SASDXJ6

CD2-associated protein (CD2AP)

数据类型:SASBDB 实验数据 状态:Published 曲线类型:Single concentration 最后更新:2026-05-19T09:37:42.000201+02:00

wild type cd2ap 6mg. First seven points removed for display purposes. Porod volume estimation for the molecule is inconclusive.

1. 样品、组分与实验条件 Sample & Experiment

样品 1 · CD2-associated protein (CD2AP)

浓度— – 6.0 缓冲液 / pH10 mM potassium phosphate / 7.6
Experimental temperature10.0 设备 / 束线CSIR-Central Drug Research Institute / Anton Paar SAXSpace
波长0.154 nm曝光900.0 s × 4

分子组分

组分类型 / OrganismUniProt 与Construct寡聚状态Molecular weight
CD2-associated protein
查看序列
MVDYIVEYDYDAVHDDELTIRVGEIIRNVKKLQEEGWLEGELNGRRGMFPDNFVKEIKRETEFKDDSLPIKRERHGNVASLVQRISTYGLPAGGIQPHPQTKNIKKKTKKRQCKVLFEYIPQNEDELELKVGDIIDINEEVEEGWWSGTLNNKLGLFPSNFVKELEVTDDGETHEAQDDSETVLAGPTSPIPSLGNVSETASGSVTQPKKIRGIGFGDIFKEGSVKLRTRTSSSETEEKKPEKPLILQSLGPKTQSVEITKTDTEGKIKAKEYCRTLFAYEGTNEDELTFKEGEIIHLISKETGEAGWWRGELNGKEGVFPDNFAVQINELDKDFPKPKKPPPPAKAPAPKPELIAAEKKYFSLKPEEKDEKSTLEQKPSKPAAPQVPPKKPTPPTKASNLLRSSGTVYPKRPEKPVPPPPPIAKINGEVSSISSKFETEPVSKLKLDSEQLPLRPKSVDFDSLTVRTSKETDVVNFDDIASSENLLHLTANRPKMPGRRLPGRFNGGHSPTHSPEKILKLPKEEDSANLKPSELKKDTCYSPKPSVYLSTPSSASKANTTAFLTPLEIKAKVETDDVKKNSLDELRAQIIELLCIVEALKKDHGKELEKLRKDLEEEKTMRSNLEMEIEKLKKAVLSS
proteinHomo sapiensQ9Y5K6—–—hexamer分子数 671.45 kDa

实验曲线

曲线点数 / 列q range误差质量负强度点来源文件
11208[3]0.07706908–7.7751 1/nm含误差列缺失 00sasbdb/entries/j6/sasdxj6/source/SASDXJ6.dat

2. SASBDB 报告的指标 Reported Results

指标方法数值误差单位
dmaxP(r)35.5nm
i0Guinier49033.3arbitrary
i0P(r)51960.0arbitrary
mwExperimental318.0kDa
mwGuinier I(0)480.3729.4kDa
rgGuinier10.6624.694nm
rgP(r)11.4nm

这些数值是 SASBDB 来源记录,不是 SAXSdb 对实验曲线重新计算的结果。

3. 来源拟合与模型 Source Fits & Models

该条目没有来源拟合记录。

4. 来源文件索引 Source Files

5. 实验说明与论文 Experiment & Publication

6. 完整来源记录 Complete Source Record

下列内容直接来自 SASBDB 条目。字段没有值时显示“—”;Not declared的单位不会由 SAXSdb 猜测。

打开 SASBDB 原始条目

缓冲液与样品属性

缓冲液名称10 mM potassium phosphate缓冲液浓度
pH7.6添加剂
缓冲液说明
纯度测定方法消光系数
吸收值散射对比度
比体积 / 干体积— / —混合物 / 氘代— / —

