Current Protein Identity:Q9UBP0 New Search
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
3EAB Crystal structure of Spastin MIT in complex with ESCRT III Deposited 2008-08-25 Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain A 112–196(85 aa) Fragment:UNP residues 112 to 196
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;288 K;10% PEG 2000 MME, 0.2 M Ammonia Sulfate, 0.1 M Sodium Acetate, pH 4.6, VAPOR DIFFUSION, HANGING DROP, temperature 288K
Resolution 2.50 Å R-free 0.268
3EAB Crystal structure of Spastin MIT in complex with ESCRT III Deposited 2008-08-25 Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain B 112–196(85 aa) Fragment:UNP residues 112 to 196
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;288 K;10% PEG 2000 MME, 0.2 M Ammonia Sulfate, 0.1 M Sodium Acetate, pH 4.6, VAPOR DIFFUSION, HANGING DROP, temperature 288K
Resolution 2.50 Å R-free 0.268
3EAB Crystal structure of Spastin MIT in complex with ESCRT III Deposited 2008-08-25 Assembly 3 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain C 112–196(85 aa) Fragment:UNP residues 112 to 196
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;288 K;10% PEG 2000 MME, 0.2 M Ammonia Sulfate, 0.1 M Sodium Acetate, pH 4.6, VAPOR DIFFUSION, HANGING DROP, temperature 288K
Resolution 2.50 Å R-free 0.268
3EAB Crystal structure of Spastin MIT in complex with ESCRT III Deposited 2008-08-25 Assembly 4 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain D 112–196(85 aa) Fragment:UNP residues 112 to 196
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;288 K;10% PEG 2000 MME, 0.2 M Ammonia Sulfate, 0.1 M Sodium Acetate, pH 4.6, VAPOR DIFFUSION, HANGING DROP, temperature 288K
Resolution 2.50 Å R-free 0.268
3EAB Crystal structure of Spastin MIT in complex with ESCRT III Deposited 2008-08-25 Assembly 5 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain E 112–196(85 aa) Fragment:UNP residues 112 to 196
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;288 K;10% PEG 2000 MME, 0.2 M Ammonia Sulfate, 0.1 M Sodium Acetate, pH 4.6, VAPOR DIFFUSION, HANGING DROP, temperature 288K
Resolution 2.50 Å R-free 0.268
3EAB Crystal structure of Spastin MIT in complex with ESCRT III Deposited 2008-08-25 Assembly 6 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain F 112–196(85 aa) Fragment:UNP residues 112 to 196
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;288 K;10% PEG 2000 MME, 0.2 M Ammonia Sulfate, 0.1 M Sodium Acetate, pH 4.6, VAPOR DIFFUSION, HANGING DROP, temperature 288K
Resolution 2.50 Å R-free 0.268
3VFD Human spastin AAA domain Deposited 2012-01-09 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 228–616(389 aa) Fragment:AAA domain
Mutation:E442Q SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 6.5;296 K;1.6M (NH3)2SO4, 0.1M MES monohydrate (pH 6.5),10% 1,4-dioxane and 4% benzamidine HCl, 1mM ATP, VAPOR DIFFUSION, HANGING DROP, temperature 296K
Resolution 3.30 Å R-free 0.275
5Z6Q Crystal structure of AAA of Spastin Deposited 2018-01-25 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 229–616(388 aa) Fragment:UNP residues 229-616
Not recorded CL CHLORIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;293 K;3M (NH4)2SO4, 100mM NH4Cl
Resolution 3.00 Å R-free 0.276
5Z6R SPASTIN AAA WITH ATP Deposited 2018-01-25 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 229–616(388 aa) Fragment:UNP RESIDUES 229-616
Mutation:E442Q ATP ADENOSINE-5'-TRIPHOSPHATE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 8.2;293 K;25MM TRIS-HCL, 1MM DTT, 1MM MGCL2, 1MM ATP, 2% PEG 3350, 20MM KSCN
Resolution 3.00 Å R-free 0.279
6PEK Structure of Spastin Hexamer (Subunit A-E) in complex with substrate peptide Deposited 2019-06-20 Assembly 1 Protein heterocomplex Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 87–584(498 aa)
Chain B 87–584(498 aa)
Chain C 87–584(498 aa)
Chain D 87–584(498 aa)
Chain E 87–584(498 aa)
Not recorded ADP ADENOSINE-5'-DIPHOSPHATE × 5 BEF BERYLLIUM TRIFLUORIDE ION × 4 MG MAGNESIUM ION × 4 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.20 Å
6PEN Structure of Spastin Hexamer (whole model) in complex with substrate peptide Deposited 2019-06-20 Assembly 1 Protein heterocomplex Heteromer;Protein × 7 PDB declaration: heptameric(7) Consistent with protein count
Chain A 87–584(498 aa)
Chain B 87–584(498 aa)
Chain C 87–584(498 aa)
Chain D 87–584(498 aa)
Chain E 87–584(498 aa)
Chain F 87–584(498 aa)
Not recorded ADP ADENOSINE-5'-DIPHOSPHATE × 5 BEF BERYLLIUM TRIFLUORIDE ION × 4 MG MAGNESIUM ION × 4 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.20 Å
7S7J Structure of Human SPASTIN-IST1 complex. Deposited 2021-09-16 Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain A 112–195(84 aa)
Not recorded PG4 TETRAETHYLENE GLYCOL × 1 CA CALCIUM ION × 1 PGE TRIETHYLENE GLYCOL × 1 CL CHLORIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 6.5;278 K;40% v/v PEG 300, 100 mM Sodium cacodylate / Hydrochloric acid pH=6.5, 200 mM Calcium Acetate
Resolution 1.15 Å R-free 0.157