Current Protein Identity:Q8VDU0
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 3RO2 Structures of the LGN/NuMA complex Deposited 2011-04-25 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
22–357(336 aa)
Fragment:TPR domain, UNP residues 22-357
|
Not recorded | GOL GLYCEROL × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7.5;291 K;0.02M MgCl2, 0.1M HEPES pH 7.5, 22% w/v polyacrylic acid 5100 buffer, VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 2.30 Å R-free 0.271 |
| 3RO3 crystal structure of LGN/mInscuteable complex Deposited 2011-04-25 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
198–357(160 aa)
Fragment:UNP residues 198-357
|
Mutation:R236I | GOL GLYCEROL × 1 EOH ETHANOL × 1 CL CHLORIDE ION × 5 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7.5;291 K;1.5M NaCl, 10% Ethanol, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 1.10 Å R-free 0.150 |
| 4G2V Structure complex of LGN binding with FRMPD1 Deposited 2012-07-13 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
22–357(336 aa)
Fragment:TPR domain, UNP residues 22-357
|
Not recorded | GOL GLYCEROL × 8 BTB 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL × 1 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.5;293 K;0.2M Sodium Chloride, 0.1M BISTIS PH6.5, 25% PEG 3350, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.40 Å R-free 0.232 |
| 4G5O Structure of LGN GL4/Galphai3(Q147L) complex Deposited 2012-07-18 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain E
628–653(26 aa)
Fragment:GoLoco 4 (UNP RESIDUES 628-653)
|
Not recorded | GDP GUANOSINE-5'-DIPHOSPHATE × 1 CIT CITRIC ACID × 2 SO4 SULFATE ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 5.6;291 K;0.5M ammonium sulfate, 1.0M lithium sulfate monohydrate, 0.1M sodium citrate tribasic dihydrate, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 2.90 Å R-free 0.244 |
| 4G5O Structure of LGN GL4/Galphai3(Q147L) complex Deposited 2012-07-18 | Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain F
628–653(26 aa)
Fragment:GoLoco 4 (UNP RESIDUES 628-653)
|
Not recorded | GDP GUANOSINE-5'-DIPHOSPHATE × 1 SO4 SULFATE ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 5.6;291 K;0.5M ammonium sulfate, 1.0M lithium sulfate monohydrate, 0.1M sodium citrate tribasic dihydrate, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 2.90 Å R-free 0.244 |
| 4G5O Structure of LGN GL4/Galphai3(Q147L) complex Deposited 2012-07-18 | Assembly 3 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain G
628–653(26 aa)
Fragment:GoLoco 4 (UNP RESIDUES 628-653)
|
Not recorded | GDP GUANOSINE-5'-DIPHOSPHATE × 1 CIT CITRIC ACID × 1 SO4 SULFATE ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 5.6;291 K;0.5M ammonium sulfate, 1.0M lithium sulfate monohydrate, 0.1M sodium citrate tribasic dihydrate, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 2.90 Å R-free 0.244 |
| 4G5O Structure of LGN GL4/Galphai3(Q147L) complex Deposited 2012-07-18 | Assembly 4 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain H
628–653(26 aa)
Fragment:GoLoco 4 (UNP RESIDUES 628-653)
|
Not recorded | GDP GUANOSINE-5'-DIPHOSPHATE × 1 CIT CITRIC ACID × 1 SO4 SULFATE ION × 5 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 5.6;291 K;0.5M ammonium sulfate, 1.0M lithium sulfate monohydrate, 0.1M sodium citrate tribasic dihydrate, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 2.90 Å R-free 0.244 |
| 4G5Q Structure of LGN GL4/Galphai1 complex Deposited 2012-07-18 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain E
628–652(25 aa)
Fragment:GoLoco 4 (UNP RESIDUES 628-652)
|
Not recorded | GDP GUANOSINE-5'-DIPHOSPHATE × 1 SO4 SULFATE ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 5.6;291 K;0.5M ammonium sulfate, 1.0M lithium sulfate monohydrate, 0.1M sodium citrate tribasic dihydrate, pH 5.6 , VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 2.90 Å R-free 0.243 |
| 4G5Q Structure of LGN GL4/Galphai1 complex Deposited 2012-07-18 | Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain F
628–652(25 aa)
Fragment:GoLoco 4 (UNP RESIDUES 628-652)
|
Not recorded | GDP GUANOSINE-5'-DIPHOSPHATE × 1 SO4 SULFATE ION × 4 CIT CITRIC ACID × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 5.6;291 K;0.5M ammonium sulfate, 1.0M lithium sulfate monohydrate, 0.1M sodium citrate tribasic dihydrate, pH 5.6 , VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 2.90 Å R-free 0.243 |
| 4G5Q Structure of LGN GL4/Galphai1 complex Deposited 2012-07-18 | Assembly 3 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain G
628–652(25 aa)
Fragment:GoLoco 4 (UNP RESIDUES 628-652)
|
Not recorded | GDP GUANOSINE-5'-DIPHOSPHATE × 1 SO4 SULFATE ION × 4 CIT CITRIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 5.6;291 K;0.5M ammonium sulfate, 1.0M lithium sulfate monohydrate, 0.1M sodium citrate tribasic dihydrate, pH 5.6 , VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 2.90 Å R-free 0.243 |
| 4G5Q Structure of LGN GL4/Galphai1 complex Deposited 2012-07-18 | Assembly 4 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain H
