Apolipoprotein E4 (methylated) bound to 12 µg/mL heparin

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  "status": "Published",
  "type_of_curve": "Single concentration",
  "angular_unit": "1/A",
  "project": {
    "title": "Therapeutic approaches to ApoE",
    "publication": {
      "title": "Therapeutic approaches to ApoE",
      "author_list": "Lucas Kraft",
      "journal": "University of Sussex PhD thesis",
      "doi": null,
      "pmid": null,
      "published_date": "2019 April 25"
    },
    "status": "released",
    "submitted_date": "2019-10-25",
    "released_date": "2021-09-27"
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      "detector": {
        "type": null,
        "name": "Pilatus 2M",
        "resolution": null
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      "name": "Diamond Light Source",
      "city": "Didcot",
      "country": "UK",
      "beamline_name": "B21",
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      "type_of_source": "X-ray synchrotron",
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          "long_name": "Apolipoprotein E4",
          "short_name": "ApoE4",
          "sequence": "GPHMKVEQAVETEPEPELRQQTEWQSGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQLTPVAEETRARLSKELQAAQARLGADMEDVRGRLVQYRGEVQAMLGQSTEELRVRLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRAATVGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQQIRLQAEAFQARLKSWFEPLVEDMQRQWAGLVEKVQAAVGTSAAPVPSDNH",
          "organism": "Homo sapiens",
          "uniprot_code": "P02649",
          "uniprot_range_first": 19,
          "uniprot_range_last": 317,
          "oligomerization": "tetramer",
          "molecular_type": "protein",
          "uniprot_sequence": "MKVLWAALLVTFLAGCQAKVEQAVETEPEPELRQQTEWQSGQRWELALGRFWDYLRWVQT\nLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQLTPVAEETRARLSKELQAAQA\nRLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLRKLRKRLLRDADDLQKRLAVY\nQAGAREGAERGLSAIRERLGPLVEQGRVRAATVGSLAGQPLQERAQAWGERLRARMEEMG\nSRTRDRLDEVKEQVAEVRAKLEEQAQQIRLQAEAFQARLKSWFEPLVEDMQRQWAGLVEK\nVQAAVGTSAAPVPSDNH",
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          "complex_state": false,
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          "long_name": "Heparin",
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          "sequence": "(C12H19NO20S3)n",
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      "buffer": {
        "name": "20 mM HEPES, 300 mM NaCl, 1 mM TCEP",
        "concentration_unit": null,
        "comment": null,
        "additive": null,
        "concentration": null,
        "pka": null,
        "ph": 8.0,
        "deuteration": null
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      "purity_method": null,
      "name": "Apolipoprotein E4 (methylated) bound to 12 µg/mL heparin",
      "ext_coefficient": null,
      "contrast": null,
      "specific_vol": null,
      "dry_vol": null,
      "absorbption": null,
      "deuteration": null,
      "mixture": null
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    "contributor": [
      {
        "affiliation": [
          {
            "short_name": null,
            "address": "Brighton, UK",
            "full_name": "University of Sussex",
            "webpage": "http://www.sussex.ac.uk/"
          }
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        "contributor_name": "Lucas",
        "contributor_surname": "Kraft",
        "orcid": ""
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    "concentration_method": null,
    "concentration_unit": null,
    "date": "2018-05-03",
    "storage_temperature": 20.0,
    "cell_temperature": 20.0,
    "exposure_time": 1.0,
    "number_of_frames": 28,
    "wavelength": 0.1,
    "sample_detector_distance": 4.036,
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  "pddf_software_version": "2.8.4",
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  "description": "ApoE4 (methylated) + 12 µg/mL heparin. Molecular weight estimates are inaccurate due to heparin heterogeneity.",
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  "pddf_dmax_error": null,
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  "estimated_volume_error": null,
  "guinier_point_first": 19,
  "guinier_point_last": 77,
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  "i0_calibration_standard_data": null,
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  "symmetry": null,
  "last_modified": "2024-10-07T16:03:00.193031+02:00",
  "bragg_peak": []
}

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