采集条件与仪器

测量日期2025-05-16储存 / 测量温度10.0 / 10.0
曝光时间900.0帧数4
波长0.154样品-探测器距离0.317
光源X-ray in house探测器Mythen2 R 1K
机构 / 束线CSIR-Central Drug Research Institute / Anton Paar SAXSpace · Lucknow, India
q range0.077 – 7.775样品体积 / 流速— / —

SASBDB 原始图

实验 I(q)
实验 I(q)
实验 I(q) log-log
实验 I(q) log-log
Guinier 图
Guinier 图
Kratky 图
Kratky 图

可Download文件

类别文件状态大小校验值Download与查看
curvesasbdb/entries/j6/sasdxj6/source/SASDXJ6.datdownloaded55633c5cb4dca4e2dd0bedeee756460fea6046d696b06c2996d8a8d8493a90bc11b82Download查看原文件源站
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pddfsasbdb/entries/j6/sasdxj6/source/SASDXJ6.outnot_listedDownload查看原文件
sascifsasbdb/entries/j6/sasdxj6/source/SASDXJ6.sascifnot_availableDownload查看原文件源站
summarysasbdb/entries/j6/sasdxj6/source/summary.jsondownloaded6282bbcdd96b7406aa176e721967905aca94b20fb39cfe07f8e0537c287f4f4a3368Download查看原文件源站
curve:来源记录
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  "status": "downloaded",
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}
full_entry_zip:来源记录与 ZIP 内部目录(1 项)
{
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  "role": "full_entry_zip",
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  "size": 17295,
  "status": "downloaded",
  "url": "https://www.sasbdb.org/media/zip_directories/SASDXJ6.zip",
  "zip_member_count": 1,
  "zip_members": [
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pddf:来源记录
{
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  "role": "pddf",
  "status": "not_listed"
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sascif:来源记录
{
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  "role": "sascif",
  "status": "not_available",
  "url": "https://www.sasbdb.org/media/sascif/sascif_files/SASDXJ6.sascif"
}
summary:来源记录
{
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  "size": 6282,
  "status": "downloaded",
  "url": "https://www.sasbdb.org/rest-api/entry/summary/SASDXJ6/"
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全部来源字段(无筛选)

