STATIC-SAXS of Trypanosoma cruzi Prolyl Oligopepetidase (TcPOP)

{
  "code": "SASDW33",
  "status": "Published",
  "type_of_curve": "Extrapolated to infinite dilution",
  "angular_unit": "1/A",
  "project": {
    "title": "Cryo-EM led analysis of open and closed conformations of Chagas vaccine candidate TcPOP.",
    "publication": {
      "title": "Cryo-EM led analysis of open and closed conformations of Chagas vaccine candidate TcPOP.",
      "author_list": "Batra S, Olmo F, Ragan TJ, Kaplan M, Calvaresi V, Frank AM, Lancey C, Assadipapari M, Ying C, Struwe WB, Hesketh EL, Kelly JM, Barfod L, Campeotto I",
      "journal": "Nat Commun",
      "doi": "10.1038/s41467-025-62068-3",
      "pmid": "40764299",
      "published_date": "2025 Aug 5"
    },
    "status": "released",
    "submitted_date": "2024-12-07",
    "released_date": "2025-08-07"
  },
  "pddf_data": "https://www.sasbdb.org/media/p_of_R_files/SASDW33.out",
  "intensities_data": "https://www.sasbdb.org/media/intensities_files/SASDW33.dat",
  "intensities_log_plot": "https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDW33_dat_img.png",
  "intensities_kratky_plot": "https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDW33_kratky_img.png",
  "pddf_plot": "https://www.sasbdb.org/media/p_of_R_files/pofr_images/SASDW33_pofr_img.png",
  "intensities_guinier_plot": "https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDW33_guinier_img.png",
  "sascif_data": "https://www.sasbdb.org/media/sascif/sascif_files/SASDW33.sascif",
  "experiment": {
    "instrument": {
      "detector": {
        "type": null,
        "name": "Eiger 4M",
        "resolution": 75.0
      },
      "name": "Diamond Light Source",
      "city": "Didcot",
      "country": "UK",
      "beamline_name": "B21",
      "beam_geometry": null,
      "type_of_source": "X-ray synchrotron",
      "point_source": null,
      "line_collimation": null,
      "sample_path_length": null,
      "line_collimation_slitlength": null,
      "line_collimation_integrationwidth": null,
      "xray_energy": null,
      "beam_profile_ah": null,
      "beam_profile_al": null
    },
    "sample": {
      "molecule": [
        {
          "long_name": "Prolyl endopeptidase",
          "short_name": null,
          "sequence": ">sp|Q71MD6|Q71MD6_TRYCR 80 kDa prolyl oligopeptidase\r\nMRSVYPLARRSMAAYTMHNMTVPEPYDYLEDPENPETKTFVNEQNAFFEEYFASEAELRKKIFESISNSQ\r\nDYPRTSNPSYINGHYYYYHNSGLQNQSVLMRAMSLTDTAPSIFLDPNSMSSDGTTALKATAWSEDESMLA\r\nYSLSDKGSDWQRIHVRRADTVEDTSDVIEWAKFTAIAWWHNLGFFYTRYPALQGDVDKGAETDAAQDAFI\r\nCFHRIGRPQDEDVVILSVPEHPQWNMGASVSDCHSYVIVVLFDGCEPHNLVWVAELPSVEKGLGSEPLVF\r\nKKLVNEFAGRYTYLGNEGSTFYFVTTRDAPRKKIVSIDIHTGQETVIVEQQRSVLSQAALVKKTLLLAYL\r\nEDVKDVFYYCRLEDPTLNAIPLPIGTITSFFSDRKKDFVSFKITSFLLPGRSFFLDINDPQSSLRVFKDD\r\nTVEGLLVDDFVTEQTFYNSSDGVRIPMFIVYRKGSVSSESPLLLYGYGGFNIPLTPAFSSSRMVFLRDLG\r\nGVLAVLNIRGGGEYGEEWHDAGRRACKQNCFTDFIEGAKFLHRQGYGSPQTTAIMGGSNGGLLVAAVANQ\r\nAPELFRCVVCRVGVLDMYKFHKFTIGHAWKSDYGDPEKEEDFRVLQQYSPLHNIKSGIKYPAILVVTGDH\r\nDDRVVPLHSLKYVATLQHMNPNEGGPFLARIEVAAGHGAGKPTSKILREAGDIYTFIAKNINASWKE",
          "organism": "Trypanosoma cruzi",
          "uniprot_code": "Q71MD6",
          "uniprot_range_first": null,
          "uniprot_range_last": null,
          "oligomerization": "monomer",
          "molecular_type": "protein",
          "uniprot_sequence": "MRSVYPLARRSMAAYTMHNMTVPEPYDYLEDPENPETKTFVNEQNAFFEEYFASEAELRK\nKIFESISNSQDYPRTSNPSYINGHYYYYHNSGLQNQSVLMRAMSLTDTAPSIFLDPNSMS\nSDGTTALKATAWSEDESMLAYSLSDKGSDWQRIHVRRADTVEDTSDVIEWAKFTAIAWWH\nNLGFFYTRYPALQGDVDKGAETDAAQDAFICFHRIGRPQDEDVVILSVPEHPQWNMGASV\nSDCHSYVIVVLFDGCEPHNLVWVAELPSVEKGLGSEPLVFKKLVNEFAGRYTYLGNEGST\nFYFVTTRDAPRKKIVSIDIHTGQETVIVEQQRSVLSQAALVKKTLLLAYLEDVKDVFYYC\nRLEDPTLNAIPLPIGTITSFFSDRKKDFVSFKITSFLLPGRSFFLDINDPQSSLRVFKDD\nTVEGLLVDDFVTEQTFYNSSDGVRIPMFIVYRKGSVSSESPLLLYGYGGFNIPLTPAFSS\nSRMVFLRDLGGVLAVLNIRGGGEYGEEWHDAGRRACKQNCFTDFIEGAKFLHRQGYGSPQ\nTTAIMGGSNGGLLVAAVANQAPELFRCVVCRVGVLDMYKFHKFTIGHAWKSDYGDPEKEE\nDFRVLQQYSPLHNIKSGIKYPAILVVTGDHDDRVVPLHSLKYVATLQHMNPNEGGPFLAR\nIEVAAGHGAGKPTSKILREAGDIYTFIAKNINASWKE",
