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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：Q92888 New Search
7PDB entries
14Biological assembly
15chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
1IAP CRYSTAL STRUCTURE OF P115RHOGEF RGRGS DOMAIN Deposited 2001-03-22 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 42–252（211 aa） Fragment：N-TERMINAL RGS DOMAIN
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 9.5；293 K；PEG 3350, ammonium formate, CHES, pH 9.5, VAPOR DIFFUSION, HANGING DROP, temperature 293.0K
Resolution 1.90 Å R-free 0.275
1SHZ Crystal Structure of the p115RhoGEF rgRGS Domain in A Complex with Galpha(13):Galpha(i1) Chimera Deposited 2004-02-26 Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain C 7–239（233 aa） Fragment：N-terminal RhoGEF RGS (rgRGS) domain of p115RhoGEF (residues 7-239)
Not recorded MG MAGNESIUM ION × 1 ALF TETRAFLUOROALUMINATE ION × 1 GDP GUANOSINE-5'-DIPHOSPHATE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；289 K；Ammonium Sulfate, Tris, Ethylene glycol , pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 289K
Resolution 2.85 Å R-free 0.297
1SHZ Crystal Structure of the p115RhoGEF rgRGS Domain in A Complex with Galpha(13):Galpha(i1) Chimera Deposited 2004-02-26 Assembly 2 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain F 7–239（233 aa） Fragment：N-terminal RhoGEF RGS (rgRGS) domain of p115RhoGEF (residues 7-239)
Not recorded MG MAGNESIUM ION × 1 ALF TETRAFLUOROALUMINATE ION × 1 GDP GUANOSINE-5'-DIPHOSPHATE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；289 K；Ammonium Sulfate, Tris, Ethylene glycol , pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 289K
Resolution 2.85 Å R-free 0.297
1SHZ Crystal Structure of the p115RhoGEF rgRGS Domain in A Complex with Galpha(13):Galpha(i1) Chimera Deposited 2004-02-26 Assembly 3 Insufficient information Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain C 7–239（233 aa） Fragment：N-terminal RhoGEF RGS (rgRGS) domain of p115RhoGEF (residues 7-239)
Chain F 7–239（233 aa） Fragment：N-terminal RhoGEF RGS (rgRGS) domain of p115RhoGEF (residues 7-239)
Not recorded MG MAGNESIUM ION × 2 ALF TETRAFLUOROALUMINATE ION × 2 GDP GUANOSINE-5'-DIPHOSPHATE × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；289 K；Ammonium Sulfate, Tris, Ethylene glycol , pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 289K
Resolution 2.85 Å R-free 0.297
3AB3 Crystal structure of p115RhoGEF RGS domain in complex with G alpha 13 Deposited 2009-11-30 Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 1–233（233 aa） Fragment：N-TERMINAL RGS HOMOLOGY DOMAIN
Not recorded MG MAGNESIUM ION × 1 GDP GUANOSINE-5'-DIPHOSPHATE × 1 ALF TETRAFLUOROALUMINATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；293 K；15% PEG 4000, 0.1M HEPES, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 293K
Resolution 2.40 Å R-free 0.280
3AB3 Crystal structure of p115RhoGEF RGS domain in complex with G alpha 13 Deposited 2009-11-30 Assembly 2 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain D 1–233（233 aa） Fragment：N-TERMINAL RGS HOMOLOGY DOMAIN
Not recorded MG MAGNESIUM ION × 1 GDP GUANOSINE-5'-DIPHOSPHATE × 1 ALF TETRAFLUOROALUMINATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；293 K；15% PEG 4000, 0.1M HEPES, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 293K
Resolution 2.40 Å R-free 0.280
3ODO Crystal Structure of the DH/PH Domains of p115-RhoGEF Deposited 2010-08-11 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 395–766（372 aa） Fragment：DH-PH domain RESIDUES 395-766
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；2.6-2.8M sodium formate, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.90 Å R-free 0.272
3ODO Crystal Structure of the DH/PH Domains of p115-RhoGEF Deposited 2010-08-11 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 395–766（372 aa） Fragment：DH-PH domain RESIDUES 395-766
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；2.6-2.8M sodium formate, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.90 Å R-free 0.272
3ODW Crystal Structure of the Linker-DH/PH domains of p115-RhoGEF Deposited 2010-08-11 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 240–766（527 aa） Fragment：UNP residues 240-766
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；22-26% PEG 3350, 0.2M ammonium sulfate, and 0.1M NaHEPES, pH 7.2-7.6, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 3.20 Å R-free 0.289
3ODW Crystal Structure of the Linker-DH/PH domains of p115-RhoGEF Deposited 2010-08-11 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 240–766（527 aa） Fragment：UNP residues 240-766
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；22-26% PEG 3350, 0.2M ammonium sulfate, and 0.1M NaHEPES, pH 7.2-7.6, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 3.20 Å R-free 0.289
3ODX Crystal Structure of an N-terminally Truncated Linker-DH/PH Domains of p115-RhoGEF Deposited 2010-08-12 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 353–766（414 aa） Fragment：UNP residues 353-766
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；15-18% PEG 3350, 0.2M sodium chloride, and 0.1M NaHEPES, pH 6.2-6.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 3.20 Å R-free 0.274
3ODX Crystal Structure of an N-terminally Truncated Linker-DH/PH Domains of p115-RhoGEF Deposited 2010-08-12 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 353–766（414 aa） Fragment：UNP residues 353-766
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；15-18% PEG 3350, 0.2M sodium chloride, and 0.1M NaHEPES, pH 6.2-6.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 3.20 Å R-free 0.274
3P6A Crystal Structure of the DH/PH domains of p115-RhoGEF (R399E mutant) Deposited 2010-10-11 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 395–766（372 aa） Fragment：UNP residues 377-748
Mutation：R399E No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions 293 K；2.7-3.0M sodium formate, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.50 Å R-free 0.266
3P6A Crystal Structure of the DH/PH domains of p115-RhoGEF (R399E mutant) Deposited 2010-10-11 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 395–766（372 aa） Fragment：UNP residues 377-748
Mutation：R399E No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions 293 K；2.7-3.0M sodium formate, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.50 Å R-free 0.266

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.