The following content comes directly from the SASBDB entry. Missing values are shown as “—”; SAXSdb does not infer undeclared units.
Every source field is expanded here, including empty values, list members and fields already shown above.
View the complete summary.json source
{
"code": "SASDWU2",
"status": "Published",
"type_of_curve": "SEC-SAS",
"angular_unit": "1/A",
"project": {
"title": "Structure-guided disulfide engineering restricts antibody conformation to elicit TNFR agonism.",
"publication": {
"title": "Structure-guided disulfide engineering restricts antibody conformation to elicit TNFR agonism.",
"author_list": "Elliott IG, Fisher H, Chan HTC, Inzhelevskaya T, Mockridge CI, Penfold CA, Duriez PJ, Orr CM, Herniman J, Müller KTJ, Essex JW, Cragg MS, Tews I",
"journal": "Nat Commun",
"doi": "10.1038/s41467-025-58773-8",
"pmid": "40221417",
"published_date": "2025 Apr 12"
},
"status": "released",
"submitted_date": "2023-07-12",
"released_date": "2025-02-25"
},
"pddf_data": "https://www.sasbdb.org/media/p_of_R_files/SASDWU2.out",
"intensities_data": "https://www.sasbdb.org/media/intensities_files/SASDWU2.dat",
"intensities_log_plot": "https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDWU2_dat_img.png",
"intensities_kratky_plot": "https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDWU2_kratky_img.png",
"pddf_plot": "https://www.sasbdb.org/media/p_of_R_files/pofr_images/SASDWU2_pofr_img.png",
"intensities_guinier_plot": "https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDWU2_guinier_img.png",
"sascif_data": "https://www.sasbdb.org/media/sascif/sascif_files/SASDWU2.sascif",
"experiment": {
"instrument": {
"detector": {
"type": null,
"name": "Pilatus3 2M",
"resolution": 0.172
},
"name": "ESRF",
"city": "Grenoble",
"country": "France",
"beamline_name": "BM29",
"beam_geometry": "point",
"type_of_source": "X-ray synchrotron",
"point_source": null,
"line_collimation": null,
"sample_path_length": null,
"line_collimation_slitlength": null,
"line_collimation_integrationwidth": null,
"xray_energy": null,
"beam_profile_ah": null,
"beam_profile_al": null
},
"sample": {
"molecule": [
{
"long_name": "Human immunoglobulin gamma 1 (IgG1) ChiLob 7/4 - kappa light chain",
"short_name": null,
"sequence": "DIQMTQTTSSLSASLGDRVTITCSASQGINNYLNWYQQKPDGTVKLLIYYTSSLHSGVPSRFSGSGSGTDYSLTISNLEPEDIATYYCQQYSNLPYTFGGGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC",
"organism": "Homo sapiens",
"uniprot_code": null,
"uniprot_range_first": null,
"uniprot_range_last": null,
"oligomerization": "dimer",
"molecular_type": "protein",
"uniprot_sequence": "",
"mw": 23.444,
"total_mw": 46.888,
"number_molecules": 2,
"complex_state": false,
"deuteration": null,
"molecule_source": "biological",
"molecule_description": ""
},
{
"long_name": "Human immunoglobulin gamma 2 (IgG2) ChiLob 7/4 - heavy chain C224S/C225S",
"short_name": null,
"sequence": "EVQLQQSGPDLVKPGASVKISCKTSGYTFTEYIMHWVKQSHGKSLEWIGGIIPNNGGTSYNQKFKDKATMTVDKSSSTGYMELRSLTSEDSAVYYCTRREVYGRNYYALDYWGQGTLVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSNFGTQTYTCNVDHKPSNTKVDKTVERKSSVECPPCPAPPVAGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTFRVVSVLTVVHQDWLNGKEYKCKVSNKGLPAPIEKTISKTKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPMLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK",
"organism": "Homo sapiens",
"uniprot_code": null,
"uniprot_range_first": null,
"uniprot_range_last": null,
"oligomerization": "dimer",
"molecular_type": "protein",
"uniprot_sequence": "",
"mw": 49.493,
"total_mw": 98.986,
"number_molecules": 2,
"complex_state": false,
"deuteration": null,
"molecule_source": "biological",
"molecule_description": ""
}
],
"buffer": {
"name": "50 mM HEPES, 150 mM KCl",
