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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：Q76SB0 New Search
7PDB entries
19Biological assembly
37chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
2YPY KSHV LANA (ORF73) C-terminal domain, decameric ring: monoclinic crystal form Deposited 2012-11-02 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain G 1013–1149（137 aa） Fragment：C-TERMINAL DOMAIN, RESIDUES 1013-1149
Chain H 1013–1149（137 aa） Fragment：C-TERMINAL DOMAIN, RESIDUES 1013-1149
Not recorded CL CHLORIDE ION × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 9；285 K；1.5 UL OF 2.0 MM PROTEIN IN 5 MM BISTRIS, PH 6.5, 10 MM DTT WERE ADDED TO 1.5 UL OF 0.1 M SODIUM BICINE, PH 9.0, 1.0 M LITHIUM CHLORIDE, 7 % (W/V) PEG 6000. THE MIXTURE WAS INCUBATED AT 12 DEGREES CENTIGRADE IN A HANGING DROP SETUP. CRYSTALS GREW IN A FEW DAYS AND WERE CRYO-PROTECTED BY SHORT SOAKING IN 0.1 M SODIUM BICINE, PH 9.0, 1.0 M LITHIUM CHLORIDE, 7 % (W/V) PEG 6000, 25 % (V/V) GLYCEROL.
Resolution 2.45 Å R-free 0.252
2YPY KSHV LANA (ORF73) C-terminal domain, decameric ring: monoclinic crystal form Deposited 2012-11-02 Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain C 1013–1149（137 aa） Fragment：C-TERMINAL DOMAIN, RESIDUES 1013-1149
Chain D 1013–1149（137 aa） Fragment：C-TERMINAL DOMAIN, RESIDUES 1013-1149
Not recorded CL CHLORIDE ION × 6 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 9；285 K；1.5 UL OF 2.0 MM PROTEIN IN 5 MM BISTRIS, PH 6.5, 10 MM DTT WERE ADDED TO 1.5 UL OF 0.1 M SODIUM BICINE, PH 9.0, 1.0 M LITHIUM CHLORIDE, 7 % (W/V) PEG 6000. THE MIXTURE WAS INCUBATED AT 12 DEGREES CENTIGRADE IN A HANGING DROP SETUP. CRYSTALS GREW IN A FEW DAYS AND WERE CRYO-PROTECTED BY SHORT SOAKING IN 0.1 M SODIUM BICINE, PH 9.0, 1.0 M LITHIUM CHLORIDE, 7 % (W/V) PEG 6000, 25 % (V/V) GLYCEROL.
Resolution 2.45 Å R-free 0.252
2YPY KSHV LANA (ORF73) C-terminal domain, decameric ring: monoclinic crystal form Deposited 2012-11-02 Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1013–1149（137 aa） Fragment：C-TERMINAL DOMAIN, RESIDUES 1013-1149
Chain B 1013–1149（137 aa） Fragment：C-TERMINAL DOMAIN, RESIDUES 1013-1149
Not recorded CL CHLORIDE ION × 6 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 9；285 K；1.5 UL OF 2.0 MM PROTEIN IN 5 MM BISTRIS, PH 6.5, 10 MM DTT WERE ADDED TO 1.5 UL OF 0.1 M SODIUM BICINE, PH 9.0, 1.0 M LITHIUM CHLORIDE, 7 % (W/V) PEG 6000. THE MIXTURE WAS INCUBATED AT 12 DEGREES CENTIGRADE IN A HANGING DROP SETUP. CRYSTALS GREW IN A FEW DAYS AND WERE CRYO-PROTECTED BY SHORT SOAKING IN 0.1 M SODIUM BICINE, PH 9.0, 1.0 M LITHIUM CHLORIDE, 7 % (W/V) PEG 6000, 25 % (V/V) GLYCEROL.
Resolution 2.45 Å R-free 0.252
2YPY KSHV LANA (ORF73) C-terminal domain, decameric ring: monoclinic crystal form Deposited 2012-11-02 Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain E 1013–1149（137 aa） Fragment：C-TERMINAL DOMAIN, RESIDUES 1013-1149
Chain F 1013–1149（137 aa） Fragment：C-TERMINAL DOMAIN, RESIDUES 1013-1149
Not recorded CL CHLORIDE ION × 5 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 9；285 K；1.5 UL OF 2.0 MM PROTEIN IN 5 MM BISTRIS, PH 6.5, 10 MM DTT WERE ADDED TO 1.5 UL OF 0.1 M SODIUM BICINE, PH 9.0, 1.0 M LITHIUM CHLORIDE, 7 % (W/V) PEG 6000. THE MIXTURE WAS INCUBATED AT 12 DEGREES CENTIGRADE IN A HANGING DROP SETUP. CRYSTALS GREW IN A FEW DAYS AND WERE CRYO-PROTECTED BY SHORT SOAKING IN 0.1 M SODIUM BICINE, PH 9.0, 1.0 M LITHIUM CHLORIDE, 7 % (W/V) PEG 6000, 25 % (V/V) GLYCEROL.
