Current Protein Identity:Q9GV45 New Search
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
5B0U Crystal structure of the mutated 19 kDa protein of Oplophorus luciferase (nanoKAZ) Deposited 2015-11-04 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 28–196(169 aa)
Mutation:A4E, Q11R, Q18L, L27V, A33N, K43R, V44I, A54I, F68D, L72Q, M75K,I90V, P115E, Q124K, Y138I, N166R No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;293 K;1.1 M di-ammonium tartrate
Resolution 1.71 Å R-free 0.226
5B0U Crystal structure of the mutated 19 kDa protein of Oplophorus luciferase (nanoKAZ) Deposited 2015-11-04 Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain B 28–196(169 aa)
Mutation:A4E, Q11R, Q18L, L27V, A33N, K43R, V44I, A54I, F68D, L72Q, M75K,I90V, P115E, Q124K, Y138I, N166R No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;293 K;1.1 M di-ammonium tartrate
Resolution 1.71 Å R-free 0.226
5IBO 1.95A resolution structure of NanoLuc luciferase Deposited 2016-02-22 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 28–196(169 aa) Fragment:Full Length
Mutation:A4E, Q11R, Q18L, L27V, A33N, K43R, V44I, A54I, F68D, L72Q, M75K, I90V, P115E, Q124K, Y138I, N166R DKA DECANOIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;293 K;20% (w/v) PEG 3350, 200 mM ammonium nitrate
Resolution 1.95 Å R-free 0.250
5IBO 1.95A resolution structure of NanoLuc luciferase Deposited 2016-02-22 Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain B 28–196(169 aa) Fragment:Full Length
Mutation:A4E, Q11R, Q18L, L27V, A33N, K43R, V44I, A54I, F68D, L72Q, M75K, I90V, P115E, Q124K, Y138I, N166R DKA DECANOIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;293 K;20% (w/v) PEG 3350, 200 mM ammonium nitrate
Resolution 1.95 Å R-free 0.250
7SNR 2.00A Resolution Structure of NanoLuc Luciferase Deposited 2021-10-28 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 28–196(169 aa)
Mutation:A4E, Q11R, Q18L, L27V, A33N, K43R, V44I, A54I, F68D, L72Q, M75K, I90V, P115E, Q124K, Y138I, N166R Non-standard monomer:Yes (specific site not provided by mmCIF) ACT ACETATE ION × 2 FLC CITRATE ANION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 4.6;291 K;1.0 M ammonium citrate dibasic, 0.1 M sodium acetate trihydrate
Resolution 2.00 Å R-free 0.213
7SNR 2.00A Resolution Structure of NanoLuc Luciferase Deposited 2021-10-28 Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain B 28–196(169 aa)
Mutation:A4E, Q11R, Q18L, L27V, A33N, K43R, V44I, A54I, F68D, L72Q, M75K, I90V, P115E, Q124K, Y138I, N166R Non-standard monomer:Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 4.6;291 K;1.0 M ammonium citrate dibasic, 0.1 M sodium acetate trihydrate
Resolution 2.00 Å R-free 0.213
7SNS 1.55A Resolution Structure of NanoLuc Luciferase Deposited 2021-10-28 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 28–196(169 aa)
Mutation:A4E, Q11R, Q18L, L27V, A33N, K43R, V44I, A54I, F68D, L72Q, M75K, I90V, P115E, Q124K, Y138I, N166R ACT ACETATE ION × 6 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;291 K;2.8 M Sodium acetate trihydrate, 0.1 M BIS-TRIS propane
Resolution 1.55 Å R-free 0.189
7SNS 1.55A Resolution Structure of NanoLuc Luciferase Deposited 2021-10-28 Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain B 28–196(169 aa)
Mutation:A4E, Q11R, Q18L, L27V, A33N, K43R, V44I, A54I, F68D, L72Q, M75K, I90V, P115E, Q124K, Y138I, N166R ACT ACETATE ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;291 K;2.8 M Sodium acetate trihydrate, 0.1 M BIS-TRIS propane
Resolution 1.55 Å R-free 0.189
7SNS 1.55A Resolution Structure of NanoLuc Luciferase Deposited 2021-10-28 Assembly 3 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain C 28–196(169 aa)
