wild-type human Latency Associated Peptide (LAP)

{
  "code": "SASDFE2",
  "status": "Published",
  "type_of_curve": "Single concentration",
  "angular_unit": "1/A",
  "project": {
    "title": "Structural consequences of transforming growth factor beta-1 activation from near-therapeutic X-ray doses.",
    "publication": {
      "title": "Structural consequences of transforming growth factor beta-1 activation from near-therapeutic X-ray doses.",
      "author_list": "Stachowski T, Grant TD, Snell EH",
      "journal": "J Synchrotron Radiat",
      "doi": "10.1107/S1600577519005113",
      "pmid": "31274418",
      "published_date": "2019 Jul 1"
    },
    "status": "released",
    "submitted_date": "2019-01-29",
    "released_date": "2019-06-19"
  },
  "pddf_data": "https://www.sasbdb.org/media/p_of_R_files/SASDFE2.out",
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  "intensities_kratky_plot": "https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDFE2_kratky_img.png",
  "pddf_plot": "https://www.sasbdb.org/media/p_of_R_files/pofr_images/SASDFE2_pofr_img.png",
  "intensities_guinier_plot": "https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDFE2_guinier_img.png",
  "sascif_data": "https://www.sasbdb.org/media/sascif/sascif_files/SASDFE2.sascif",
  "experiment": {
    "instrument": {
      "detector": {
        "type": null,
        "name": "Pilatus3 X 2M",
        "resolution": 172.0
      },
      "name": "Advanced Light Source (ALS)",
      "city": "Berkeley, CA",
      "country": "USA",
      "beamline_name": "12.3.1 (SIBYLS)",
      "beam_geometry": "",
      "type_of_source": "X-ray synchrotron",
      "point_source": null,
      "line_collimation": null,
      "sample_path_length": null,
      "line_collimation_slitlength": null,
      "line_collimation_integrationwidth": null,
      "xray_energy": null,
      "beam_profile_ah": null,
      "beam_profile_al": null
    },
    "sample": {
      "molecule": [
        {
          "long_name": "Latency Associated Peptide",
          "short_name": "LAP",
          "sequence": "LSTSKTIDMELVKRKRIEAIRGQILSKLRLASPPSQG\r\nEVPPGPLPEAVLALYNSTRDRVAGESAEPEPEPEADYYAKEVTRVLMVETHNEIYDKFKQSTHSIYMFFNTSELREAVPE\r\nPVLLSRAELRLLRLKLKVEQHVELYQKYSNNSWRYLSNRLLAPSDSPEWLSFDVTGVVRQWLSRGGEIEGFRLSAHCSCD\r\nSRDNTLQVDINGFTTGRRGDLATIHGMNRPFLLLMATPLERAQHLQSSRHRAHHHHHH",
          "organism": "Homo sapiens",
          "uniprot_code": "P01137",
          "uniprot_range_first": 30,
          "uniprot_range_last": 278,
          "oligomerization": "dimer",
          "molecular_type": "protein",
          "uniprot_sequence": "MPPSGLRLLLLLLPLLWLLVLTPGRPAAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLA\nSPPSQGEVPPGPLPEAVLALYNSTRDRVAGESAEPEPEPEADYYAKEVTRVLMVETHNEI\nYDKFKQSTHSIYMFFNTSELREAVPEPVLLSRAELRLLRLKLKVEQHVELYQKYSNNSWR\nYLSNRLLAPSDSPEWLSFDVTGVVRQWLSRGGEIEGFRLSAHCSCDSRDNTLQVDINGFT\nTGRRGDLATIHGMNRPFLLLMATPLERAQHLQSSRHRRALDTNYCFSSTEKNCCVRQLYI\nDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQA\nLEPLPIVYYVGRKPKVEQLSNMIVRSCKCS",
          "mw": 29.212,
          "total_mw": 58.424,
          "number_molecules": 2,
          "complex_state": false,
          "deuteration": null,
          "molecule_source": "biological",
          "molecule_description": null
        }
      ],
      "buffer": {
        "name": "phosphate buffered saline",
        "concentration_unit": null,
        "comment": null,