这里自动展开来源记录中的每一个字段,包括空值、列表成员和页面上方已展示过的字段。

summary.json:129 个字段值
字段路径原始值
codeSASDXJ6
statusPublished
type_of_curveSingle concentration
angular_unit1/nm
project.titleCD2AP’s Structure and Oligomerization are compromised by the K301M mutation: implications for Nephrotic syndrome
project.publicationnull
project.statusreleased
project.submitted_date2025-07-16
project.released_date2026-05-09
pddf_datanull
intensities_datahttps://www.sasbdb.org/media/intensities_files/SASDXJ6.dat
intensities_log_plothttps://www.sasbdb.org/media/intensities_files/scattering_plots/SASDXJ6_dat_img.png
intensities_kratky_plothttps://www.sasbdb.org/media/intensities_files/scattering_plots/SASDXJ6_kratky_img.png
pddf_plotnull
intensities_guinier_plothttps://www.sasbdb.org/media/intensities_files/scattering_plots/SASDXJ6_guinier_img.png
sascif_datahttps://www.sasbdb.org/media/sascif/sascif_files/SASDXJ6.sascif
experiment.instrument.detector.typeHybrid Photon Counting (HPC)
experiment.instrument.detector.nameMythen2 R 1K
experiment.instrument.detector.resolutionnull
experiment.instrument.nameCSIR-Central Drug Research Institute
experiment.instrument.cityLucknow
experiment.instrument.countryIndia
experiment.instrument.beamline_nameAnton Paar SAXSpace
experiment.instrument.beam_geometrynull
experiment.instrument.type_of_sourceX-ray in house
experiment.instrument.point_sourcenull
experiment.instrument.line_collimationnull
experiment.instrument.sample_path_lengthnull
experiment.instrument.line_collimation_slitlengthnull
experiment.instrument.line_collimation_integrationwidthnull
experiment.instrument.xray_energynull
experiment.instrument.beam_profile_ahnull
experiment.instrument.beam_profile_alnull
experiment.sample.molecule[0].long_nameCD2-associated protein
experiment.sample.molecule[0].short_namenull
experiment.sample.molecule[0].sequenceMVDYIVEYDYDAVHDDELTIRVGEIIRNVKKLQEEGWLEGELNGRRGMFPDNFVKEIKRE TEFKDDSLPIKRERHGNVASLVQRISTYGLPAGGIQPHPQTKNIKKKTKKRQCKVLFEYI PQNEDELELKVGDIIDINEEVEEGWWSGTLNNKLGLFPSNFVKELEVTDDGETHEAQDDS ETVLAGPTSPIPSLGNVSETASGSVTQPKKIRGIGFGDIFKEGSVKLRTRTSSSETEEKK PEKPLILQSLGPKTQSVEITKTDTEGKIKAKEYCRTLFAYEGTNEDELTFKEGEIIHLIS KETGEAGWWRGELNGKEGVFPDNFAVQINELDKDFPKPKKPPPPAKAPAPKPELIAAEKK YFSLKPEEKDEKSTLEQKPSKPAAPQVPPKKPTPPTKASNLLRSSGTVYPKRPEKPVPPP PPIAKINGEVSSISSKFETEPVSKLKLDSEQLPLRPKSVDFDSLTVRTSKETDVVNFDDI ASSENLLHLTANRPKMPGRRLPGRFNGGHSPTHSPEKILKLPKEEDSANLKPSELKKDTC YSPKPSVYLSTPSSASKANTTAFLTPLEIKAKVETDDVKKNSLDELRAQIIELLCIVEAL KKDHGKELEKLRKDLEEEKTMRSNLEMEIEKLKKAVLSS
experiment.sample.molecule[0].organismHomo sapiens
experiment.sample.molecule[0].uniprot_codeQ9Y5K6
experiment.sample.molecule[0].uniprot_range_firstnull
experiment.sample.molecule[0].uniprot_range_lastnull
experiment.sample.molecule[0].oligomerizationhexamer
experiment.sample.molecule[0].molecular_typeprotein
experiment.sample.molecule[0].uniprot_sequenceMVDYIVEYDYDAVHDDELTIRVGEIIRNVKKLQEEGWLEGELNGRRGMFPDNFVKEIKRE TEFKDDSLPIKRERHGNVASLVQRISTYGLPAGGIQPHPQTKNIKKKTKKRQCKVLFEYI PQNEDELELKVGDIIDINEEVEEGWWSGTLNNKLGLFPSNFVKELEVTDDGETHEAQDDS ETVLAGPTSPIPSLGNVSETASGSVTQPKKIRGIGFGDIFKEGSVKLRTRTSSSETEEKK PEKPLILQSLGPKTQSVEITKTDTEGKIKAKEYCRTLFAYEGTNEDELTFKEGEIIHLIS KETGEAGWWRGELNGKEGVFPDNFAVQINELDKDFPKPKKPPPPAKAPAPKPELIAAEKK YFSLKPEEKDEKSTLEQKPSKPAAPQVPPKKPTPPTKASNLLRSSGTVYPKRPEKPVPPP PPIAKINGEVSSISSKFETEPVSKLKLDSEQLPLRPKSVDFDSLTVRTSKETDVVNFDDI ASSENLLHLTANRPKMPGRRLPGRFNGGHSPTHSPEKILKLPKEEDSANLKPSELKKDTC YSPKPSVYLSTPSSASKANTTAFLTPLEIKAKVETDDVKKNSLDELRAQIIELLCIVEAL KKDHGKELEKLRKDLEEEKTMRSNLEMEIEKLKKAVLSS
