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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：Q9NRY4 New Search
5PDB entries
9Biological assembly
9chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
2K85 p190-A RhoGAP FF1 domain Deposited 2008-09-02 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 267–331（65 aa） Fragment：UNP residues 267-331
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 7.2；285 K；Ionic strength (raw mmCIF value) 0.2；Pressure ambient
NMR sample composition 1 mM p190-A RhoGAP FF1 domain, 50 mM sodium phosphate, 150 mM sodium chloride, 0.5 mM sodium azide, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition 0.5 mM [U-100% 13C; U-100% 15N] p190-A RhoGAP FF1 domain, 50 mM sodium phosphate, 150 mM sodium chloride, 0.5 mM sodium azide, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition 0.5 mM [U-100% 13C; U-100% 15N] p190-A RhoGAP FF1 domain, 50 mM sodium phosphate, 150 mM sodium chloride, 0.5 mM sodium azide, 100% D2O | 100% D2O
Resolution not provided
3C5H Crystal structure of the Ras homolog domain of human GRLF1 (p190RhoGAP) Deposited 2008-01-31 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 13–249（237 aa） Fragment：Ras homolog domain: Residues 13-249
Not recorded MG MAGNESIUM ION × 2 GNP PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER × 1 UNX UNKNOWN LIGAND × 5 X-RAY DIFFRACTION
X-ray crystallization conditions Native crystal, used for model refinement: 26% PEG 4000, 0.1M Tris-HCl, 0.2M Magnesium chloride, 0.1mM DTT, pH 8.0, VAPOR DIFFUSION, SITTING DROP, temperature 291K
X-ray crystallization conditions Seleno-methionine derivative crystal, used for MAD phasing: 33% PEG 4000, 0.1M Tris-HCl, 0.2M Magnesium chloride, 0.1mM DTT, pH 9.0, VAPOR DIFFUSION, SITTING DROP, temperature 291K. A ten-fold excess of GppNHp was added to the protein samples prior to crystallization.
Resolution 1.80 Å R-free 0.247
3FK2 Crystal structure of the RhoGAP domain of human glucocorticoid receptor DNA-binding factor 1 Deposited 2008-12-15 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1212–1439（228 aa） Fragment：UNP residues 1212-1439
Not recorded UNX UNKNOWN LIGAND × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6；291 K；26% PEG 3350, 0.1M Bis-Tris, 0.2M lithium sulfate, 0.001M DTT, 1:100 (w/w) trypsin, pH 6.0, vapor diffusion, sitting drop, temperature 291K
Resolution 2.80 Å R-free 0.273
3FK2 Crystal structure of the RhoGAP domain of human glucocorticoid receptor DNA-binding factor 1 Deposited 2008-12-15 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 1212–1439（228 aa） Fragment：UNP residues 1212-1439
Not recorded UNX UNKNOWN LIGAND × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6；291 K；26% PEG 3350, 0.1M Bis-Tris, 0.2M lithium sulfate, 0.001M DTT, 1:100 (w/w) trypsin, pH 6.0, vapor diffusion, sitting drop, temperature 291K
Resolution 2.80 Å R-free 0.273
3FK2 Crystal structure of the RhoGAP domain of human glucocorticoid receptor DNA-binding factor 1 Deposited 2008-12-15 Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain C 1212–1439（228 aa） Fragment：UNP residues 1212-1439
Not recorded UNX UNKNOWN LIGAND × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6；291 K；26% PEG 3350, 0.1M Bis-Tris, 0.2M lithium sulfate, 0.001M DTT, 1:100 (w/w) trypsin, pH 6.0, vapor diffusion, sitting drop, temperature 291K
Resolution 2.80 Å R-free 0.273
3FK2 Crystal structure of the RhoGAP domain of human glucocorticoid receptor DNA-binding factor 1 Deposited 2008-12-15 Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain D 1212–1439（228 aa） Fragment：UNP residues 1212-1439
Not recorded UNX UNKNOWN LIGAND × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6；291 K；26% PEG 3350, 0.1M Bis-Tris, 0.2M lithium sulfate, 0.001M DTT, 1:100 (w/w) trypsin, pH 6.0, vapor diffusion, sitting drop, temperature 291K
Resolution 2.80 Å R-free 0.273
6WAY C-terminal SH2 domain of p120RasGAP in complex with p190RhoGAP phosphotyrosine peptide Deposited 2020-03-26 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain V 1086–1093（8 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；293 K；1.2 M Sodium citrate tribasic dihydrate, 0.1 M Tris pH 8.5
Resolution 1.50 Å R-free 0.190
8DGQ Crystal structure of p120RasGAP SH2-SH3-SH2 in complex with p190RhoGAP doubly phosphorylated peptide Deposited 2022-06-24 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain U 1083–1111（29 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) MLI MALONATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5；293 K；0.5 M Sodium Malonate pH 5.0, 0.1 M sodium acetate trihydrate salt, 6% PEG 20,000
Resolution 1.95 Å R-free 0.256
8DGQ Crystal structure of p120RasGAP SH2-SH3-SH2 in complex with p190RhoGAP doubly phosphorylated peptide Deposited 2022-06-24 Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain V 1083–1111（29 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) MLI MALONATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5；293 K；0.5 M Sodium Malonate pH 5.0, 0.1 M sodium acetate trihydrate salt, 6% PEG 20,000
Resolution 1.95 Å R-free 0.256

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.