        "additive": null,
        "concentration": null,
        "pka": null,
        "ph": 7.4,
        "deuteration": null
      },
      "purity_method": null,
      "name": "wild-type human Latency Associated Peptide (LAP)",
      "ext_coefficient": null,
      "contrast": null,
      "specific_vol": null,
      "dry_vol": null,
      "absorbption": null,
      "deuteration": null,
      "mixture": null
    },
    "contributor": [
      {
        "affiliation": [
          {
            "short_name": null,
            "address": "New York, USA",
            "full_name": "Hauptman-Woodward Medical Research Institute",
            "webpage": "http://hwi.buffalo.edu/"
          }
        ],
        "contributor_name": "Tim",
        "contributor_surname": "Stachowski",
        "orcid": "https://orcid.org/0000-0002-6097-4857"
      }
    ],
    "concentration_method": null,
    "concentration_unit": null,
    "date": "2018-10-04",
    "storage_temperature": 4.0,
    "cell_temperature": 10.0,
    "exposure_time": 0.1,
    "number_of_frames": 4,
    "wavelength": 0.1127,
    "sample_detector_distance": 2.0,
    "concentration_min": null,
    "concentration_max": 4.5,
    "sample_volume": null,
    "flow_rate": null,
    "s_min": 0.114,
    "s_max": 4.038,
    "total_exposure_time": null,
    "seccolumn": null
  },
  "fits": [],
  "estimated_volume_method": null,
  "pddf_software": "ATSAS GNOM",
  "pddf_software_version": "5.0",
  "i0_calibration_standard": null,
  "description": null,
  "experiment_description": "Synchrotron SAXS data from solutions of wild-type human Latency Associated Peptide (LAP) in phosphate buffered saline, pH 7.4 were collected on the 12.3.1 (SIBYLS) beam line at the Advanced Light Source (ALS; Berkeley, CA, USA) using a Pilatus3 X 2M detector at a sample-detector distance of 2 m and at a wavelength of λ = 0.1127 nm (l(s) vs s, where s = 4πsinθ/λ, and 2θ is the scattering angle). One solute concentration of 4.50 mg/ml was measured at 10°C. Four successive 0.100 second frames were collected. The data were normalized to the intensity of the transmitted beam and radially averaged; the scattering of the solvent-blank was subtracted.",
  "tags": [],
  "intensity_unit": "arbitrary",
  "experimental_mw": 91.0,
  "experimental_mw_error": null,
  "guinier_i0_mw": null,
  "guinier_i0_mw_error": null,
  "porod_mw": 110.0,
  "porod_mw_error": null,
  "pddf_i0": 28.63,
  "pddf_i0_error": null,
  "guinier_i0": 28.17,
  "guinier_i0_error": 0.077,
  "pddf_rg": 4.36,
  "pddf_rg_error": null,
  "guinier_rg": 4.1,
  "guinier_rg_error": 0.018,
  "pddf_dmax": 17.5,
  "pddf_dmax_error": null,
  "porod_volume": 179.0,
  "porod_volume_error": null,
  "estimated_volume": null,
  "estimated_volume_error": null,
  "guinier_point_first": 1,
  "guinier_point_last": 34,
  "pddf_point_first": null,
  "pddf_point_last": null,
  "i0_calibration_standard_data": null,
  "intensities_log_log_plot": "SASDFE2_datloglog_img.png",
  "symmetry": null,
  "last_modified": "2019-12-06T13:07:15.624532+01:00",
  "bragg_peak": []
}

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  "code": "SASDFE2",
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  "started_at": "2026-08-11T13:36:40.376968+00:00",
  "finished_at": "2026-08-11T13:36:49.563543+00:00",
  "source_last_modified": "2019-12-06T13:07:15.624532+01:00",
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