Mutation:A4E, Q11R, Q18L, L27V, A33N, K43R, V44I, A54I, F68D, L72Q, M75K, I90V, P115E, Q124K, Y138I, N166R ACT ACETATE ION × 5 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;291 K;2.8 M Sodium acetate trihydrate, 0.1 M BIS-TRIS propane
Resolution 1.55 Å R-free 0.189
7SNS 1.55A Resolution Structure of NanoLuc Luciferase Deposited 2021-10-28 Assembly 4 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain D 28–196(169 aa)
Mutation:A4E, Q11R, Q18L, L27V, A33N, K43R, V44I, A54I, F68D, L72Q, M75K, I90V, P115E, Q124K, Y138I, N166R ACT ACETATE ION × 5 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;291 K;2.8 M Sodium acetate trihydrate, 0.1 M BIS-TRIS propane
Resolution 1.55 Å R-free 0.189
7SNT 2.20A Resolution Structure of NanoLuc Luciferase with Bound Substrate Analog 3-methoxy-furimazine Deposited 2021-10-28 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 28–196(169 aa)
Mutation:A4E, Q11R, Q18L, L27V, A33N, K43R, V44I, A54I, F68D, L72Q, M75K, I90V, P115E, Q124K, Y138I, N166R 9Z5 (4S)-8-benzyl-2-[(furan-2-yl)methyl]-3-methoxy-6-phenylimidazo[1,2-a]pyrazine × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;291 K;1.0 M sodium citrate dibasic, 0.1 M Tris, 0.2 M NaCl
Resolution 2.20 Å R-free 0.264
7SNT 2.20A Resolution Structure of NanoLuc Luciferase with Bound Substrate Analog 3-methoxy-furimazine Deposited 2021-10-28 Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain B 28–196(169 aa)
Mutation:A4E, Q11R, Q18L, L27V, A33N, K43R, V44I, A54I, F68D, L72Q, M75K, I90V, P115E, Q124K, Y138I, N166R No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;291 K;1.0 M sodium citrate dibasic, 0.1 M Tris, 0.2 M NaCl
Resolution 2.20 Å R-free 0.264
7SNW 1.80A Resolution Structure of NanoLuc Luciferase with Bound Inhibitor PC 16026576 Deposited 2021-10-28 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 28–196(169 aa)
Mutation:A4E, Q11R, Q18L, L27V, A33N, K43R, V44I, A54I, F68D, L72Q, M75K, I90V, P115E, Q124K, Y138I, N166R MG MAGNESIUM ION × 1 SO4 SULFATE ION × 3 9YR 2-(methoxycarbonyl)thiophene-3-sulfonic acid × 1 9Y4 N-[(4-methylphenyl)methyl]-N~2~-phenylglycinamide × 1 GOL GLYCEROL × 1 CL CHLORIDE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;291 K;1.8 M Magnesium Sulfate, 0.1 M Bis-Tris Propane
Resolution 1.80 Å R-free 0.175
7SNW 1.80A Resolution Structure of NanoLuc Luciferase with Bound Inhibitor PC 16026576 Deposited 2021-10-28 Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain B 28–196(169 aa)
Mutation:A4E, Q11R, Q18L, L27V, A33N, K43R, V44I, A54I, F68D, L72Q, M75K, I90V, P115E, Q124K, Y138I, N166R MG MAGNESIUM ION × 1 SO4 SULFATE ION × 1 9YR 2-(methoxycarbonyl)thiophene-3-sulfonic acid × 1 9Y4 N-[(4-methylphenyl)methyl]-N~2~-phenylglycinamide × 1 GOL GLYCEROL × 2 CL CHLORIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;291 K;1.8 M Magnesium Sulfate, 0.1 M Bis-Tris Propane
Resolution 1.80 Å R-free 0.175
7SNW 1.80A Resolution Structure of NanoLuc Luciferase with Bound Inhibitor PC 16026576 Deposited 2021-10-28 Assembly 3 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain C 28–196(169 aa)
Mutation:A4E, Q11R, Q18L, L27V, A33N, K43R, V44I, A54I, F68D, L72Q, M75K, I90V, P115E, Q124K, Y138I, N166R MG MAGNESIUM ION × 1 SO4 SULFATE ION × 1 9YR 2-(methoxycarbonyl)thiophene-3-sulfonic acid × 1 9Y4 N-[(4-methylphenyl)methyl]-N~2~-phenylglycinamide × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;291 K;1.8 M Magnesium Sulfate, 0.1 M Bis-Tris Propane
Resolution 1.80 Å R-free 0.175
7SNX 1.70A Resolution Structure of NanoBiT Complementation Reporter Complex of LgBit and SmBiT Subunits Deposited 2021-10-28 Assembly 1 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain A 28–183(156 aa) Fragment:M-1 to S157
