Current Protein Identity:Q92847 New Search
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
6KO5 Complex structure of Ghrelin receptor with Fab Deposited 2019-08-08 Assembly 1 Insufficient information Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain A 29–346(318 aa)
Not recorded 8QX 6-(4-bromanyl-2-fluoranyl-phenoxy)-2-methyl-3-[[(3~{S})-1-propan-2-ylpiperidin-3-yl]methyl]pyrido[3,2-d]pyrimidin-4-one × 1 X-RAY DIFFRACTION
X-ray crystallization conditions LIPIDIC CUBIC PHASE;293 K;100 mM MES (pH6.6-7.0), 400 mM potassium acetate and 36-40% polyethylene glycol (PEG) 300.
Resolution 3.30 Å R-free 0.258
7F83 Crystal Structure of a receptor in Complex with inverse agonist Deposited 2021-07-01 Assembly 1 Insufficient information Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain A 35–243(209 aa)
Chain A 253–342(90 aa)
Chain B 35–243(209 aa)
Chain B 253–342(90 aa)
Mutation:T130K,N188Q,M1012W,H1107I,R1111L Mutation:T130K,N188Q,M1012W,H1107I,R1111L Mutation:T130K,N188Q,M1012W,H1107I,R1111L Mutation:T130K,N188Q,M1012W,H1107I,R1111L OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 6 1KQ 2-(2-methylimidazo[2,1-b][1,3]thiazol-6-yl)-1-[2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone × 2 X-RAY DIFFRACTION
X-ray crystallization conditions LIPIDIC CUBIC PHASE;pH 7;293.15 K;100mM HEPES, pH 7.0, 25%-36% PEG300, 80mM - 150mM NH4F
Resolution 2.94 Å R-free 0.265
7NA7 Structures of human ghrelin receptor-Gi complexes with ghrelin and a synthetic agonist Deposited 2021-06-20 Assembly 1 Protein heterocomplex Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain R 1–366(366 aa)
Not recorded CLR CHOLESTEROL × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.70 Å
7NA8 Structures of human ghrelin receptor-Gi complexes with ghrelin and a synthetic agonist Deposited 2021-06-20 Assembly 1 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count
Chain R 1–366(366 aa)
Not recorded 1KD 1-(methanesulfonyl)-1'-(2-methyl-L-alanyl-O-benzyl-D-seryl)-1,2-dihydrospiro[indole-3,4'-piperidine] × 1 CLR CHOLESTEROL × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.70 Å
7W2Z Cryo-EM structure of the ghrelin-bound human ghrelin receptor-Go complex Deposited 2021-11-24 Assembly 1 Insufficient information Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain R 1–366(366 aa)
Not recorded CLR CHOLESTEROL × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.80 Å
8JSR Cryo-EM structure of the anamorelin-bound ghrelin receptor and Gq complex Deposited 2023-06-20 Assembly 1 Protein heterocomplex Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain R 2–366(365 aa)
Not recorded UYI Anamorelin × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.90 Å
9UY3 Anamorelin bound growth hormone secretagogue receptor in complex with Gq Deposited 2025-05-14 Assembly 1 Insufficient information Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count
Chain R 1–366(366 aa)
Not recorded CLR CHOLESTEROL × 2 A1ESD 2-azanyl-N-[(2R)-1-[(3S)-3-[dimethylamino(methyl)carbamoyl]-3-(phenylmethyl)piperidin-1-yl]-3-(1H-indol-3-yl)-1-oxidanylidene-propan-2-yl]-2-methyl-propanamide × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.3
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.52 Å
9V2N Macimorelin bound growth hormone secretagogue receptor in complex with Gq Deposited 2025-05-20 Assembly 1 Insufficient information Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain R 1–366(366 aa)
Not recorded A1EQV Macimorelin × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.3
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.63 Å