain B
308–655(348 aa)
Fragment:mTNKS1 ARC23 (UNP Residues 308-655)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION;pH 5.6;295 K;0.06 M sodium citrate tribasic dihydrate pH 5.6, 1.2M ammonium acetate, 18% MPD, and 20mM DTT, EVAPORATION, temperature 295K
|
Resolution 2.00 Å R-free 0.238 |
| 4N4T Co-crystal structure of tankyrase 1 with compound 3 [(4S)-3-{4-[6-amino-5-(pyrimidin-2-yl)pyridin-3-yl]phenyl}-5,5-dimethyl-4-phenyl-1,3-oxazolidin-2-one] Deposited 2013-10-08 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
1097–1307(211 aa)
Fragment:UNP residues 1104-1314
|
Not recorded | ZN ZINC ION × 1 2GV (4S)-3-{4-[6-amino-5-(pyrimidin-2-yl)pyridin-3-yl]phenyl}-5,5-dimethyl-4-phenyl-1,3-oxazolidin-2-one × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;277 K;0.2-0.4 M DiAmmonium Tartrate, 12.5-25% PEG 3350, pH 5.0-6.0, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
Resolution 2.31 Å R-free 0.275 |
| 4N4T Co-crystal structure of tankyrase 1 with compound 3 [(4S)-3-{4-[6-amino-5-(pyrimidin-2-yl)pyridin-3-yl]phenyl}-5,5-dimethyl-4-phenyl-1,3-oxazolidin-2-one] Deposited 2013-10-08 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
1097–1307(211 aa)
Fragment:UNP residues 1104-1314
|
Not recorded | ZN ZINC ION × 1 2GV (4S)-3-{4-[6-amino-5-(pyrimidin-2-yl)pyridin-3-yl]phenyl}-5,5-dimethyl-4-phenyl-1,3-oxazolidin-2-one × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;277 K;0.2-0.4 M DiAmmonium Tartrate, 12.5-25% PEG 3350, pH 5.0-6.0, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
Resolution 2.31 Å R-free 0.275 |
| 5HKP Crystal structure of mouse Tankyrase/human TRF1 complex Deposited 2016-01-14 | Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain A
308–655(348 aa)
Fragment:UNP residues 308-655
Chain B
308–655(348 aa)
Fragment:UNP residues 308-655
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;293 K;0.035M Calcium Chloride dihydrate
0.07M MES monohydrate pH6.0
0.03M Tris pH8.5
31.5% v/v Polyethylene glycol 200
6% v/v Ethanol
|
Resolution 2.20 Å R-free 0.229 |
| 6CF6 RNF146 TBM-Tankyrase ARC2-3 complex Deposited 2018-02-13 | Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain A
308–655(348 aa)
Chain B
308–655(348 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;277 K;30 mM sodium citrate pH 5.6, 60 mM ammonium acetate, 27% 2-methyl-2,4-pentanediol
|
Resolution 1.93 Å R-free 0.228 |