Current Protein Identity:Q8VDU0 New Search
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
3RO2 Structures of the LGN/NuMA complex Deposited 2011-04-25 Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain A 22–357(336 aa) Fragment:TPR domain, UNP residues 22-357
Not recorded GOL GLYCEROL × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 7.5;291 K;0.02M MgCl2, 0.1M HEPES pH 7.5, 22% w/v polyacrylic acid 5100 buffer, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 2.30 Å R-free 0.271
3RO3 crystal structure of LGN/mInscuteable complex Deposited 2011-04-25 Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain A 198–357(160 aa) Fragment:UNP residues 198-357
Mutation:R236I GOL GLYCEROL × 1 EOH ETHANOL × 1 CL CHLORIDE ION × 5 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 7.5;291 K;1.5M NaCl, 10% Ethanol, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 1.10 Å R-free 0.150
4G2V Structure complex of LGN binding with FRMPD1 Deposited 2012-07-13 Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain A 22–357(336 aa) Fragment:TPR domain, UNP residues 22-357
Not recorded GOL GLYCEROL × 8 BTB 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL × 1 CL CHLORIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 6.5;293 K;0.2M Sodium Chloride, 0.1M BISTIS PH6.5, 25% PEG 3350, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.40 Å R-free 0.232
4G5O Structure of LGN GL4/Galphai3(Q147L) complex Deposited 2012-07-18 Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain E 628–653(26 aa) Fragment:GoLoco 4 (UNP RESIDUES 628-653)
Not recorded GDP GUANOSINE-5'-DIPHOSPHATE × 1 CIT CITRIC ACID × 2 SO4 SULFATE ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 5.6;291 K;0.5M ammonium sulfate, 1.0M lithium sulfate monohydrate, 0.1M sodium citrate tribasic dihydrate, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 2.90 Å R-free 0.244
4G5O Structure of LGN GL4/Galphai3(Q147L) complex Deposited 2012-07-18 Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain F 628–653(26 aa) Fragment:GoLoco 4 (UNP RESIDUES 628-653)
Not recorded GDP GUANOSINE-5'-DIPHOSPHATE × 1 SO4 SULFATE ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 5.6;291 K;0.5M ammonium sulfate, 1.0M lithium sulfate monohydrate, 0.1M sodium citrate tribasic dihydrate, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 2.90 Å R-free 0.244
4G5O Structure of LGN GL4/Galphai3(Q147L) complex Deposited 2012-07-18 Assembly 3 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain G 628–653(26 aa) Fragment:GoLoco 4 (UNP RESIDUES 628-653)
Not recorded GDP GUANOSINE-5'-DIPHOSPHATE × 1 CIT CITRIC ACID × 1 SO4 SULFATE ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 5.6;291 K;0.5M ammonium sulfate, 1.0M lithium sulfate monohydrate, 0.1M sodium citrate tribasic dihydrate, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 2.90 Å R-free 0.244
4G5O Structure of LGN GL4/Galphai3(Q147L) complex Deposited 2012-07-18 Assembly 4 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain H 628–653(26 aa) Fragment:GoLoco 4 (UNP RESIDUES 628-653)
Not recorded GDP GUANOSINE-5'-DIPHOSPHATE × 1 CIT CITRIC ACID × 1 SO4 SULFATE ION × 5 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 5.6;291 K;0.5M ammonium sulfate, 1.0M lithium sulfate monohydrate, 0.1M sodium citrate tribasic dihydrate, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 2.90 Å R-free 0.244
4G5Q Structure of LGN GL4/Galphai1 complex Deposited 2012-07-18 Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain E 628–652(25 aa) Fragment:GoLoco 4 (UNP RESIDUES 628-652)
Not recorded GDP GUANOSINE-5'-DIPHOSPHATE × 1 SO4 SULFATE ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 5.6;291 K;0.5M ammonium sulfate, 1.0M lithium sulfate monohydrate, 0.1M sodium citrate tribasic dihydrate, pH 5.6 , VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 2.90 Å R-free 0.243
4G5Q Structure of LGN GL4/Galphai1 complex Deposited 2012-07-18 Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain F 628–652(25 aa) Fragment:GoLoco 4 (UNP RESIDUES 628-652)
Not recorded GDP GUANOSINE-5'-DIPHOSPHATE × 1 SO4 SULFATE ION × 4 CIT CITRIC ACID × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 5.6;291 K;0.5M ammonium sulfate, 1.0M lithium sulfate monohydrate, 0.1M sodium citrate tribasic dihydrate, pH 5.6 , VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 2.90 Å R-free 0.243
4G5Q Structure of LGN GL4/Galphai1 complex Deposited 2012-07-18 Assembly 3 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain G 628–652(25 aa) Fragment:GoLoco 4 (UNP RESIDUES 628-652)
Not recorded GDP GUANOSINE-5'-DIPHOSPHATE × 1 SO4 SULFATE ION × 4 CIT CITRIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 5.6;291 K;0.5M ammonium sulfate, 1.0M lithium sulfate monohydrate, 0.1M sodium citrate tribasic dihydrate, pH 5.6 , VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 2.90 Å R-free 0.243