Resolution 2.45 Å R-free 0.252
2YPY KSHV LANA (ORF73) C-terminal domain, decameric ring: monoclinic crystal form Deposited 2012-11-02 Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain I 1013–1149（137 aa） Fragment：C-TERMINAL DOMAIN, RESIDUES 1013-1149
Chain J 1013–1149（137 aa） Fragment：C-TERMINAL DOMAIN, RESIDUES 1013-1149
Not recorded CL CHLORIDE ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 9；285 K；1.5 UL OF 2.0 MM PROTEIN IN 5 MM BISTRIS, PH 6.5, 10 MM DTT WERE ADDED TO 1.5 UL OF 0.1 M SODIUM BICINE, PH 9.0, 1.0 M LITHIUM CHLORIDE, 7 % (W/V) PEG 6000. THE MIXTURE WAS INCUBATED AT 12 DEGREES CENTIGRADE IN A HANGING DROP SETUP. CRYSTALS GREW IN A FEW DAYS AND WERE CRYO-PROTECTED BY SHORT SOAKING IN 0.1 M SODIUM BICINE, PH 9.0, 1.0 M LITHIUM CHLORIDE, 7 % (W/V) PEG 6000, 25 % (V/V) GLYCEROL.
Resolution 2.45 Å R-free 0.252
2YPZ KSHV LANA (ORF73) C-terminal domain, decameric ring: orthorhombic crystal form Deposited 2012-11-02 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain I 1013–1149（137 aa） Fragment：C-TERMINAL DOMAIN, RESIDUES 1013-1149
Chain J 1013–1149（137 aa） Fragment：C-TERMINAL DOMAIN, RESIDUES 1013-1149
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.6；293 K；1.5 UL OF 0.8 MM PROTEIN IN 5 MM BISTRIS, PH 6.5, 200 MM LICL, 4 MM DTT WERE ADDED TO 1.5 UL OF 0.2 M LITHIUM CITRATE, PH 7.6, 20 % (W/V) PEG 3350. THE MIXTURE WAS INCUBATED AT 20 DEGREE CENTIGRADE IN A HANGING DROP SETUP. CRYSTALS GREW IN A FEW DAYS AND WERE CRYO-PROTECTED BY SHORT SOAKING IN 0.2 M LITHIUM CITRATE, PH 7.6, 20 % (W/V) PEG 3350, 30 % (V/V) GLYCEROL.
Resolution 3.20 Å R-free 0.265
2YPZ KSHV LANA (ORF73) C-terminal domain, decameric ring: orthorhombic crystal form Deposited 2012-11-02 Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain C 1013–1149（137 aa） Fragment：C-TERMINAL DOMAIN, RESIDUES 1013-1149
Chain D 1013–1149（137 aa） Fragment：C-TERMINAL DOMAIN, RESIDUES 1013-1149
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.6；293 K；1.5 UL OF 0.8 MM PROTEIN IN 5 MM BISTRIS, PH 6.5, 200 MM LICL, 4 MM DTT WERE ADDED TO 1.5 UL OF 0.2 M LITHIUM CITRATE, PH 7.6, 20 % (W/V) PEG 3350. THE MIXTURE WAS INCUBATED AT 20 DEGREE CENTIGRADE IN A HANGING DROP SETUP. CRYSTALS GREW IN A FEW DAYS AND WERE CRYO-PROTECTED BY SHORT SOAKING IN 0.2 M LITHIUM CITRATE, PH 7.6, 20 % (W/V) PEG 3350, 30 % (V/V) GLYCEROL.
Resolution 3.20 Å R-free 0.265
2YPZ KSHV LANA (ORF73) C-terminal domain, decameric ring: orthorhombic crystal form Deposited 2012-11-02 Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1013–1149（137 aa） Fragment：C-TERMINAL DOMAIN, RESIDUES 1013-1149
Chain B 1013–1149（137 aa） Fragment：C-TERMINAL DOMAIN, RESIDUES 1013-1149
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.6；293 K；1.5 UL OF 0.8 MM PROTEIN IN 5 MM BISTRIS, PH 6.5, 200 MM LICL, 4 MM DTT WERE ADDED TO 1.5 UL OF 0.2 M LITHIUM CITRATE, PH 7.6, 20 % (W/V) PEG 3350. THE MIXTURE WAS INCUBATED AT 20 DEGREE CENTIGRADE IN A HANGING DROP SETUP. CRYSTALS GREW IN A FEW DAYS AND WERE CRYO-PROTECTED BY SHORT SOAKING IN 0.2 M LITHIUM CITRATE, PH 7.6, 20 % (W/V) PEG 3350, 30 % (V/V) GLYCEROL.
