查看完整 summary.json 原文
{
"code": "SASDEP4",
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"angular_unit": "1/A",
"project": {
"title": "Mechanism of activating mutations and allosteric drug inhibition of the phosphatase SHP2.",
"publication": {
"title": "Mechanism of activating mutations and allosteric drug inhibition of the phosphatase SHP2.",
"author_list": "Pádua RAP, Sun Y, Marko I, Pitsawong W, Stiller JB, Otten R, Kern D",
"journal": "Nat Commun",
"doi": "10.1038/s41467-018-06814-w",
"pmid": "30375376",
"published_date": "2018 Oct 30"
},
"status": "released",
"submitted_date": "2018-09-14",
"released_date": "2018-11-05"
},
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},
"name": "Stanford Synchrotron Radiation Lightsource (SSRL)",
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{
"long_name": "Tyrosine-protein phosphatase non-receptor type 11 E76K",
"short_name": "SHP2 E76K",
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"organism": "Homo sapiens",
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"oligomerization": "monomer",
"molecular_type": "protein",
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}
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"name": "Protein tyrosine phosphatase SHP2 with E76K activating mutation",
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},
"contributor": [
{
"affiliation": [
{
"short_name": null,
"address": "Chevy Chase, USA",
"full_name": "Howard Hughes Medical Institute, Department of Biochemistry, Brandeis University",
"webpage": "https://www.hhmi.org/"
}
],
"contributor_name": "RIcardo",
"contributor_surname": "Padua",
"orcid": "https://orcid.org/0000-0001-9719-3440"
}
],
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"date": "2016-03-28",
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"description": null,
"experiment_description": "Synchrotron SAXS data from solutions of Protein tyrosine phosphatase SHP2 with E76K activating mutation in 50 mM ADA, 2 mM TCEP, pH 6.5 were collected on the BL4-2 beam line at the Stanford Synchrotron Radiation Lightsource (SSRL; Stanford, CA, USA) using a Rayonix MX225-HE detector at a sample-detector distance of 1.7 m and at a wavelength of λ = 0.1127 nm (l(s) vs s, where s = 4πsinθ/λ, and 2θ is the scattering angle). Solute concentrations ranging between 0.8 and 12.2 mg/ml were measured at 20°C. 10 successive 1 second frames were collected. The data were normalized to the intensity of the transmitted beam and radially averaged; the scattering of the solvent-blank was subtracted. The low angle data collected at lower concentration were merged with the highest concentration high angle data to yield the final composite scattering curve.",
"tags": [],
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"i0_calibration_standard_data": null,
"intensities_log_log_plot": "SASDEP4_datloglog_img.png",
"symmetry": null,
"last_modified": "2019-12-06T13:07:15.624532+01:00",
"bragg_peak": []
}查看完整 manifest.json 原文
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