Chain B 185–195(11 aa)
Mutation:;A4E, Q11E, G15A, Q18L, L27V, F31L, A33N, G35A, K43R, V44I, L46R, G51A, A54I, G67A, F68D, G71A, L72Q, M75E, I76V, I90V, H93P, I107L, D108N, P115E, Q124K, Y138I, N144T, L149M, G157S ; Mutation:W161Y, C164F, N166E Non-standard monomer:Yes (specific site not provided by mmCIF) GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 5.6;291 K;1.5 M Na/K Phosphate, 4 (v/v) % 1,3-propanediol
Resolution 1.70 Å R-free 0.178
7SNY 2.10A Resolution Structure of NanoBiT Complementation Reporter Large Subunit LgBiT Deposited 2021-10-28 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 28–183(156 aa) Fragment:M-1 to S157
Mutation:;A4E, Q11E, G15A, Q18L, L27V, F31L, A33N, G35A, K43R, V44I, L46R, G51A, A54I, G67A, F68D, G71A, L72Q, M75E, I76V, I90V, H93P, I107L, D108N, P115E, Q124K, Y138I, N144T, L149M, G157S ; No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 5;291 K;15% (v/v) 2-methyl-2,4-pentanediol, 0.1 M sodium acetate, 2% (w/v) PEG 4000
Resolution 2.10 Å R-free 0.277
8AQ6 NanoLuc luciferase with bound furimamide in surface allosteric site Deposited 2022-08-11 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 28–196(169 aa)
Not recorded GOL GLYCEROL × 1 PG4 TETRAETHYLENE GLYCOL × 3 OXY OXYGEN MOLECULE × 1 CL CHLORIDE ION × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4;293.15 K;200 mM MgCl2, 100 mM KCl, 25 mM Na acetate pH = 4.0, PEG 400
Resolution 1.69 Å R-free 0.183
8AQ6 NanoLuc luciferase with bound furimamide in surface allosteric site Deposited 2022-08-11 Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain B 28–196(169 aa)
Not recorded PG4 TETRAETHYLENE GLYCOL × 1 CL CHLORIDE ION × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4;293.15 K;200 mM MgCl2, 100 mM KCl, 25 mM Na acetate pH = 4.0, PEG 400
Resolution 1.69 Å R-free 0.183
8AQ6 NanoLuc luciferase with bound furimamide in surface allosteric site Deposited 2022-08-11 Assembly 3 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain C 28–196(169 aa)
Not recorded PG4 TETRAETHYLENE GLYCOL × 1 CL CHLORIDE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4;293.15 K;200 mM MgCl2, 100 mM KCl, 25 mM Na acetate pH = 4.0, PEG 400
Resolution 1.69 Å R-free 0.183
8AQ6 NanoLuc luciferase with bound furimamide in surface allosteric site Deposited 2022-08-11 Assembly 4 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain D 28–196(169 aa)
Not recorded CL CHLORIDE ION × 2 PGE TRIETHYLENE GLYCOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4;293.15 K;200 mM MgCl2, 100 mM KCl, 25 mM Na acetate pH = 4.0, PEG 400
Resolution 1.69 Å R-free 0.183
8AQ6 NanoLuc luciferase with bound furimamide in surface allosteric site Deposited 2022-08-11 Assembly 5 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain E 28–196(169 aa)
Not recorded PG4 TETRAETHYLENE GLYCOL × 2 CL CHLORIDE ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4;293.15 K;200 mM MgCl2, 100 mM KCl, 25 mM Na acetate pH = 4.0, PEG 400
Resolution 1.69 Å R-free 0.183
8AQ6 NanoLuc luciferase with bound furimamide in surface allosteric site Deposited 2022-08-11 Assembly 6 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain F 28–196(169 aa)
Not recorded CL CHLORIDE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4;293.15 K;200 mM MgCl2, 100 mM KCl, 25 mM Na acetate pH = 4.0, PEG 400
Resolution 1.69 Å R-free 0.183
8AQ6 NanoLuc luciferase with bound furimamide in surface allosteric site Deposited 2022-08-11 Assembly 7 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain G 28–196(169 aa)
Not recorded CL CHLORIDE ION × 4 NT0 N-(3-Benzyl-5-phenylpyrazin-2-yl)-2-(furan-2-yl)acetamide × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4;293.15 K;200 mM MgCl2, 100 mM KCl, 25 mM Na acetate pH = 4.0, PEG 400
