Current Protein Identity:Q8IVS2
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 2C2N Structure of human mitochondrial malonyltransferase Deposited 2005-09-29 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
60–375(316 aa)
Fragment:RESIDUES 60-375
|
Not recorded | SO4 SULFATE ION × 6 AE4 3,6,9,12,15-PENTAOXAHEPTADECAN-1-OL × 1 DXE 1,2-DIMETHOXYETHANE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 8.5;293 K;32%PEG4000, 0.25M LI2SO4, 100MM TRIS-HCL, PH8.5, SITTING DROP, 293 K, pH 8.50
|
Resolution 1.55 Å R-free 0.218 |
| 2C2N Structure of human mitochondrial malonyltransferase Deposited 2005-09-29 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
60–375(316 aa)
Fragment:RESIDUES 60-375
|
Not recorded | SO4 SULFATE ION × 2 CL CHLORIDE ION × 1 AE3 2-(2-ETHOXYETHOXY)ETHANOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 8.5;293 K;32%PEG4000, 0.25M LI2SO4, 100MM TRIS-HCL, PH8.5, SITTING DROP, 293 K, pH 8.50
|
Resolution 1.55 Å R-free 0.218 |
| 8CSP Human mitochondrial small subunit assembly intermediate (State A) Deposited 2022-05-13 | Assembly 1 Protein–RNA Heteromer;Protein × 32 PDB declaration: 33-meric(33) Consistent with all polymers |
Chain 8
1–390(390 aa)
|
Not recorded | SF4 IRON/SULFUR CLUSTER × 1 SAM S-ADENOSYLMETHIONINE × 1 K POTASSIUM ION × 4 MG MAGNESIUM ION × 28 FES FE2/S2 (INORGANIC) CLUSTER × 2 ZN ZINC ION × 1 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 GDP GUANOSINE-5'-DIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.66 Å |
| 8CSQ Human mitochondrial small subunit assembly intermediate (State B) Deposited 2022-05-13 | Assembly 1 Protein–RNA Heteromer;Protein × 32 PDB declaration: 33-meric(33) Consistent with all polymers |
Chain 8
1–390(390 aa)
|
Not recorded | SF4 IRON/SULFUR CLUSTER × 1 SAM S-ADENOSYLMETHIONINE × 1 K POTASSIUM ION × 4 MG MAGNESIUM ION × 27 ZN ZINC ION × 1 FES FE2/S2 (INORGANIC) CLUSTER × 2 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 GDP GUANOSINE-5'-DIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.54 Å |
| 8CSR Human mitochondrial small subunit assembly intermediate (State C) Deposited 2022-05-13 | Assembly 1 Protein–RNA Heteromer;Protein × 33 PDB declaration: 34-meric(34) Consistent with all polymers |
Chain 8
1–390(390 aa)
|
Not recorded | SF4 IRON/SULFUR CLUSTER × 1 SAM S-ADENOSYLMETHIONINE × 1 K POTASSIUM ION × 5 MG MAGNESIUM ION × 31 NAD NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 1 ZN ZINC ION × 1 FES FE2/S2 (INORGANIC) CLUSTER × 2 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 GDP GUANOSINE-5'-DIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.54 Å |
| 8CSS Human mitochondrial small subunit assembly intermediate (State D) Deposited 2022-05-13 | Assembly 1 Protein–RNA Heteromer;Protein × 32 PDB declaration: 33-meric(33) Consistent with all polymers |
Chain 8
1–390(390 aa)
|
Not recorded | SF4 IRON/SULFUR CLUSTER × 1 SAM S-ADENOSYLMETHIONINE × 1 K POTASSIUM ION × 7 MG MAGNESIUM ION × 32 NAD NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 1 ZN ZINC ION × 1 FES FE2/S2 (INORGANIC) CLUSTER × 2 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 GDP GUANOSINE-5'-DIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.36 Å |