Current Protein Identity:Q96F46 New Search
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
3JVF Crystal structure of an Interleukin-17 receptor complex Deposited 2009-09-16 Assembly 1 Other combination Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain C 32–317(286 aa) Fragment:extracellular domain
Non-standard monomer:Yes (specific site not provided by mmCIF) CA CALCIUM ION × 1 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 5 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 9.2;295 K;PEG6000, 0.1M CAPSO, calcium chloride, pH 9.2, VAPOR DIFFUSION, HANGING DROP, temperature 295K
Resolution 3.30 Å R-free 0.256
4HSA Structure of interleukin 17a in complex with il17ra receptor Deposited 2012-10-29 Assembly 1 Other combination Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain C 32–317(286 aa)
Mutation:N175D, N234D No recorded non-water small molecule X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 3.15 Å R-free 0.232
4HSA Structure of interleukin 17a in complex with il17ra receptor Deposited 2012-10-29 Assembly 2 Other combination Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain F 32–317(286 aa)
Mutation:N175D, N234D NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 3.15 Å R-free 0.232
4NUX Structure of receptor A Deposited 2013-12-04 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 376–591(216 aa) Fragment:SEFIR domain (UNP residues 376-591)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION;pH 6;293 K;0.1M MES, 5%PEG6000, pH 6.0, EVAPORATION, temperature 293K
Resolution 2.29 Å R-free 0.242
5N9B Crystal Structure of unliganded human IL-17RA Deposited 2017-02-24 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 33–318(286 aa) Fragment:Extracellular domain, UNP rsidues 33-318
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION;pH 7;293 K;Tris-HCl, PEG 2000 MME, lithium sulfate
Resolution 1.90 Å R-free 0.234
5NAN Crystal Structure of human IL-17AF in complex with human IL-17RA Deposited 2017-02-28 Assembly 1 Other combination Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain B 33–320(288 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION;pH 7.5;293 K;0.1M HEPES, 15% PEG MME 5,000, 0.05M Ammonium Acetate
Resolution 3.30 Å R-free 0.243
5NAN Crystal Structure of human IL-17AF in complex with human IL-17RA Deposited 2017-02-28 Assembly 2 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain C 33–320(288 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION;pH 7.5;293 K;0.1M HEPES, 15% PEG MME 5,000, 0.05M Ammonium Acetate
Resolution 3.30 Å R-free 0.243
7UWL Structure of the IL-25-IL-17RB-IL-17RA ternary complex Deposited 2022-05-03 Assembly 1 Other combination Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain E 33–317(285 aa)
Chain F 33–317(285 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 14 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.70 Å
7UWM Structure of the IL-17A-IL-17RA binary complex Deposited 2022-05-03 Assembly 1 Other combination Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain C 33–304(272 aa)
Chain F 33–304(272 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 7 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.50 Å
7UWN Structure of the IL-17A-IL-17RA-IL-17RC ternary complex Deposited 2022-05-03 Assembly 1 Other combination Heteromer;Protein × 7 PDB declaration: heptameric(7) Consistent with protein count
Chain C 33–317(285 aa)
Chain F 33–317(285 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 9 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.01 Å
7ZAN Crystal Structure of human IL-17A in complex with IL-17RA and IL-17RC Deposited 2022-03-22 Assembly 1 Protein heterocomplex Heteromer;Protein × 8 PDB declaration: octameric(8) Consistent with protein count
Chain C 33–320(288 aa)
Mutation:N49D, N206D, N265D NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 8 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 6.5;293 K;0.1M MES, 10.0% PEG DME 500
Resolution 5.06 Å R-free 0.353
9OT1 Helical assembly of the IL-17RA/RB/ACT1 complex Deposited 2025-05-26 Assembly 1 Insufficient information Heteromer;Protein × 19 PDB declaration: 19-meric(19) Consistent with protein count
Chain A 361–866(506 aa)
Chain B 361–866(506 aa)
Chain C 361–866(506 aa)
Chain D 361–866(506 aa)
Not recorded ZN ZINC ION × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen NITROGEN
Resolution 3.00 Å