"concentration_unit": null,
"comment": null,
"additive": null,
"concentration": null,
"pka": null,
"ph": 7.5,
"deuteration": null
},
"purity_method": null,
"name": "Human immunoglobulin gamma 2 (IgG2) ChiLob 7/4 - heavy chain C224S/C225S mutant",
"ext_coefficient": null,
"contrast": null,
"specific_vol": null,
"dry_vol": null,
"absorbption": null,
"deuteration": null,
"mixture": null
},
"contributor": [
{
"affiliation": [
{
"short_name": null,
"address": "Southampton, UK",
"full_name": "University of Southampton",
"webpage": "https://www.southampton.ac.uk/"
}
],
"contributor_name": "Isabel",
"contributor_surname": "Elliott",
"orcid": "https://orcid.org/0000-0003-4535-5932"
}
],
"concentration_method": null,
"concentration_unit": null,
"date": "2024-11-29",
"storage_temperature": 4.0,
"cell_temperature": 20.0,
"exposure_time": 3.0,
"number_of_frames": 500,
"wavelength": 0.099,
"sample_detector_distance": 2.7,
"concentration_min": null,
"concentration_max": 12.6,
"sample_volume": 75.0,
"flow_rate": 0.25,
"s_min": 0.06,
"s_max": 4.959,
"total_exposure_time": null,
"seccolumn": 10
},
"fits": [],
"estimated_volume_method": null,
"pddf_software": "ATSAS GNOM",
"pddf_software_version": "4.0.1-1",
"i0_calibration_standard": null,
"description": null,
"experiment_description": null,
"tags": [],
"intensity_unit": "arbitrary",
"experimental_mw": 169.6,
"experimental_mw_error": null,
"guinier_i0_mw": null,
"guinier_i0_mw_error": null,
"porod_mw": 157.0,
"porod_mw_error": null,
"pddf_i0": 375.2,
"pddf_i0_error": 0.26,
"guinier_i0": 375.465,
"guinier_i0_error": null,
"pddf_rg": 5.06,
"pddf_rg_error": 0.004,
"guinier_rg": 5.035,
"guinier_rg_error": 0.061,
"pddf_dmax": 16.5,
"pddf_dmax_error": null,
"porod_volume": 215.0,
"porod_volume_error": null,
"estimated_volume": null,
"estimated_volume_error": null,
"guinier_point_first": 2,
"guinier_point_last": 40,
"pddf_point_first": null,
"pddf_point_last": null,
"i0_calibration_standard_data": null,
"intensities_log_log_plot": "SASDWU2_datloglog_img.png",
"symmetry": null,
"last_modified": "2026-03-06T17:19:40.880508+01:00",
"bragg_peak": []
}View the complete manifest.json source
{
"code": "SASDWU2",
"status": "success",
"started_at": "2026-08-11T13:46:52.099274+00:00",
"finished_at": "2026-08-11T13:47:00.978410+00:00",
"source_last_modified": "2026-03-06T17:19:40.880508+01:00",
"files": [
{
"status": "downloaded",
"url": "https://www.sasbdb.org/rest-api/entry/summary/SASDWU2/",
"path": "/data/saxsdb/sasbdb/entries/u2/sasdwu2/source/summary.json",
"size": 6673,
"sha256": "c09b91f978664c788c1750c768da5d7e3c5952a26052ab1692caad789bd9150a"
},
{
"status": "downloaded",
"url": "https://www.sasbdb.org/media/intensities_files/SASDWU2.dat",
"path": "/data/saxsdb/sasbdb/entries/u2/sasdwu2/source/SASDWU2.dat",
"size": 53243,
"sha256": "0b1a52901eebbd74f5a9d9c6d7651b1bc285fe7272076654fc51548c838e9c1c",
"role": "curve"
},
{
"status": "downloaded",
"url": "https://www.sasbdb.org/media/p_of_R_files/SASDWU2.out",
"path": "/data/saxsdb/sasbdb/entries/u2/sasdwu2/source/SASDWU2.out",
"size": 56202,
"sha256": "3fdcbdd35c03586cf2b835003b823987981e409fcd8ce987703ebdbb9ddb1730",
"role": "pddf"
},
{
"status": "not_available",
"url": "https://www.sasbdb.org/media/sascif/sascif_files/SASDWU2.sascif",
"path": "/data/saxsdb/sasbdb/entries/u2/sasdwu2/source/SASDWU2.sascif",
"role": "sascif"
},
{
"status": "downloaded",
"url": "https://www.sasbdb.org/media/zip_directories/SASDWU2.zip",
"path": "/data/saxsdb/sasbdb/entries/u2/sasdwu2/source/SASDWU2.zip",
"size": 33044,
"sha256": "b57a2659d0a97cca70b9ec13a9edfb47eff8e7109d12fff2445db4c20f56d186",
"role": "full_entry_zip",
"zip_member_count": 2,
"zip_validation": "central_directory_readable"
}
]
}
