← Back to search

Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：Q9NPI1 New Search
11PDB entries
20Biological assembly
23chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
2I7K Solution Structure of the Bromodomain of Human BRD7 Protein Deposited 2006-08-31 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 129–236（108 aa） Fragment：bromodomain
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 6.1；293 K；Pressure 1
NMR sample composition 0.6mM BRD7 bromodomain U-15N; 50mM phosphate buffer (pH 6.1), 50mM NaCl, 1mM DTT, 5mM EDTA; 90% H2O, 10% D2O | 90% H2O/10% D2O
NMR sample composition 0.6mM BRD7 bromodomain U-15N,13C; 50mM phosphate buffer (pH 6.1), 50mM NaCl, 1mM DTT, 5mM EDTA; 90% H2O, 10% D2O | 90% H2O/10% D2O
NMR sample composition 0.6mM BRD7 bromodomain U-15N,13C; 50mM phosphate buffer (pH 6.1), 50mM NaCl, 1mM DTT, 5mM EDTA; 99.96% D2O | 99.96% D2O
Resolution not provided
5MQ1 Crystal structure of the BRD7 bromodomain in complex with BI-9564 Deposited 2016-12-19 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 129–239（111 aa）
Not recorded 5U6 4-[4-[(dimethylamino)methyl]-2,5-dimethoxy-phenyl]-2-methyl-2,7-naphthyridin-1-one × 1 ZN ZINC ION × 2 CL CHLORIDE ION × 3 MG MAGNESIUM ION × 1 EDO 1,2-ETHANEDIOL × 11 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；277 K；20% PEG6000, 10%EDO, 0.1 M HEPES pH 7.0, 0.01 M ZnCl2
Resolution 1.50 Å R-free 0.190
6PPA Crystal structure of the unliganded bromodomain of human BRD7 Deposited 2019-07-05 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 130–250（121 aa） Fragment：UNP RESIDUES 130-250
Not recorded PO4 PHOSPHATE ION × 1 EDO 1,2-ETHANEDIOL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；291 K；7.5 MG/ML BRD7, 25MM PHOSPHATE PH 6.9, 25MM AMMONIUM SULPHATE, 0.5MM DTT, 25MM BIS-TRIS PH6.5, 15% PENTAERYTHRYTOL ETHOXYLATE 15/4EO/OH
Resolution 1.77 Å R-free 0.202
6PPA Crystal structure of the unliganded bromodomain of human BRD7 Deposited 2019-07-05 Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 130–250（121 aa） Fragment：UNP RESIDUES 130-250
Not recorded PO4 PHOSPHATE ION × 2 EDO 1,2-ETHANEDIOL × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；291 K；7.5 MG/ML BRD7, 25MM PHOSPHATE PH 6.9, 25MM AMMONIUM SULPHATE, 0.5MM DTT, 25MM BIS-TRIS PH6.5, 15% PENTAERYTHRYTOL ETHOXYLATE 15/4EO/OH
Resolution 1.77 Å R-free 0.202
6V0Q Crystal structure of the bromodomain of human BRD7 bound to TG003 Deposited 2019-11-19 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 130–250（121 aa）
Not recorded EDO 1,2-ETHANEDIOL × 2 PO4 PHOSPHATE ION × 1 CL CHLORIDE ION × 1 EAE (1~{Z})-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylidene)propan-2-one × 1 GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；291 K；0.1 M (NH4)2SO4, 0.05 M Bis-tris (pH 6.5), and 30 % Pentaerythritol ethoxylate
Resolution 1.69 Å R-free 0.218
6V0Q Crystal structure of the bromodomain of human BRD7 bound to TG003 Deposited 2019-11-19 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 130–250（121 aa）
Not recorded EAE (1~{Z})-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylidene)propan-2-one × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；291 K；0.1 M (NH4)2SO4, 0.05 M Bis-tris (pH 6.5), and 30 % Pentaerythritol ethoxylate
Resolution 1.69 Å R-free 0.218
6V0Q Crystal structure of the bromodomain of human BRD7 bound to TG003 Deposited 2019-11-19 Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain C 130–250（121 aa）
Not recorded EDO 1,2-ETHANEDIOL × 1 EAE (1~{Z})-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylidene)propan-2-one × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；291 K；0.1 M (NH4)2SO4, 0.05 M Bis-tris (pH 6.5), and 30 % Pentaerythritol ethoxylate
Resolution 1.69 Å R-free 0.218
6V0Q Crystal structure of the bromodomain of human BRD7 bound to TG003 Deposited 2019-11-19 Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain D 130–250（121 aa）
Not recorded EDO 1,2-ETHANEDIOL × 1 EAE (1~{Z})-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylidene)propan-2-one × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；291 K；0.1 M (NH4)2SO4, 0.05 M Bis-tris (pH 6.5), and 30 % Pentaerythritol ethoxylate
Resolution 1.69 Å R-free 0.218
6V0Q Crystal structure of the bromodomain of human BRD7 bound to TG003 Deposited 2019-11-19 Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 130–250（121 aa）
Chain D 130–250（121 aa）
Not recorded EDO 1,2-ETHANEDIOL × 3 PO4 PHOSPHATE ION × 1 CL CHLORIDE ION × 1 EAE (1~{Z})-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylidene)propan-2-one × 2 GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；291 K；0.1 M (NH4)2SO4, 0.05 M Bis-tris (pH 6.5), and 30 % Pentaerythritol ethoxylate
Resolution 1.69 Å R-free 0.218
6V0Q Crystal structure of the bromodomain of human BRD7 bound to TG003 Deposited 2019-11-19 Assembly 6 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 130–250（121 aa）
