The following content comes directly from the SASBDB entry. Missing values are shown as “—”; SAXSdb does not infer undeclared units.
Every source field is expanded here, including empty values, list members and fields already shown above.
View the complete summary.json source
{
"code": "SASDCR2",
"status": "Published",
"type_of_curve": "Single concentration",
"angular_unit": "1/A",
"project": {
"title": "Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.",
"publication": {
"title": "Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.",
"author_list": "Lambert JP, Picaud S, Fujisawa T, Hou H, Savitsky P, Uusküla-Reimand L, Gupta GD, Abdouni H, Lin ZY, Tucholska M, Knight JDR, Gonzalez-Badillo B, St-Denis N, Newman JA, Stucki M, Pelletier L, Bandeira N, Wilson MD, Filippakopoulos P, Gingras AC",
"journal": "Mol Cell",
"doi": "10.1016/j.molcel.2018.11.006",
"pmid": "30554943",
"published_date": "2018 Dec 13"
},
"status": "released",
"submitted_date": "2017-04-12",
"released_date": "2018-09-10"
},
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"experiment": {
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"name": "Diamond Light Source",
"city": "Didcot",
"country": "UK",
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"long_name": "Bromodomain-containing protein 4",
"short_name": "BRD4",
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"organism": "Homo sapiens",
"uniprot_code": "O60885",
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"oligomerization": "monomer",
"molecular_type": "protein",
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"deuteration": null,
"molecule_source": "biological",
"molecule_description": null
}
],
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"pka": null,
"ph": 7.5,
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},
"purity_method": null,
"name": "Bromodomain-containing protein 4 (BRD4) tandem bromodomains",
"ext_coefficient": null,
"contrast": null,
"specific_vol": null,
"dry_vol": null,
"absorbption": null,
"deuteration": null,
"mixture": null
},
"contributor": [
{
"affiliation": [
{
"short_name": null,
"address": "Oxford, UK",
"full_name": "University of Oxford",
"webpage": "http://www.ox.ac.uk/"
}
],
"contributor_name": "Joseph",
"contributor_surname": "Newman",
"orcid": null
}
],
"concentration_method": null,
"concentration_unit": null,
"date": "2017-01-13",
"storage_temperature": 10.0,
"cell_temperature": 10.0,
"exposure_time": 10.0,
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},
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"software_version": "",
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"bead_radius": 3.75,
"log": null,
"symmetry": "",
"comment": "",
"user": 208
}
],
"fit_unit": "1/A",
"fit_plot": "https://www.sasbdb.org/media/fitting_files/scattering_plots/SASDCR2_fit1_fit_img.png",
"software": "DAMMIN",
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"fit_residual_plot": "SASDCR2_fit1_fitresiduals_img.png",
"fit_data": "https://www.sasbdb.org/media/fitting_files/SASDCR2_fit1.fir",
"fit_log": "https://www.sasbdb.org/media/fitting_files/log_files/brd4-u001-slow.log",
"software_version": "",
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}
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"estimated_volume_method": "DAMMIN",
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"i0_calibration_standard": null,
"description": null,
"experiment_description": "Synchrotron SAXS data from solutions of BRD4 tandem bromodomains in 20 mM HEPES, 150 mM NaCl, 2% glycerol, 0.5 mM TCEP, pH 7.5 were collected on the B21 beam line at the Diamond Light Source (Oxfordshire, UK) using a Pilatus 2M detector at a sample-detector distance of 3.9 m and at a wavelength of λ = 0.1 nm (I(s) vs s, where s = 4πsinθ/λ and 2θ is the scattering angle). In-line continuous flow HPLC-SAXS was employed at 10°C with a sample injection concentration of 13 mg/ml onto a Shodex 404 column. 12 successive 10 second frames were collected through the HPLC-elution peak. The data were normalized to the intensity of the transmitted beam and radially averaged; the scattering of the solvent-blank was subtracted and the different curves underwent single-value decomposition to produce the average-median scattering data displayed in this entry.",
"tags": [],
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"i0_calibration_standard_data": null,
"intensities_log_log_plot": "SASDCR2_datloglog_img.png",
"symmetry": null,
"last_modified": "2019-12-06T13:07:15.624532+01:00",
"bragg_peak": []
}
View the complete manifest.json source
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