experiment.sample.molecule[0].mw71.45
experiment.sample.molecule[0].total_mw428.7
experiment.sample.molecule[0].number_molecules6
experiment.sample.molecule[0].complex_stateFalse
experiment.sample.molecule[0].deuterationnull
experiment.sample.molecule[0].molecule_sourcebiological
experiment.sample.molecule[0].molecule_descriptionThis is the WT CD2AP protein
experiment.sample.buffer.name10 mM potassium phosphate
experiment.sample.buffer.concentration_unitnull
experiment.sample.buffer.commentnull
experiment.sample.buffer.additivenull
experiment.sample.buffer.concentrationnull
experiment.sample.buffer.pkanull
experiment.sample.buffer.ph7.6
experiment.sample.buffer.deuterationnull
experiment.sample.purity_methodnull
experiment.sample.nameCD2-associated protein (CD2AP)
experiment.sample.ext_coefficientnull
experiment.sample.contrastnull
experiment.sample.specific_volnull
experiment.sample.dry_volnull
experiment.sample.absorbptionnull
experiment.sample.deuterationnull
experiment.sample.mixturenull
experiment.contributor[0].affiliation[0].short_namenull
experiment.contributor[0].affiliation[0].addressnull
experiment.contributor[0].affiliation[0].full_nameuniversity of Hyderabad India
experiment.contributor[0].affiliation[0].webpagenull
experiment.contributor[0].contributor_nameAnil Kumar
experiment.contributor[0].contributor_surnamePasupulati et .al
experiment.contributor[0].orcidhttps://orcid.org/0000-0001-9467-7650
experiment.concentration_methodnull
experiment.concentration_unitnull
experiment.date2025-05-16
experiment.storage_temperature10.0
experiment.cell_temperature10.0
experiment.exposure_time900.0
experiment.number_of_frames4
experiment.wavelength0.154
experiment.sample_detector_distance0.317
experiment.concentration_minnull
experiment.concentration_max6.0
experiment.sample_volumenull
experiment.flow_ratenull
experiment.s_min0.077
experiment.s_max7.775
experiment.total_exposure_timenull
experiment.seccolumnnull
fits[]
estimated_volume_methodnull
pddf_softwareATSAS GNOM
pddf_software_version5.0
i0_calibration_standardnull
descriptionwild type cd2ap 6mg. First seven points removed for display purposes. Porod volume estimation for the molecule is inconclusive.
experiment_descriptionnull
tags[]
intensity_unitarbitrary
experimental_mw318.0
experimental_mw_errornull
guinier_i0_mw480.37
guinier_i0_mw_error29.4
porod_mwnull
porod_mw_errornull
pddf_i051960.0
pddf_i0_errornull
guinier_i049033.3
guinier_i0_errornull
pddf_rg11.4
pddf_rg_errornull
guinier_rg10.662
guinier_rg_error4.694
pddf_dmax35.5
pddf_dmax_errornull
porod_volumenull
porod_volume_errornull
estimated_volumenull
estimated_volume_errornull
guinier_point_first7
guinier_point_last14
pddf_point_firstnull
pddf_point_lastnull
i0_calibration_standard_datanull
intensities_log_log_plotSASDXJ6_datloglog_img.png
symmetrynull
last_modified2026-05-19T09:37:42.000201+02:00
bragg_peak[]
manifest.json:31 个字段值
字段路径原始值
codeSASDXJ6
statussuccess
started_at2026-08-11T16:26:26.928408+00:00