Resolution 3.20 Å R-free 0.265
2YPZ KSHV LANA (ORF73) C-terminal domain, decameric ring: orthorhombic crystal form Deposited 2012-11-02 Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain G 1013–1149（137 aa） Fragment：C-TERMINAL DOMAIN, RESIDUES 1013-1149
Chain H 1013–1149（137 aa） Fragment：C-TERMINAL DOMAIN, RESIDUES 1013-1149
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.6；293 K；1.5 UL OF 0.8 MM PROTEIN IN 5 MM BISTRIS, PH 6.5, 200 MM LICL, 4 MM DTT WERE ADDED TO 1.5 UL OF 0.2 M LITHIUM CITRATE, PH 7.6, 20 % (W/V) PEG 3350. THE MIXTURE WAS INCUBATED AT 20 DEGREE CENTIGRADE IN A HANGING DROP SETUP. CRYSTALS GREW IN A FEW DAYS AND WERE CRYO-PROTECTED BY SHORT SOAKING IN 0.2 M LITHIUM CITRATE, PH 7.6, 20 % (W/V) PEG 3350, 30 % (V/V) GLYCEROL.
Resolution 3.20 Å R-free 0.265
2YPZ KSHV LANA (ORF73) C-terminal domain, decameric ring: orthorhombic crystal form Deposited 2012-11-02 Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain E 1013–1149（137 aa） Fragment：C-TERMINAL DOMAIN, RESIDUES 1013-1149
Chain F 1013–1149（137 aa） Fragment：C-TERMINAL DOMAIN, RESIDUES 1013-1149
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.6；293 K；1.5 UL OF 0.8 MM PROTEIN IN 5 MM BISTRIS, PH 6.5, 200 MM LICL, 4 MM DTT WERE ADDED TO 1.5 UL OF 0.2 M LITHIUM CITRATE, PH 7.6, 20 % (W/V) PEG 3350. THE MIXTURE WAS INCUBATED AT 20 DEGREE CENTIGRADE IN A HANGING DROP SETUP. CRYSTALS GREW IN A FEW DAYS AND WERE CRYO-PROTECTED BY SHORT SOAKING IN 0.2 M LITHIUM CITRATE, PH 7.6, 20 % (W/V) PEG 3350, 30 % (V/V) GLYCEROL.
Resolution 3.20 Å R-free 0.265
2YQ0 KSHV LANA (ORF73) C-terminal domain, octameric ring: cubic crystal form Deposited 2012-11-02 Assembly 1 Protein homooligomer Homooligomer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count
Chain A 996–1153（158 aa） Fragment：C-TERMINAL DOMAIN, RESIDUES 996-1153
Not recorded SO4 SULFATE ION × 8 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 2.5；277 K；1 UL OF 1 MM PROTEIN IN 5 MM BISTRIS, PH 6.5, 2 MM DTT WAS ADDED TO 1 UL OF 0.1 M SODIUM CITRATE, PH 2.5, 1.5 M AMMONIUM SULFATE. THE MIXTURE WAS INCUBATED AT 4 DEGREE CENTIGRADE IN A HANGING DROP SETUP. CRYSTALS GREW IN A FEW DAYS AND WERE CRYO-PROTECTED BY SHORT SOAKING IN 0.1 M SODIUM CITRATE, PH 2.5, 1.5 M AMMONIUM SULFATE, 25% (V/V) GLYCEROL.
Resolution 3.91 Å R-free 0.317
4UZB KSHV LANA (ORF73) C-terminal domain mutant bound to LBS1 DNA (R1039Q, R1040Q, K1055E, K1109A, D1110A, A1121E, K1138S, K1140D, K1141D) Deposited 2014-09-05 Assembly 1 Protein–DNA Homooligomer；Protein × 2 PDB declaration: tetrameric（4） Consistent with all polymers
Chain A 1008–1146（139 aa） Fragment：C-TERMINAL DOMAIN, RESIDUES 1008-1146
Chain B 1008–1146（139 aa） Fragment：C-TERMINAL DOMAIN, RESIDUES 1008-1146
Mutation：R1039Q, R1040Q, K1055E, K1109A, D1110A, A1121E, K1138S, K1140D, K1141D Mutation：R1039Q, R1040Q, K1055E, K1109A, D1110A, A1121E, K1138S, K1140D, K1141D No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.6；297 K；0.9 UL OF 1.60 MM LANA(1008-1146) MUTANT, 0.96 MM DSDNA, 10 MM BISTRIS PH 6.5, 0.9 M NACL, AND 5 MM DTT WERE ADDED TO 0.9 UL OF RESERVOIR SOLUTION CONTAINING 50 MM MES PH 6.6, 27% PEG4000, AND 0.3 M AMMONIUM ACETATE IN A HANGING DROP SETUP. CRYSTALS GREW WITHIN FIVE DAYS AT 24 DEGREES CENTIGRADE.