628–652(25 aa)
Fragment:GoLoco 4 (UNP RESIDUES 628-652)
|
Not recorded | GDP GUANOSINE-5'-DIPHOSPHATE × 1 SO4 SULFATE ION × 5 CIT CITRIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 5.6;291 K;0.5M ammonium sulfate, 1.0M lithium sulfate monohydrate, 0.1M sodium citrate tribasic dihydrate, pH 5.6 , VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 2.90 Å R-free 0.243 |
| 4G5R Structure of LGN GL4/Galphai3 complex Deposited 2012-07-18 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain E
628–652(25 aa)
Fragment:GoLoco 4 (UNP RESIDUES 628-653)
|
Not recorded | GDP GUANOSINE-5'-DIPHOSPHATE × 1 SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 5.6;291 K;0.5M ammonium sulfate, 1.0M lithium sulfate monohydrate, 0.1M sodium citrate tribasic dihydrate, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 3.48 Å R-free 0.253 |
| 4G5R Structure of LGN GL4/Galphai3 complex Deposited 2012-07-18 | Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain F
628–652(25 aa)
Fragment:GoLoco 4 (UNP RESIDUES 628-653)
|
Not recorded | GDP GUANOSINE-5'-DIPHOSPHATE × 1 SO4 SULFATE ION × 1 CIT CITRIC ACID × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 5.6;291 K;0.5M ammonium sulfate, 1.0M lithium sulfate monohydrate, 0.1M sodium citrate tribasic dihydrate, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 3.48 Å R-free 0.253 |
| 4G5R Structure of LGN GL4/Galphai3 complex Deposited 2012-07-18 | Assembly 3 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain G
628–652(25 aa)
Fragment:GoLoco 4 (UNP RESIDUES 628-653)
|
Not recorded | GDP GUANOSINE-5'-DIPHOSPHATE × 1 SO4 SULFATE ION × 1 CIT CITRIC ACID × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 5.6;291 K;0.5M ammonium sulfate, 1.0M lithium sulfate monohydrate, 0.1M sodium citrate tribasic dihydrate, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 3.48 Å R-free 0.253 |
| 4G5R Structure of LGN GL4/Galphai3 complex Deposited 2012-07-18 | Assembly 4 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain Z
628–652(25 aa)
Fragment:GoLoco 4 (UNP RESIDUES 628-653)
|
Not recorded | GDP GUANOSINE-5'-DIPHOSPHATE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 5.6;291 K;0.5M ammonium sulfate, 1.0M lithium sulfate monohydrate, 0.1M sodium citrate tribasic dihydrate, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 3.48 Å R-free 0.253 |
| 4G5S Structure of LGN GL3/Galphai3 complex Deposited 2012-07-18 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain E
594–618(25 aa)
Fragment:GoLoco 3 (UNP RESIDUES 594-618)
|
Not recorded | GDP GUANOSINE-5'-DIPHOSPHATE × 1 CIT CITRIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 5.6;291 K;0.5M ammonium sulfate, 1.0M lithium sulfate monohydrate, 0.1M sodium citrate tribasic dihydrate, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 3.62 Å R-free 0.253 |
| 4G5S Structure of LGN GL3/Galphai3 complex Deposited 2012-07-18 | Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain F
594–618(25 aa)
Fragment:GoLoco 3 (UNP RESIDUES 594-618)
|
Not recorded | GDP GUANOSINE-5'-DIPHOSPHATE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 5.6;291 K;0.5M ammonium sulfate, 1.0M lithium sulfate monohydrate, 0.1M sodium citrate tribasic dihydrate, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 3.62 Å R-free 0.253 |
| 4G5S Structure of LGN GL3/Galphai3 complex Deposited 2012-07-18 | Assembly 3 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain G
594–618(25 aa)
Fragment:GoLoco 3 (UNP RESIDUES 594-618)
|
Not recorded | GDP GUANOSINE-5'-DIPHOSPHATE × 1 CIT CITRIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 5.6;291 K;0.5M ammonium sulfate, 1.0M lithium sulfate monohydrate, 0.1M sodium citrate tribasic dihydrate, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 3.62 Å R-free 0.253 |
| 4G5S Structure of LGN GL3/Galphai3 complex Deposited 2012-07-18 | Assembly 4 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain Z
594–618(25 aa)
Fragment:GoLoco 3 (UNP RESIDUES 594-618)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 5.6;291 K;0.5M ammonium sulfate, 1.0M lithium sulfate monohydrate, 0.1M sodium citrate tribasic dihydrate, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 3.62 Å R-free 0.253 |
| 4JHR An auto-inhibited conformation of LGN reveals a distinct interaction mode between GoLoco motifs and TPR motifs Deposited 2013-03-05 | Assembly 1 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
96–357(262 aa)
Chain A
593–651(59 aa)
Chain B
96–357(262 aa)
Chain B
593–651(59 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION;pH 5.5;291 K;0.2M NaCl, 0.1M Bis-Tris, 25% Polyethylene Glycol 3350, pH 5.5, EVAPORATION, temperature 291K
|
Resolution 2.80 Å R-free 0.311 |
| 7EP7 The complex structure of Gpsm2 and Whirlin Deposited 2021-04-26 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
22–357(336 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;289 K;1.2 M Ammonium tartrate dibasic, 0.1 M Tris, pH 8.8
|
Resolution 2.60 Å R-free 0.283 |