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{
"code": "SASDAG7",
"status": "Published",
"type_of_curve": "Extrapolated to infinite dilution",
"angular_unit": "1/nm",
"project": {
"title": "Molecular mechanism for the action of the anti-CD44 monoclonal antibody MEM-85.",
"publication": {
"title": "Molecular mechanism for the action of the anti-CD44 monoclonal antibody MEM-85.",
"author_list": "Škerlová J, Král V, Kachala M, Fábry M, Bumba L, Svergun DI, Tošner Z, Veverka V, Řezáčová P",
"journal": "J Struct Biol",
"doi": "10.1016/j.jsb.2015.06.005",
"pmid": "26066970",
"published_date": "2015 Aug"
},
"status": "released",
"submitted_date": null,
"released_date": "2015-07-30"
},
"pddf_data": "https://www.sasbdb.org/media/p_of_R_files/SASDAG7.out",
"intensities_data": "https://www.sasbdb.org/media/intensities_files/SASDAG7.dat",
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"pddf_plot": "https://www.sasbdb.org/media/p_of_R_files/pofr_images/SASDAG7_pofr_img.png",
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"experiment": {
"instrument": {
"detector": {
"type": null,
"name": "Pilatus 2M",
"resolution": null
},
"name": "PETRA III",
"city": "DESY; Hamburg",
"country": "Germany",
"beamline_name": "EMBL P12",
"beam_geometry": null,
"type_of_source": "X-ray synchrotron",
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"line_collimation_integrationwidth": null,
"xray_energy": null,
"beam_profile_ah": null,
"beam_profile_al": null
},
"sample": {
"molecule": [
{
"long_name": "Hyaluronate binding domain of CD44 antigen",
"short_name": "CD44 HABD",
"sequence": "SNAASQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTLPTMAQMEKALSIGFE\r\nTCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDL\r\nPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDV\r\n",
"organism": "Homo sapiens",
"uniprot_code": null,
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"oligomerization": "monomer",
"molecular_type": "protein",
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"mw": 17.9,
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"deuteration": null,
"molecule_source": "biological",
"molecule_description": null
},
{
"long_name": "Single-chain Variable Fragment of Antibody MEM-85",
"short_name": "scFv MEM-85",
"sequence": "EVQLQESGPGLVAPSQSLSITCTVSGFSLTNYGVHWVRQPPGKGLEWLGVIWAGGSTNYN\r\nSALMSRLSISKDNSKSQVFLKMNSLQTDDTAMYYCARDGARAMDYWGQGTTVTVSGGGGS\r\nGGGGSGGGGSGGGGSDIVMSQSPSSLAVSVGEKVTVSCKSSQSLLYSSNQKNYLAWYQQK\r\nPGQSPKLLISWASTRESGVPDRFTGSGSGTDFTLTISSVKAEDLAVYYCQQSYSYPWTFG\r\nGGTKLEIKREQKLISEEDLNGTHHHHH",
"organism": "Mus musculus",
"uniprot_code": null,
"uniprot_range_first": null,
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"oligomerization": "monomer",
"molecular_type": "protein",
"uniprot_sequence": null,
"mw": 28.5,
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"complex_state": false,
"deuteration": null,
"molecule_source": "biological",
"molecule_description": null
}
],
"buffer": {
"name": "PBS",
"concentration_unit": null,
"comment": null,
"additive": null,
"concentration": null,
"pka": 7.0,
"ph": 7.4,
"deuteration": null
},
"purity_method": null,
"name": "CD44 HABD scFv MEM-85 complex",
"ext_coefficient": null,
"contrast": null,
"specific_vol": null,
"dry_vol": null,
"absorbption": null,
"deuteration": null,
"mixture": null
},
"contributor": [
{
"affiliation": [
{
"short_name": "EMBL-Hamburg",
"address": "Notkestraße 85, Geb. 25A, 22607 Hamburg, Deutschland, Germany",
"full_name": "European Molecular Biology Laboratory (EMBL) - Hamburg outstation",
"webpage": "http://www.embl-hamburg.de/index.php"
}
],
"contributor_name": "Michael",
"contributor_surname": "Kachala",
"orcid": null
}
],
"concentration_method": null,
"concentration_unit": "mg/ml",
"date": "2013-10-31",
"storage_temperature": 10.0,
"cell_temperature": 10.0,
"exposure_time": 0.05,
"number_of_frames": 20,
"wavelength": 0.12,
"sample_detector_distance": 3.1,
"concentration_min": 1.3,
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"sample_volume": null,
"flow_rate": null,
"s_min": 0.2,
"s_max": 4.488,
"total_exposure_time": null,
"seccolumn": null
},
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"user": 3
}
],
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}
],
"fit_unit": "1/A",
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}
],
"estimated_volume_method": null,
"pddf_software": "ATSAS GNOM",
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"i0_calibration_standard": "BSA",
"description": null,
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"tags": [],
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"experimental_mw": 44.0,
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"guinier_i0_mw": null,
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"porod_mw": null,
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"pddf_i0": 8363.0,
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"intensities_log_log_plot": "SASDAG7_datloglog_img.png",
"symmetry": null,
"last_modified": "2023-06-21T07:56:39.492710+02:00",
"bragg_peak": []
}