Resolution 2.87 Å R-free 0.155
4UZC KSHV LANA (ORF73) C-terminal domain, spiral: hexagonal crystal form Deposited 2014-09-05 Assembly 1 Protein homooligomer Homooligomer；Protein × 48 PDB declaration: 48-meric（48） Consistent with protein count
Chain A 1013–1149（137 aa） Fragment：C-TERMINAL DOMAIN, RESIDUES 1013-1149
Chain B 1013–1149（137 aa） Fragment：C-TERMINAL DOMAIN, RESIDUES 1013-1149
Chain C 1013–1149（137 aa） Fragment：C-TERMINAL DOMAIN, RESIDUES 1013-1149
Chain D 1013–1149（137 aa） Fragment：C-TERMINAL DOMAIN, RESIDUES 1013-1149
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；0.4 UL OF 31.5 MG/ML PROTEIN IN 5 MM BISTRIS-CL, 5 MM DTT, PH 6.5 WERE AS SUCH EQUILIBRATED AGAINST A RESERVOIR SOLUTION OF 170 MM LITHIUM ACETATE AND 18% (W/V) PEG3350 IN A SITTING DROP SETUP AT 20 DEGREE CENTIGRADE. AFTER TWO DAYS, CRYSTALS WERE DETACHED FROM THE CARRIER PLASTIC BY ADDING 1 UL OF 2 M AMMONIUM FORMATE.
Resolution 3.70 Å R-free 0.239
5A76 KSHV LANA (ORF73) C-terminal domain, open non-ring conformation: orthorhombic crystal form Deposited 2015-07-02 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain E 1018–1150（133 aa） Fragment：DNA-BINDING DOMAIN, UNP RESIDUES 1018-1150
Chain F 1018–1150（133 aa） Fragment：DNA-BINDING DOMAIN, UNP RESIDUES 1018-1150
Not recorded MG MAGNESIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 3；100 MM CITRIC ACID, PH 3.0, 1200 MM MAGNESIUM CHLORIDE.
Resolution 3.80 Å R-free 0.269
5A76 KSHV LANA (ORF73) C-terminal domain, open non-ring conformation: orthorhombic crystal form Deposited 2015-07-02 Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain C 1018–1150（133 aa） Fragment：DNA-BINDING DOMAIN, UNP RESIDUES 1018-1150
Chain D 1018–1150（133 aa） Fragment：DNA-BINDING DOMAIN, UNP RESIDUES 1018-1150
Not recorded MG MAGNESIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 3；100 MM CITRIC ACID, PH 3.0, 1200 MM MAGNESIUM CHLORIDE.
Resolution 3.80 Å R-free 0.269
5A76 KSHV LANA (ORF73) C-terminal domain, open non-ring conformation: orthorhombic crystal form Deposited 2015-07-02 Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1018–1150（133 aa） Fragment：DNA-BINDING DOMAIN, UNP RESIDUES 1018-1150
Chain B 1018–1150（133 aa） Fragment：DNA-BINDING DOMAIN, UNP RESIDUES 1018-1150
Not recorded MG MAGNESIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 3；100 MM CITRIC ACID, PH 3.0, 1200 MM MAGNESIUM CHLORIDE.
Resolution 3.80 Å R-free 0.269
5A76 KSHV LANA (ORF73) C-terminal domain, open non-ring conformation: orthorhombic crystal form Deposited 2015-07-02 Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain G 1018–1150（133 aa） Fragment：DNA-BINDING DOMAIN, UNP RESIDUES 1018-1150
Chain H 1018–1150（133 aa） Fragment：DNA-BINDING DOMAIN, UNP RESIDUES 1018-1150
Not recorded MG MAGNESIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 3；100 MM CITRIC ACID, PH 3.0, 1200 MM MAGNESIUM CHLORIDE.
Resolution 3.80 Å R-free 0.269
7BCY X-ray structure of WDR5delta24 bound to the Kaposi's sarcoma herpesvirus LANA win motif peptide Deposited 2020-12-21 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain Q 23–32（10 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5.5；294 K；100 mM Bis-Tris pH 5.5, 50 mM (NH4)2SO4, 25% PEG3350
Resolution 1.50 Å R-free 0.227
7BCY X-ray structure of WDR5delta24 bound to the Kaposi's sarcoma herpesvirus LANA win motif peptide Deposited 2020-12-21 Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain P 23–32（10 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5.5；294 K；100 mM Bis-Tris pH 5.5, 50 mM (NH4)2SO4, 25% PEG3350
Resolution 1.50 Å R-free 0.227

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.