Chain C 130–250（121 aa）
Not recorded EDO 1,2-ETHANEDIOL × 1 EAE (1~{Z})-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylidene)propan-2-one × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；291 K；0.1 M (NH4)2SO4, 0.05 M Bis-tris (pH 6.5), and 30 % Pentaerythritol ethoxylate
Resolution 1.69 Å R-free 0.218
6V16 Crystal structure of the bromodomain of human BRD7 bound to TP472 Deposited 2019-11-19 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 130–250（121 aa）
Not recorded QMG 3-(6-acetylpyrrolo[1,2-a]pyrimidin-8-yl)-N-cyclopropyl-4-methylbenzamide × 1 EDO 1,2-ETHANEDIOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；291 K；0.1 M (NH4)2SO4, 0.05 M Bis-tris (pH 6.5), and 30 % Pentaerythritol ethoxylate
Resolution 1.90 Å R-free 0.222
6V16 Crystal structure of the bromodomain of human BRD7 bound to TP472 Deposited 2019-11-19 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 130–250（121 aa）
Not recorded QMG 3-(6-acetylpyrrolo[1,2-a]pyrimidin-8-yl)-N-cyclopropyl-4-methylbenzamide × 1 HEZ HEXANE-1,6-DIOL × 1 GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；291 K；0.1 M (NH4)2SO4, 0.05 M Bis-tris (pH 6.5), and 30 % Pentaerythritol ethoxylate
Resolution 1.90 Å R-free 0.222
6V17 Crystal structure of the bromodomain of human BRD7 bound to I-BRD9 Deposited 2019-11-19 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 130–250（121 aa）
Not recorded CL CHLORIDE ION × 1 H1B N'-[1,1-bis(oxidanylidene)thian-4-yl]-5-ethyl-4-oxidanylidene-7-[3-(trifluoromethyl)phenyl]thieno[3,2-c]pyridine-2-carboximidamide × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；291 K；0.1 M (NH4)2SO4, 0.05 M Bis-tris (pH 6.5), and 30 % Pentaerythritol ethoxylate
Resolution 2.05 Å R-free 0.241
6V17 Crystal structure of the bromodomain of human BRD7 bound to I-BRD9 Deposited 2019-11-19 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 130–250（121 aa）
Not recorded H1B N'-[1,1-bis(oxidanylidene)thian-4-yl]-5-ethyl-4-oxidanylidene-7-[3-(trifluoromethyl)phenyl]thieno[3,2-c]pyridine-2-carboximidamide × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；291 K；0.1 M (NH4)2SO4, 0.05 M Bis-tris (pH 6.5), and 30 % Pentaerythritol ethoxylate
Resolution 2.05 Å R-free 0.241
6V17 Crystal structure of the bromodomain of human BRD7 bound to I-BRD9 Deposited 2019-11-19 Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 130–250（121 aa）
Chain B 130–250（121 aa）
Not recorded CL CHLORIDE ION × 1 H1B N'-[1,1-bis(oxidanylidene)thian-4-yl]-5-ethyl-4-oxidanylidene-7-[3-(trifluoromethyl)phenyl]thieno[3,2-c]pyridine-2-carboximidamide × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；291 K；0.1 M (NH4)2SO4, 0.05 M Bis-tris (pH 6.5), and 30 % Pentaerythritol ethoxylate
Resolution 2.05 Å R-free 0.241
6V1E Crystal structure of the bromodomain of human BRD7 bound to BI7273 Deposited 2019-11-20 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 129–250（122 aa）
Not recorded 5SW 4-[4-[(dimethylamino)methyl]-3,5-dimethoxy-phenyl]-2-methyl-2,7-naphthyridin-1-one × 1 EDO 1,2-ETHANEDIOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；291 K；0.1 M (NH4)2SO4, 0.05 M Bis-tris (pH 6.5), and 30 % Pentaerythritol ethoxylate
Resolution 2.30 Å R-free 0.249
6V1F Crystal structure of the bromodomain of human BRD7 bound to BI9564 Deposited 2019-11-20 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 129–250（122 aa）
Not recorded 5U6 4-[4-[(dimethylamino)methyl]-2,5-dimethoxy-phenyl]-2-methyl-2,7-naphthyridin-1-one × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；291 K；0.05 M (NH4)2SO4, 0.1 M Bis-tris (pH 6.5), and 30 % Pentaerythritol ethoxylate
Resolution 2.00 Å R-free 0.249
6V1H Crystal structure of the bromodomain of human BRD7 bound to bromosporine Deposited 2019-11-20 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 129–250（122 aa）
Not recorded BMF Bromosporine × 1 EDO 1,2-ETHANEDIOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；291 K；0.1 M (NH4)2SO4, 0.05 M Bis-tris (pH 6.5), and 30 % Pentaerythritol ethoxylate
Resolution 1.93 Å R-free 0.235
7VDV The overall structure of human chromatin remodeling PBAF-nucleosome complex Deposited 2021-09-07 Assembly 1 Protein–DNA Heteromer；Protein × 22 PDB declaration: 24-meric（24） Consistent with all polymers
Chain T 1–652（652 aa）
Not recorded BEF BERYLLIUM TRIFLUORIDE ION × 1 MG MAGNESIUM ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.40 Å
7Y8R The nucleosome-bound human PBAF complex Deposited 2022-06-24 Assembly 1 Protein–DNA Heteromer；Protein × 25 PDB declaration: 27-meric（27） Consistent with all polymers
Chain S 1–651（651 aa）
Not recorded ADP ADENOSINE-5'-DIPHOSPHATE × 1 MG MAGNESIUM ION × 1 BEF BERYLLIUM TRIFLUORIDE ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.40 Å

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.