查看完整 summary.json 原文
{
"code": "SASDWN6",
"status": "Published",
"type_of_curve": "SEC-SAS",
"angular_unit": "1/A",
"project": {
"title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination",
"publication": {
"title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination",
"author_list": "Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A",
"journal": null,
"doi": "10.1101/2025.11.13.688182",
"pmid": null,
"published_date": "2025 Nov 13"
},
"status": "released",
"submitted_date": "2025-01-24",
"released_date": "2026-01-24"
},
"pddf_data": "https://www.sasbdb.org/media/p_of_R_files/SASDWN6.out",
"intensities_data": "https://www.sasbdb.org/media/intensities_files/SASDWN6.dat",
"intensities_log_plot": "https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDWN6_dat_img.png",
"intensities_kratky_plot": "https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDWN6_kratky_img.png",
"pddf_plot": "https://www.sasbdb.org/media/p_of_R_files/pofr_images/SASDWN6_pofr_img.png",
"intensities_guinier_plot": "https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDWN6_guinier_img.png",
"sascif_data": "https://www.sasbdb.org/media/sascif/sascif_files/SASDWN6.sascif",
"experiment": {
"instrument": {
"detector": {
"type": null,
"name": "Eiger 4M",
"resolution": 75.0
},
"name": "Diamond Light Source",
"city": "Didcot",
"country": "UK",
"beamline_name": "B21",
"beam_geometry": null,
"type_of_source": "X-ray synchrotron",
"point_source": null,
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"line_collimation_integrationwidth": null,
"xray_energy": null,
"beam_profile_ah": null,
"beam_profile_al": null
},
"sample": {
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{
"long_name": "Breast cancer type 2 susceptibility protein (BRC repeats 1-4)",
"short_name": "BRC1-4",
"sequence": "GNHSFGGSFRTASNKEIKLSEHNIKKSKMFFKDIEEQYPTSLACVEIVNTLALDNQKKLSKPQSINTVSAHLQSSVVVSDCKNSHITPQMLFSKQDFNSNHNLTPSQKAEITELSTILEESGSQFEFTQFRKPSYILQKSTFEVPENQMTILKTTSEECRDADLHVIMNAPSIGQVDSSKQFEGTVEIKRKFAGLLKNDCNKSASGYLTDENEVGFRGFYSAHGTKLNVSTEALQKAVKLFSDIENISEETSAEVHPISLSSSKCHDSVVSMFKIENHNDKTVSEKNNKCQLILQNNIEMTTGTFVEEITENYKRNTENEDNKYTAASRNSHNLEFDGSDSSKNDTVCIHKDETDLLFTDQHNICLKLSGQFMKEGNTQIKEDLSDLTFLEVAKAQEACHGNTSNKEQLTATKTEQNIKDFETSDTFFQTASGKNISVAKESFNKIVNFFDQKPEELHNFSLNSELHSDIRKNKMDILSYEETDIVKHKILKESVPVGTGNQLVTFQGQPERDEKIKEPTLLGFHTASGKKVKIAKESLDKVKNLFDEKEQ",
"organism": "Homo sapiens",
"uniprot_code": "P51587",
"uniprot_range_first": 1002,
"uniprot_range_last": 1551,
"oligomerization": "monomer",
"molecular_type": "protein",
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"mw": 62.058,
"total_mw": 62.058,
"number_molecules": 1,
"complex_state": false,
"deuteration": null,
"molecule_source": "biological",
"molecule_description": "BRCA2 Truncation containing BRC repeats 1, 2, 3 and 4"
},
{
"long_name": "DNA repair protein RAD51 homolog 1 (F86E A89E)",
"short_name": "RAD51 tetramer",
"sequence": "GMAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGETTETEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD",
"organism": "Homo sapiens",
"uniprot_code": "Q06609",
"uniprot_range_first": 1,
"uniprot_range_last": 339,
"oligomerization": "tetramer",
"molecular_type": "protein",
"uniprot_sequence": "MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKEL\nINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETG\nSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGL\nSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSA\nRQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRL\nYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD",
"mw": 37.063,
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"deuteration": null,
"molecule_source": "biological",
"molecule_description": "Human DNA repair protein RAD51 homolog 1 harbouring two substitutions in the oligomerization liker (F86E A89E) tetramer."
}
],
"buffer": {
"name": "20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 100 mM Li₂SO₄, 1 mM DTT, 1% sucrose",
"concentration_unit": null,
"comment": null,
"additive": null,
"concentration": null,
"pka": null,
"ph": 8.0,
"deuteration": null
},
"purity_method": null,
"name": "RAD51 [F86E, A89E] in complex with BRCA2 truncation containing the first, second, third and fourth BRC repeats (BRC1-4) SEC-SAXS",
"ext_coefficient": null,
"contrast": null,
"specific_vol": null,
"dry_vol": null,
"absorbption": null,
"deuteration": null,
"mixture": null
},
"contributor": [
{
"affiliation": [
{
"short_name": null,
"address": null,
"full_name": "istituto italiano di tecnologia",
"webpage": null
}
],
"contributor_name": "Francesco",
"contributor_surname": "Rinaldi",
"orcid": "https://orcid.org/0000-0001-7042-2071"
}
],
"concentration_method": null,
"concentration_unit": null,
"date": "2024-12-02",
"storage_temperature": 15.0,
"cell_temperature": 15.0,
"exposure_time": 3.0,
"number_of_frames": 600,
"wavelength": 0.09464,
"sample_detector_distance": 3.688,
"concentration_min": null,
"concentration_max": 3.7,
"sample_volume": 55.0,
"flow_rate": 0.07,
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"total_exposure_time": null,
"seccolumn": 59
},
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"description": "Molecular weight has been inferred through Volume of Correlation (Vc). Sample molecular weight and monodispersity has been independently confirmed through static light scattering (SLS). 16 successive frames were collected through the sample elution peak (from a total of 600 frames).",
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"tags": [],
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"last_modified": "2026-02-10T10:05:36.119700+01:00",
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}