finished_at2026-08-11T16:26:32.528514+00:00
source_last_modified2026-05-19T09:37:42.000201+02:00
files[0].statusdownloaded
files[0].urlhttps://www.sasbdb.org/rest-api/entry/summary/SASDXJ6/
files[0].path/data/saxsdb/sasbdb/entries/j6/sasdxj6/source/summary.json
files[0].size6282
files[0].sha256bbcdd96b7406aa176e721967905aca94b20fb39cfe07f8e0537c287f4f4a3368
files[1].statusdownloaded
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files[1].path/data/saxsdb/sasbdb/entries/j6/sasdxj6/source/SASDXJ6.dat
files[1].size55633
files[1].sha256c5cb4dca4e2dd0bedeee756460fea6046d696b06c2996d8a8d8493a90bc11b82
files[1].rolecurve
files[2].rolepddf
files[2].statusnot_listed
files[2].path/data/saxsdb/sasbdb/entries/j6/sasdxj6/source/SASDXJ6.out
files[3].statusnot_available
files[3].urlhttps://www.sasbdb.org/media/sascif/sascif_files/SASDXJ6.sascif
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files[3].rolesascif
files[4].statusdownloaded
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files[4].rolefull_entry_zip
files[4].zip_member_count1
files[4].zip_validationcentral_directory_readable
查看完整 summary.json 原文
{
  "code": "SASDXJ6",
  "status": "Published",
  "type_of_curve": "Single concentration",
  "angular_unit": "1/nm",
  "project": {
    "title": "CD2AP’s Structure and Oligomerization are compromised by the K301M mutation: implications for Nephrotic syndrome",
    "publication": null,
    "status": "released",
    "submitted_date": "2025-07-16",
    "released_date": "2026-05-09"
  },
  "pddf_data": null,
  "intensities_data": "https://www.sasbdb.org/media/intensities_files/SASDXJ6.dat",
  "intensities_log_plot": "https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDXJ6_dat_img.png",
  "intensities_kratky_plot": "https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDXJ6_kratky_img.png",
  "pddf_plot": null,
  "intensities_guinier_plot": "https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDXJ6_guinier_img.png",
  "sascif_data": "https://www.sasbdb.org/media/sascif/sascif_files/SASDXJ6.sascif",
  "experiment": {
    "instrument": {
      "detector": {
        "type": "Hybrid Photon Counting (HPC)",
        "name": "Mythen2 R 1K",
        "resolution": null
      },
      "name": "CSIR-Central Drug Research Institute",
      "city": "Lucknow",
      "country": "India",
      "beamline_name": "Anton Paar SAXSpace",
      "beam_geometry": null,
      "type_of_source": "X-ray in house",
      "point_source": null,
      "line_collimation": null,
      "sample_path_length": null,
      "line_collimation_slitlength": null,
      "line_collimation_integrationwidth": null,
      "xray_energy": null,
      "beam_profile_ah": null,
      "beam_profile_al": null
    },
    "sample": {
      "molecule": [
        {
          "long_name": "CD2-associated protein",
          "short_name": null,
          "sequence": "MVDYIVEYDYDAVHDDELTIRVGEIIRNVKKLQEEGWLEGELNGRRGMFPDNFVKEIKRE\r\nTEFKDDSLPIKRERHGNVASLVQRISTYGLPAGGIQPHPQTKNIKKKTKKRQCKVLFEYI\r\nPQNEDELELKVGDIIDINEEVEEGWWSGTLNNKLGLFPSNFVKELEVTDDGETHEAQDDS\r\nETVLAGPTSPIPSLGNVSETASGSVTQPKKIRGIGFGDIFKEGSVKLRTRTSSSETEEKK\r\nPEKPLILQSLGPKTQSVEITKTDTEGKIKAKEYCRTLFAYEGTNEDELTFKEGEIIHLIS\r\nKETGEAGWWRGELNGKEGVFPDNFAVQINELDKDFPKPKKPPPPAKAPAPKPELIAAEKK\r\nYFSLKPEEKDEKSTLEQKPSKPAAPQVPPKKPTPPTKASNLLRSSGTVYPKRPEKPVPPP\r\nPPIAKINGEVSSISSKFETEPVSKLKLDSEQLPLRPKSVDFDSLTVRTSKETDVVNFDDI\r\nASSENLLHLTANRPKMPGRRLPGRFNGGHSPTHSPEKILKLPKEEDSANLKPSELKKDTC\r\nYSPKPSVYLSTPSSASKANTTAFLTPLEIKAKVETDDVKKNSLDELRAQIIELLCIVEAL\r\nKKDHGKELEKLRKDLEEEKTMRSNLEMEIEKLKKAVLSS",