          "mw": 78.335,
          "total_mw": 78.335,
          "number_molecules": 1,
          "complex_state": false,
          "deuteration": null,
          "molecule_source": "biological",
          "molecule_description": "80 kDa prolyl oligopeptidase"
        }
      ],
      "buffer": {
        "name": "20 mM HEPES, 150 mM NaCl",
        "concentration_unit": null,
        "comment": "Purification buffer",
        "additive": null,
        "concentration": null,
        "pka": null,
        "ph": 7.4,
        "deuteration": null
      },
      "purity_method": null,
      "name": "STATIC-SAXS of Trypanosoma cruzi Prolyl Oligopepetidase (TcPOP)",
      "ext_coefficient": null,
      "contrast": null,
      "specific_vol": null,
      "dry_vol": null,
      "absorbption": null,
      "deuteration": null,
      "mixture": null
    },
    "contributor": [
      {
        "affiliation": [
          {
            "short_name": null,
            "address": null,
            "full_name": "university of nottingham",
            "webpage": null
          }
        ],
        "contributor_name": "Ivan",
        "contributor_surname": "Campeotto",
        "orcid": "https://orcid.org/0000-0002-0814-619X"
      }
    ],
    "concentration_method": null,
    "concentration_unit": null,
    "date": "2023-04-24",
    "storage_temperature": 15.0,
    "cell_temperature": 15.0,
    "exposure_time": 1.0,
    "number_of_frames": 21,
    "wavelength": 0.09464,
    "sample_detector_distance": 3.6856,
    "concentration_min": 0.3,
    "concentration_max": 6.0,
    "sample_volume": 50.0,
    "flow_rate": 0.08,
    "s_min": 0.045,
    "s_max": 3.4,
    "total_exposure_time": null,
    "seccolumn": null
  },
  "fits": [],
  "estimated_volume_method": null,
  "pddf_software": "BioXTAS RAW",
  "pddf_software_version": null,
  "i0_calibration_standard": null,
  "description": "CAUTION! Data are severely over subtracted. CAUTION! Severe aggregation. CAUTION! The Rg, I(0), particle size/volume, molecular weight, p(r) and any other structural parameters derived from the data are undefined/uninterpretable.",
  "experiment_description": null,
  "tags": [],
  "intensity_unit": "arbitrary",
  "experimental_mw": 100.0,
  "experimental_mw_error": null,
  "guinier_i0_mw": 105.5,
  "guinier_i0_mw_error": null,
  "porod_mw": 106.0,
  "porod_mw_error": null,
  "pddf_i0": 0.01332995,
  "pddf_i0_error": null,
  "guinier_i0": 0.0417137,
  "guinier_i0_error": null,
  "pddf_rg": 0.0,
  "pddf_rg_error": null,
  "guinier_rg": 3.81,
  "guinier_rg_error": 0.615,
  "pddf_dmax": 0.03,
  "pddf_dmax_error": null,
  "porod_volume": 170.0,
  "porod_volume_error": null,
  "estimated_volume": null,
  "estimated_volume_error": null,
  "guinier_point_first": 155,
  "guinier_point_last": 232,
  "pddf_point_first": null,
  "pddf_point_last": null,
  "i0_calibration_standard_data": null,
  "intensities_log_log_plot": "SASDW33_datloglog_img.png",
  "symmetry": null,
  "last_modified": "2025-08-07T13:57:51.376271+02:00",
  "bragg_peak": []
}

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  "status": "success",
  "started_at": "2026-08-11T13:51:47.636294+00:00",
  "finished_at": "2026-08-11T13:51:59.691188+00:00",
  "source_last_modified": "2025-08-07T13:57:51.376271+02:00",
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