Current Protein Identity:Q9Y580 New Search
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
2M8H RRM domain of human RBM7 Deposited 2013-05-21 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 4–94(91 aa) Fragment:unp residues 4-94
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 7;293.15 K;Ionic strength (raw mmCIF value) 200;Pressure ambient
NMR sample composition 0.3 mM [U-99% 13C; U-99% 15N] RBM7, 20 mM BISTRIS, 4 mM beta-mercaptoethanol, 200 mM sodium chloride, 90% H2O/10% D2O | 90% H2O/10% D2O
Resolution not provided
5IQQ Crystal structure of the human RBM7 RRM domain Deposited 2016-03-11 Assembly 1 Protein homooligomer Homooligomer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count
Chain A 1–91(91 aa) Fragment:RNA recognition motif, UNP residues 1-91
Chain B 1–91(91 aa) Fragment:RNA recognition motif, UNP residues 1-91
Chain C 1–91(91 aa) Fragment:RNA recognition motif, UNP residues 1-91
Chain D 1–91(91 aa) Fragment:RNA recognition motif, UNP residues 1-91
Chain E 1–91(91 aa) Fragment:RNA recognition motif, UNP residues 1-91
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION;pH 7.5;292 K;0.1 M Hepes pH 7.5, 150 mM KCl, 1.4 M tri-sodium citrate
Resolution 2.52 Å R-free 0.244
5LXR Structure of the minimal RBM7 - ZCCHC8 Complex Deposited 2016-09-22 Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain A 1–86(86 aa)
Not recorded SM SAMARIUM (III) ION × 3 BR BROMIDE ION × 4 CL CHLORIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 6.5;291.15 K;0.1 M Bis-Tris-Propane pH 6.5 0.2 M NaBr 18% (v/v) PEG3350 7% (w/v) glycerol
Resolution 2.00 Å R-free 0.229
5LXY Structure of the minimal RBM7 - ZCCHC8 Complex Deposited 2016-09-23 Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain A 1–86(86 aa)
Not recorded BR BROMIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 6.5;291.15 K;0.1 M Bis-Tris-Propane 0.2 M NaBr 0.1 M Sodium malonate 20% (w/v) PEG3350
Resolution 2.85 Å R-free 0.300
5LXY Structure of the minimal RBM7 - ZCCHC8 Complex Deposited 2016-09-23 Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain B 1–86(86 aa)
Not recorded BR BROMIDE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 6.5;291.15 K;0.1 M Bis-Tris-Propane 0.2 M NaBr 0.1 M Sodium malonate 20% (w/v) PEG3350
Resolution 2.85 Å R-free 0.300
5LXY Structure of the minimal RBM7 - ZCCHC8 Complex Deposited 2016-09-23 Assembly 3 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain E 1–86(86 aa)
Not recorded BR BROMIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 6.5;291.15 K;0.1 M Bis-Tris-Propane 0.2 M NaBr 0.1 M Sodium malonate 20% (w/v) PEG3350
Resolution 2.85 Å R-free 0.300
5LXY Structure of the minimal RBM7 - ZCCHC8 Complex Deposited 2016-09-23 Assembly 4 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain G 1–86(86 aa)
Not recorded BR BROMIDE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 6.5;291.15 K;0.1 M Bis-Tris-Propane 0.2 M NaBr 0.1 M Sodium malonate 20% (w/v) PEG3350
Resolution 2.85 Å R-free 0.300
5LXY Structure of the minimal RBM7 - ZCCHC8 Complex Deposited 2016-09-23 Assembly 5 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain I 1–86(86 aa)
Not recorded BR BROMIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 6.5;291.15 K;0.1 M Bis-Tris-Propane 0.2 M NaBr 0.1 M Sodium malonate 20% (w/v) PEG3350
Resolution 2.85 Å R-free 0.300
5LXY Structure of the minimal RBM7 - ZCCHC8 Complex Deposited 2016-09-23 Assembly 6 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain K 1–86(86 aa)
Not recorded BR BROMIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 6.5;291.15 K;0.1 M Bis-Tris-Propane 0.2 M NaBr 0.1 M Sodium malonate 20% (w/v) PEG3350
Resolution 2.85 Å R-free 0.300
5LXY Structure of the minimal RBM7 - ZCCHC8 Complex Deposited 2016-09-23 Assembly 7 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain M 1–86(86 aa)
Not recorded BR BROMIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 6.5;291.15 K;0.1 M Bis-Tris-Propane 0.2 M NaBr 0.1 M Sodium malonate 20% (w/v) PEG3350
Resolution 2.85 Å R-free 0.300
7S7B Human Nuclear exosome targeting (NEXT) complex homodimer bound to RNA (substrate 1) Deposited 2021-09-15 Assembly 1 Protein–RNA Heteromer;Protein × 6 PDB declaration: octameric(8) Consistent with all polymers
Chain C 7–86(80 aa)
Chain G 7–86(80 aa)
Not recorded ZN ZINC ION × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 8;20 mM Tris-Cl pH 8.0, 50 mM NaCl, 0.1 mM TCEP supplemented with 0.02% (v/v) IGEPAL CA-630
cryo-EM vitrification conditions Cryogen ETHANE;30 s wait time, blot for 2.5 s before plunging
Resolution 4.06 Å
7S7C Human Nuclear Exosome Targeting (NEXT) complex bound to RNA (substrate 2) Deposited 2021-09-15 Assembly 1 Protein–RNA Heteromer;Protein × 5 PDB declaration: heptameric(7) Consistent with all polymers
Chain C 7–86(80 aa)
Not recorded ZN ZINC ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE;30 s wait time, blot for 2.5 s before plunging
Resolution 3.62 Å