          "organism": "Homo sapiens",
          "uniprot_code": "Q9Y5K6",
          "uniprot_range_first": null,
          "uniprot_range_last": null,
          "oligomerization": "hexamer",
          "molecular_type": "protein",
          "uniprot_sequence": "MVDYIVEYDYDAVHDDELTIRVGEIIRNVKKLQEEGWLEGELNGRRGMFPDNFVKEIKRE\nTEFKDDSLPIKRERHGNVASLVQRISTYGLPAGGIQPHPQTKNIKKKTKKRQCKVLFEYI\nPQNEDELELKVGDIIDINEEVEEGWWSGTLNNKLGLFPSNFVKELEVTDDGETHEAQDDS\nETVLAGPTSPIPSLGNVSETASGSVTQPKKIRGIGFGDIFKEGSVKLRTRTSSSETEEKK\nPEKPLILQSLGPKTQSVEITKTDTEGKIKAKEYCRTLFAYEGTNEDELTFKEGEIIHLIS\nKETGEAGWWRGELNGKEGVFPDNFAVQINELDKDFPKPKKPPPPAKAPAPKPELIAAEKK\nYFSLKPEEKDEKSTLEQKPSKPAAPQVPPKKPTPPTKASNLLRSSGTVYPKRPEKPVPPP\nPPIAKINGEVSSISSKFETEPVSKLKLDSEQLPLRPKSVDFDSLTVRTSKETDVVNFDDI\nASSENLLHLTANRPKMPGRRLPGRFNGGHSPTHSPEKILKLPKEEDSANLKPSELKKDTC\nYSPKPSVYLSTPSSASKANTTAFLTPLEIKAKVETDDVKKNSLDELRAQIIELLCIVEAL\nKKDHGKELEKLRKDLEEEKTMRSNLEMEIEKLKKAVLSS",
          "mw": 71.45,
          "total_mw": 428.7,
          "number_molecules": 6,
          "complex_state": false,
          "deuteration": null,
          "molecule_source": "biological",
          "molecule_description": "This is the WT CD2AP protein"
        }
      ],
      "buffer": {
        "name": "10 mM potassium phosphate",
        "concentration_unit": null,
        "comment": null,
        "additive": null,
        "concentration": null,
        "pka": null,
        "ph": 7.6,
        "deuteration": null
      },
      "purity_method": null,
      "name": "CD2-associated protein (CD2AP)",
      "ext_coefficient": null,
      "contrast": null,
      "specific_vol": null,
      "dry_vol": null,
      "absorbption": null,
      "deuteration": null,
      "mixture": null
    },
    "contributor": [
      {
        "affiliation": [
          {
            "short_name": null,
            "address": null,
            "full_name": "university of Hyderabad India ",
            "webpage": null
          }
        ],
        "contributor_name": "Anil Kumar",
        "contributor_surname": "Pasupulati et .al",
        "orcid": "https://orcid.org/0000-0001-9467-7650"
      }
    ],
    "concentration_method": null,
    "concentration_unit": null,
    "date": "2025-05-16",
    "storage_temperature": 10.0,
    "cell_temperature": 10.0,
    "exposure_time": 900.0,
    "number_of_frames": 4,
    "wavelength": 0.154,
    "sample_detector_distance": 0.317,
    "concentration_min": null,
    "concentration_max": 6.0,
    "sample_volume": null,
    "flow_rate": null,
    "s_min": 0.077,
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  "intensities_log_log_plot": "SASDXJ6_datloglog_img.png",
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  "last_modified": "2026-05-19T09:37:42.000201+02:00",
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}
查看完整 manifest.json 原文
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