Resolution 1.69 Å R-free 0.183
8AQ6 NanoLuc luciferase with bound furimamide in surface allosteric site Deposited 2022-08-11 Assembly 8 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain H 28–196(169 aa)
Not recorded GOL GLYCEROL × 1 CL CHLORIDE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4;293.15 K;200 mM MgCl2, 100 mM KCl, 25 mM Na acetate pH = 4.0, PEG 400
Resolution 1.69 Å R-free 0.183
8AQH NanoLuc-Y94A luciferase mutant Deposited 2022-08-12 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 28–196(169 aa)
Mutation:Y94A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4;293.15 K;MgCl2, KCl, Na acetate, PEG-400
Resolution 2.80 Å R-free 0.305
8AQH NanoLuc-Y94A luciferase mutant Deposited 2022-08-12 Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain B 28–196(169 aa)
Mutation:Y94A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4;293.15 K;MgCl2, KCl, Na acetate, PEG-400
Resolution 2.80 Å R-free 0.305
8AQI NanoLuc luciferase with bound coelenteramide in surface allosteric site Deposited 2022-08-12 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 28–196(169 aa)
Not recorded CEI N-[3-BENZYL-5-(4-HYDROXYPHENYL)PYRAZIN-2-YL]-2-(4-HYDROXYPHENYL)ACETAMIDE × 1 CL CHLORIDE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4;293.15 K;MgCl2, KCl, Na acetate, PEG-400
Resolution 1.99 Å R-free 0.207
8AQI NanoLuc luciferase with bound coelenteramide in surface allosteric site Deposited 2022-08-12 Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain B 28–196(169 aa)
Not recorded CL CHLORIDE ION × 3 PG4 TETRAETHYLENE GLYCOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4;293.15 K;MgCl2, KCl, Na acetate, PEG-400
Resolution 1.99 Å R-free 0.207
8AQI NanoLuc luciferase with bound coelenteramide in surface allosteric site Deposited 2022-08-12 Assembly 3 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain C 28–196(169 aa)
Not recorded CL CHLORIDE ION × 1 PG4 TETRAETHYLENE GLYCOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4;293.15 K;MgCl2, KCl, Na acetate, PEG-400
Resolution 1.99 Å R-free 0.207
8AQI NanoLuc luciferase with bound coelenteramide in surface allosteric site Deposited 2022-08-12 Assembly 4 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain D 28–196(169 aa)
Not recorded CL CHLORIDE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4;293.15 K;MgCl2, KCl, Na acetate, PEG-400
Resolution 1.99 Å R-free 0.207
8AQI NanoLuc luciferase with bound coelenteramide in surface allosteric site Deposited 2022-08-12 Assembly 5 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain E 28–196(169 aa)
Not recorded CL CHLORIDE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4;293.15 K;MgCl2, KCl, Na acetate, PEG-400
Resolution 1.99 Å R-free 0.207
8AQI NanoLuc luciferase with bound coelenteramide in surface allosteric site Deposited 2022-08-12 Assembly 6 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain F 28–196(169 aa)
Not recorded CL CHLORIDE ION × 2 PG4 TETRAETHYLENE GLYCOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4;293.15 K;MgCl2, KCl, Na acetate, PEG-400
Resolution 1.99 Å R-free 0.207
8AQI NanoLuc luciferase with bound coelenteramide in surface allosteric site Deposited 2022-08-12 Assembly 7 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain G 28–196(169 aa)
Not recorded CEI N-[3-BENZYL-5-(4-HYDROXYPHENYL)PYRAZIN-2-YL]-2-(4-HYDROXYPHENYL)ACETAMIDE × 1 CL CHLORIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4;293.15 K;MgCl2, KCl, Na acetate, PEG-400
Resolution 1.99 Å R-free 0.207
