Current Protein Identity:Q8NW39
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 2LHR Solution structure of Staphylococcus aureus IsdH linker domain Deposited 2011-08-12 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
467–543(77 aa)
Fragment:UNP residues 467-543
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 6;298 K;Ionic strength (raw mmCIF value) 140;Pressure ambient
NMR sample composition
1.1 mM [U-100% 15N] IsdH linker, 20 mM potassium phosphate, 50 mM potassium chloride, 100 uM AEBSF protease inhibitor, 0.01 % sodium azide, 7 % D2O, 93% H2O/7% D2O | 93% H2O/7% D2O
NMR sample composition
1.3 mM [U-100% 13C; U-100% 15N] IsdH linker, 20 mM potassium phosphate, 50 mM potassium chloride, 100 uM AEBSF protease inhibitor, 0.01 % sodium azide, 7 % D2O, 93% H2O/7% D2O | 93% H2O/7% D2O
NMR sample composition
1.3 mM [U-100% 13C; U-100% 15N] IsdH linker, 20 mM potassium phosphate, 50 mM potassium chloride, 100 uM AEBSF protease inhibitor, 0.01 % sodium azide, 100 % D2O, 100% D2O | 100% D2O
|
Resolution not provided |
| 3SZK Crystal Structure of Human metHaemoglobin Complexed with the First NEAT Domain of IsdH from Staphylococcus aureus Deposited 2011-07-19 | Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain F
86–229(144 aa)
Fragment:first NEAT domain
|
Not recorded | HEM PROTOPORPHYRIN IX CONTAINING FE × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7.5;293 K;0.2M potassium thiocyanate, 0.1M Tris-bis propane, 20% PEG 3350 , pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 3.01 Å R-free 0.275 |
| 3SZK Crystal Structure of Human metHaemoglobin Complexed with the First NEAT Domain of IsdH from Staphylococcus aureus Deposited 2011-07-19 | Assembly 2 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain C
86–229(144 aa)
Fragment:first NEAT domain
|
Not recorded | HEM PROTOPORPHYRIN IX CONTAINING FE × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7.5;293 K;0.2M potassium thiocyanate, 0.1M Tris-bis propane, 20% PEG 3350 , pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 3.01 Å R-free 0.275 |
| 4FC3 Crystal Structure of Human Methaemoglobin Complexed with the Second NEAT Domain of IsdH from Staphylococcus aureus Deposited 2012-05-24 | Assembly 1 Protein heterocomplex Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count |
Chain E
321–464(144 aa)
Fragment:Second NEAT domain
|
Not recorded | HEM PROTOPORPHYRIN IX CONTAINING FE × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7.5;293 K;0.2M Sodium formate, 0.1M bis-tris propane, 20% PEG3350, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.26 Å R-free 0.256 |
| 9S3P Human carboxyhemoglobin bound to Staphylococcus aureus IsdH-N2N3 - 3IsdH(alpha2beta):Hbtet complex Deposited 2025-07-24 | Assembly 1 Protein heterocomplex Heteromer;Protein × 7 PDB declaration: heptameric(7) Consistent with protein count |
Chain E
326–665(340 aa)
Chain F
326–665(340 aa)
Chain G
326–665(340 aa)
|
Not recorded | HEM PROTOPORPHYRIN IX CONTAINING FE × 4 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.2
cryo-EM vitrification conditions
Cryogen ETHANE;blot time 3 s
|
Resolution 3.10 Å |
| 9S4F Human carboxyhemoglobin bound to Staphylococcus aureus IsdH-N2N3 - 2IsdH:Hbdim complex - 3DVA component 4 right tail Deposited 2025-07-28 | Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain C
326–665(340 aa)
Chain D
326–665(340 aa)
|
Not recorded | HEM PROTOPORPHYRIN IX CONTAINING FE × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.2
cryo-EM vitrification conditions
Cryogen ETHANE;blot time 3 s
|
Resolution 4.20 Å |
| 9S4I Human carboxyhemoglobin bound to Staphylococcus aureus IsdH-N2N3 - 2IsdH:Hbdim complex - 3DVA component 0 left tail Deposited 2025-07-28 | Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain C
326–665(340 aa)
Chain D
326–665(340 aa)
|
Not recorded | HEM PROTOPORPHYRIN IX CONTAINING FE × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.2
cryo-EM vitrification conditions
Cryogen ETHANE;blot time 3 s
|
Resolution 4.00 Å |
| 9S4J Human carboxyhemoglobin bound to Staphylococcus aureus IsdH-N2N3 - 2IsdH:Hbdim complex - 3DVA component 0 right tail Deposited 2025-07-28 | Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain C
326–665(340 aa)
Chain D
326–665(340 aa)
|
Not recorded | HEM PROTOPORPHYRIN IX CONTAINING FE × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.2
cryo-EM vitrification conditions
Cryogen ETHANE;blot time 3 s
|
Resolution 4.10 Å |
| 9S4K Human carboxyhemoglobin bound to Staphylococcus aureus IsdH-N2N3 - 2IsdH:Hbdim complex - 3DVA component 4 left tail Deposited 2025-07-28 | Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain C
326–665(340 aa)
Chain D
326–665(340 aa)
|
Not recorded | HEM PROTOPORPHYRIN IX CONTAINING FE × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.2
cryo-EM vitrification conditions
Cryogen ETHANE;blot time 3 s
|
Resolution 4.00 Å |
| 9SZW Human carboxyhemoglobin bound to full-length Staphylococcus aureus IsdH - IsdH:Hbdim complex Deposited 2025-10-16 | Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain C
86–665(580 aa)
|
Not recorded | HEM PROTOPORPHYRIN IX CONTAINING FE × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.2
cryo-EM vitrification conditions
Cryogen ETHANE;blot time 3 s
|
Resolution 3.14 Å |