4G5Q Structure of LGN GL4/Galphai1 complex Deposited 2012-07-18 Assembly 4 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain H 628–652(25 aa) Fragment:GoLoco 4 (UNP RESIDUES 628-652)
Not recorded GDP GUANOSINE-5'-DIPHOSPHATE × 1 SO4 SULFATE ION × 5 CIT CITRIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 5.6;291 K;0.5M ammonium sulfate, 1.0M lithium sulfate monohydrate, 0.1M sodium citrate tribasic dihydrate, pH 5.6 , VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 2.90 Å R-free 0.243
4G5R Structure of LGN GL4/Galphai3 complex Deposited 2012-07-18 Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain E 628–652(25 aa) Fragment:GoLoco 4 (UNP RESIDUES 628-653)
Not recorded GDP GUANOSINE-5'-DIPHOSPHATE × 1 SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 5.6;291 K;0.5M ammonium sulfate, 1.0M lithium sulfate monohydrate, 0.1M sodium citrate tribasic dihydrate, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 3.48 Å R-free 0.253
4G5R Structure of LGN GL4/Galphai3 complex Deposited 2012-07-18 Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain F 628–652(25 aa) Fragment:GoLoco 4 (UNP RESIDUES 628-653)
Not recorded GDP GUANOSINE-5'-DIPHOSPHATE × 1 SO4 SULFATE ION × 1 CIT CITRIC ACID × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 5.6;291 K;0.5M ammonium sulfate, 1.0M lithium sulfate monohydrate, 0.1M sodium citrate tribasic dihydrate, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 3.48 Å R-free 0.253
4G5R Structure of LGN GL4/Galphai3 complex Deposited 2012-07-18 Assembly 3 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain G 628–652(25 aa) Fragment:GoLoco 4 (UNP RESIDUES 628-653)
Not recorded GDP GUANOSINE-5'-DIPHOSPHATE × 1 SO4 SULFATE ION × 1 CIT CITRIC ACID × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 5.6;291 K;0.5M ammonium sulfate, 1.0M lithium sulfate monohydrate, 0.1M sodium citrate tribasic dihydrate, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 3.48 Å R-free 0.253
4G5R Structure of LGN GL4/Galphai3 complex Deposited 2012-07-18 Assembly 4 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain Z 628–652(25 aa) Fragment:GoLoco 4 (UNP RESIDUES 628-653)
Not recorded GDP GUANOSINE-5'-DIPHOSPHATE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 5.6;291 K;0.5M ammonium sulfate, 1.0M lithium sulfate monohydrate, 0.1M sodium citrate tribasic dihydrate, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 3.48 Å R-free 0.253
4G5S Structure of LGN GL3/Galphai3 complex Deposited 2012-07-18 Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain E 594–618(25 aa) Fragment:GoLoco 3 (UNP RESIDUES 594-618)
Not recorded GDP GUANOSINE-5'-DIPHOSPHATE × 1 CIT CITRIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 5.6;291 K;0.5M ammonium sulfate, 1.0M lithium sulfate monohydrate, 0.1M sodium citrate tribasic dihydrate, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 3.62 Å R-free 0.253
4G5S Structure of LGN GL3/Galphai3 complex Deposited 2012-07-18 Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain F 594–618(25 aa) Fragment:GoLoco 3 (UNP RESIDUES 594-618)
Not recorded GDP GUANOSINE-5'-DIPHOSPHATE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 5.6;291 K;0.5M ammonium sulfate, 1.0M lithium sulfate monohydrate, 0.1M sodium citrate tribasic dihydrate, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 3.62 Å R-free 0.253
4G5S Structure of LGN GL3/Galphai3 complex Deposited 2012-07-18 Assembly 3 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain G 594–618(25 aa) Fragment:GoLoco 3 (UNP RESIDUES 594-618)
Not recorded GDP GUANOSINE-5'-DIPHOSPHATE × 1 CIT CITRIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 5.6;291 K;0.5M ammonium sulfate, 1.0M lithium sulfate monohydrate, 0.1M sodium citrate tribasic dihydrate, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 3.62 Å R-free 0.253
4G5S Structure of LGN GL3/Galphai3 complex Deposited 2012-07-18 Assembly 4 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain Z 594–618(25 aa) Fragment:GoLoco 3 (UNP RESIDUES 594-618)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 5.6;291 K;0.5M ammonium sulfate, 1.0M lithium sulfate monohydrate, 0.1M sodium citrate tribasic dihydrate, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 3.62 Å R-free 0.253
4JHR An auto-inhibited conformation of LGN reveals a distinct interaction mode between GoLoco motifs and TPR motifs Deposited 2013-03-05 Assembly 1 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain A 96–357(262 aa)
Chain A 593–651(59 aa)
Chain B 96–357(262 aa)
Chain B 593–651(59 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION;pH 5.5;291 K;0.2M NaCl, 0.1M Bis-Tris, 25% Polyethylene Glycol 3350, pH 5.5, EVAPORATION, temperature 291K
Resolution 2.80 Å R-free 0.311
7EP7 The complex structure of Gpsm2 and Whirlin Deposited 2021-04-26 Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain A 22–357(336 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;289 K;1.2 M Ammonium tartrate dibasic, 0.1 M Tris, pH 8.8
Resolution 2.60 Å R-free 0.283