Current Protein Identity:Q8WXE0
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 2KE9 NMR solution structure of the CASKIN SH3 domain Deposited 2009-01-27 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
284–348(65 aa)
Fragment:SH3 domain
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7.8;293 K;Ionic strength (raw mmCIF value) 0.15;Pressure ambient
NMR sample composition
0.6 mM [U-98% 13C; U-98% 15N] caskinSH3-1, 10 mM D2O-2, 0.05 % sodium azide-3, 150 mM sodium chloride-4, 20 mM sodium phosphate-5, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 4IS7 Crystal Structure of the CASKIN2 SAM Domain Tandem Deposited 2013-01-16 | Assembly 1 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
483–633(151 aa)
Fragment:UNP residues 483-633
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7.5;298 K;2.4 M NaF, 15% glycerol, 0.1 M Tris-HCl, 0.5 mM protein, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 2.75 Å R-free 0.267 |
| 5L1M CASKIN2 SAM domain tandem Deposited 2016-07-29 | Assembly 1 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
483–633(151 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7.5;278 K;0.1 M Tris pH 7.5, 2.4 M sodium formate, 5 mM DTT
|
Resolution 2.75 Å R-free 0.265 |
| 7ZW4 Crystal structure of Talin R7R8 domains with Caskin-2 LD-peptide Deposited 2022-05-18 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain B
1178–1202(25 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION;293 K;0.1 M bis-Tris propane pH 7.0, 0.1 M NaBr and 24% PEG3350
|
Resolution 2.72 Å R-free 0.269 |