8AQI NanoLuc luciferase with bound coelenteramide in surface allosteric site Deposited 2022-08-12 Assembly 8 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain H 28–196(169 aa)
Not recorded CL CHLORIDE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4;293.15 K;MgCl2, KCl, Na acetate, PEG-400
Resolution 1.99 Å R-free 0.207
8HCQ Cryo-EM structure of endothelin1-bound ETAR-Gq complex Deposited 2022-11-02 Assembly 1 Insufficient information Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain R 27–184(158 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.01 Å
8HCX Cryo-EM structure of Endothelin1-bound ETBR-Gq complex Deposited 2022-11-03 Assembly 1 Insufficient information Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain C 27–184(158 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.50 Å
8HNK CXCR3-DNGi complex activated by CXCL11 Deposited 2022-12-08 Assembly 1 Insufficient information Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain R 27–184(158 aa)
Not recorded CLR CHOLESTEROL × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.01 Å
8HNL CXCR3-DNGi complex activated by PS372424 Deposited 2022-12-08 Assembly 1 Insufficient information Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count
Chain R 27–184(158 aa)
Not recorded CLR CHOLESTEROL × 2 4AI (3S)-N-[(2S)-5-carbamimidamido-1-(cyclohexylmethylamino)-1-oxidanylidene-pentan-2-yl]-2-(4-oxidanylidene-4-phenyl-butanoyl)-3,4-dihydro-1H-isoquinoline-3-carboxamide × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.98 Å
8HNM CXCR3-DNGi complex activated by VUF11222 Deposited 2022-12-08 Assembly 1 Insufficient information Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count
Chain R 27–184(158 aa)
Not recorded CLR CHOLESTEROL × 2 4IE [4-(2-bromophenyl)phenyl]methyl-[[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]methyl]-dimethyl-azanium × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.94 Å
8JPN Cryo-EM structure of succinate receptor bound to cis-epoxysuccinic acid coupling to Gi Deposited 2023-06-12 Assembly 1 Insufficient information Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count
Chain R 28–184(157 aa)
Not recorded U9S (2R,3S)-oxirane-2,3-dicarboxylic acid × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.90 Å
8K2X CXCR3-DNGi complex activated by CXCL10 Deposited 2023-07-14 Assembly 1 Insufficient information Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain R 27–184(158 aa)
Not recorded CLR CHOLESTEROL × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.20 Å
9K07 Cryo-EM structure of the DSO-5a-bound human BRS3-Gq complex Deposited 2024-10-15 Assembly 1 Insufficient information Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain R 28–183(156 aa)
Not recorded A1EL6 [(1~{S})-1-[1,4-dimethoxy-8-nitroso-5-(oxidanylamino)naphthalen-2-yl]-2,2-dimethyl-but-3-enyl] furan-2-carboxylate × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.83 Å
9LWP Cryo-EM structure of the unliganded human BRS3-Gq complex Deposited 2025-02-16 Assembly 1 Insufficient information Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count
Chain R 28–183(156 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.93 Å
9UPU Cryo-EM strucutre of CXCR4 complexed with agonist SDV1a Deposited 2025-04-29 Assembly 1 Insufficient information Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain R 32–183(152 aa)
Not recorded CLR CHOLESTEROL × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.80 Å
9UPV Cryo-EM structure of CXCR4 complexed with agonist SDVX1 Deposited 2025-04-29 Assembly 1 Insufficient information Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain R 32–183(152 aa)
Not recorded CLR CHOLESTEROL × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.70 Å