Current Protein Identity:Q7Z5K2
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 4K6J Human cohesin inhibitor WapL Deposited 2013-04-16 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
631–1190(560 aa)
Fragment:Wapl C-terminal domain (UNP Residues 631-1190)
|
Not recorded | SO4 SULFATE ION × 7 ACT ACETATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7.1;293 K;1.4 M ammonium sulfate, 0.1 M HEPES pH 7.1, 10% glycerol, vapor diffusion, sitting drop, temperature 293K
|
Resolution 2.62 Å R-free 0.237 |
| 4K6J Human cohesin inhibitor WapL Deposited 2013-04-16 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
631–1190(560 aa)
Fragment:Wapl C-terminal domain (UNP Residues 631-1190)
|
Not recorded | SO4 SULFATE ION × 6 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7.1;293 K;1.4 M ammonium sulfate, 0.1 M HEPES pH 7.1, 10% glycerol, vapor diffusion, sitting drop, temperature 293K
|
Resolution 2.62 Å R-free 0.237 |
| 5HDT Human cohesin regulator Pds5B bound to a Wapl peptide Deposited 2016-01-05 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain E
44–76(33 aa)
|
Not recorded | IHP INOSITOL HEXAKISPHOSPHATE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7.5;293 K;0.2 M Sodium Citrate and 20% PEG3350 (vol/vol) without buffer or with buffer 0.1 M Bis-Tris propane pH6.5, pH 7.5 or pH 8.5
|
Resolution 2.71 Å R-free 0.253 |
| 9EP3 Structure of the SA2/SCC1/WAPL complex Deposited 2024-03-16 | Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain C
547–568(22 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;291 K;0.06M Morpheus Divalents mix, 0.1M Morpheus buffer system 1, 48% (v/v) Morpheus EOD_P8K
|
Resolution 3.08 Å R-free 0.268 |