Current Protein Identity:Q96F46
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 3JVF Crystal structure of an Interleukin-17 receptor complex Deposited 2009-09-16 | Assembly 1 Other combination Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain C
32–317(286 aa)
Fragment:extracellular domain
|
Non-standard monomer:Yes (specific site not provided by mmCIF) | CA CALCIUM ION × 1 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 5 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 9.2;295 K;PEG6000, 0.1M CAPSO, calcium chloride, pH 9.2, VAPOR DIFFUSION, HANGING DROP, temperature 295K
|
Resolution 3.30 Å R-free 0.256 |
| 4HSA Structure of interleukin 17a in complex with il17ra receptor Deposited 2012-10-29 | Assembly 1 Other combination Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain C
32–317(286 aa)
|
Mutation:N175D, N234D | No recorded non-water small molecule | X-RAY DIFFRACTION | mmCIF provides none of the parsed conditions | Resolution 3.15 Å R-free 0.232 |
| 4HSA Structure of interleukin 17a in complex with il17ra receptor Deposited 2012-10-29 | Assembly 2 Other combination Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain F
32–317(286 aa)
|
Mutation:N175D, N234D | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 | X-RAY DIFFRACTION | mmCIF provides none of the parsed conditions | Resolution 3.15 Å R-free 0.232 |
| 4NUX Structure of receptor A Deposited 2013-12-04 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
376–591(216 aa)
Fragment:SEFIR domain (UNP residues 376-591)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION;pH 6;293 K;0.1M MES, 5%PEG6000, pH 6.0, EVAPORATION, temperature 293K
|
Resolution 2.29 Å R-free 0.242 |
| 5N9B Crystal Structure of unliganded human IL-17RA Deposited 2017-02-24 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
33–318(286 aa)
Fragment:Extracellular domain, UNP rsidues 33-318
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION;pH 7;293 K;Tris-HCl, PEG 2000 MME, lithium sulfate
|
Resolution 1.90 Å R-free 0.234 |
| 5NAN Crystal Structure of human IL-17AF in complex with human IL-17RA Deposited 2017-02-28 | Assembly 1 Other combination Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain B
33–320(288 aa)
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION;pH 7.5;293 K;0.1M HEPES, 15% PEG MME 5,000, 0.05M Ammonium Acetate
|
Resolution 3.30 Å R-free 0.243 |
| 5NAN Crystal Structure of human IL-17AF in complex with human IL-17RA Deposited 2017-02-28 | Assembly 2 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain C
33–320(288 aa)
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION;pH 7.5;293 K;0.1M HEPES, 15% PEG MME 5,000, 0.05M Ammonium Acetate
|
Resolution 3.30 Å R-free 0.243 |
| 7UWL Structure of the IL-25-IL-17RB-IL-17RA ternary complex Deposited 2022-05-03 | Assembly 1 Other combination Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count |
Chain E
33–317(285 aa)
Chain F
33–317(285 aa)
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 14 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.70 Å |
| 7UWM Structure of the IL-17A-IL-17RA binary complex Deposited 2022-05-03 | Assembly 1 Other combination Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count |
Chain C
33–304(272 aa)
Chain F
33–304(272 aa)
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 7 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.50 Å |
| 7UWN Structure of the IL-17A-IL-17RA-IL-17RC ternary complex Deposited 2022-05-03 | Assembly 1 Other combination Heteromer;Protein × 7 PDB declaration: heptameric(7) Consistent with protein count |
Chain C
33–317(285 aa)
Chain F
33–317(285 aa)
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 9 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.01 Å |
| 7ZAN Crystal Structure of human IL-17A in complex with IL-17RA and IL-17RC Deposited 2022-03-22 | Assembly 1 Protein heterocomplex Heteromer;Protein × 8 PDB declaration: octameric(8) Consistent with protein count |
Chain C
33–320(288 aa)
|
Mutation:N49D, N206D, N265D | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 8 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.5;293 K;0.1M MES, 10.0% PEG DME 500
|
Resolution 5.06 Å R-free 0.353 |
| 9OT1 Helical assembly of the IL-17RA/RB/ACT1 complex Deposited 2025-05-26 | Assembly 1 Insufficient information Heteromer;Protein × 19 PDB declaration: 19-meric(19) Consistent with protein count |
Chain A
361–866(506 aa)
Chain B
361–866(506 aa)
Chain C
361–866(506 aa)
Chain D
361–866(506 aa)
|
Not recorded | ZN ZINC ION × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen NITROGEN
|
Resolution 3.00 Å |