Current Protein Identity:Q9BTU6
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 4HND Crystal structure of the catalytic domain of Selenomethionine substituted human PI4KIIalpha in complex with ADP Deposited 2012-10-19 | Assembly 1 Protein homooligomer Homooligomer;Protein × 16 PDB declaration: hexadecameric(16) Consistent with protein count |
Chain A
78–453(376 aa)
Fragment:residues 78-453
Chain B
78–453(376 aa)
Fragment:residues 78-453
|
Mutation:C174S, C175S, C177S, C178S Non-standard monomer:Yes (specific site not provided by mmCIF) Mutation:C174S, C175S, C177S, C178S Non-standard monomer:Yes (specific site not provided by mmCIF) | ADP ADENOSINE-5'-DIPHOSPHATE × 16 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 5.8;289 K;0.1 M citric acid, 150 mM sodium chloride, 1 mM dithiothreitol, 20 mM magnesium chloride, 18% PEG400, 20 mM hexaethylene glycol monooctyl ether (C8E6), pH 5.8, VAPOR DIFFUSION, HANGING DROP, temperature 289K
|
Resolution 3.20 Å R-free 0.238 |
| 4HNE Crystal structure of the catalytic domain of human type II alpha Phosphatidylinositol 4-kinase (PI4KIIalpha) in complex with ADP Deposited 2012-10-19 | Assembly 1 Protein homooligomer Homooligomer;Protein × 16 PDB declaration: hexadecameric(16) Consistent with protein count |
Chain A
78–453(376 aa)
Fragment:residues 78-453
Chain B
78–453(376 aa)
Fragment:residues 78-453
|
Mutation:C174S, C175S, C177S, C178S Mutation:C174S, C175S, C177S, C178S | ADP ADENOSINE-5'-DIPHOSPHATE × 16 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 5.8;289 K;0.1 M citric acid, 150 mM sodium chloride, 1 mM dithiothreitol, 20 mM magnesium chloride, 18% PEG400, 20 mM hexaethylene glycol monooctyl ether (C8E6), pH 5.8, VAPOR DIFFUSION, HANGING DROP, temperature 289K
|
Resolution 2.95 Å R-free 0.251 |
| 4PLA Crystal structure of phosphatidyl inositol 4-kinase II alpha in complex with ATP Deposited 2014-05-16 | Assembly 1 Insufficient information Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
76–172(97 aa)
Chain A
180–468(289 aa)
|
Not recorded | ATP ADENOSINE-5'-TRIPHOSPHATE × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;293 K;8% PEG 4000, 150 mM (NH4)2SO4, 100 mM MES, pH = 6.5, 10 mM betaine
|
Resolution 2.77 Å R-free 0.251 |
| 4YC4 Crystal structure of phosphatidyl inositol 4-kinase II alpha in complex with nucleotide analog Deposited 2015-02-19 | Assembly 1 Insufficient information Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
76–172(97 aa)
Chain A
180–468(289 aa)
|
Not recorded | M59 [(1S,3S,4S)-3-(6-amino-9H-purin-9-yl)bicyclo[2.2.1]hept-1-yl]methanol × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;291 K;100 mM HEPES pH = 7.0, 10% w/v PEG 4000, 10% v/v 2-propanol
|
Resolution 2.58 Å R-free 0.256 |
| 5EUT Crystal structure of phosphatidyl inositol 4-kinase II alpha in the apo state Deposited 2015-11-19 | Assembly 1 Insufficient information Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
76–172(97 aa)
Chain A
179–468(290 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;291 K;12.5% w/v PEG 1000, 12.5% w/v PEG 3350, 12.5% v/v MPD, 0.1 M bicine/Trizma base pH 8.5
|
Resolution 2.80 Å R-free 0.289 |
| 5I0N PI4K IIalpha bound to calcium Deposited 2016-02-04 | Assembly 1 Insufficient information Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
76–172(97 aa)
Chain A
180–468(289 aa)
|
Not recorded | ATP ADENOSINE-5'-TRIPHOSPHATE × 2 CA CALCIUM ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;295 K;12.5% w/v PEG 1000, 12.5% w/v PEG 3350, 12.5% v/v MPD, 0.1 M bicine/Trizma base pH 8.5
|
Resolution 2.28 Å R-free 0.258 |