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SASDYW5

La-related protein 6 (LARP6) La-module apo

数据类型：SASBDB 实验数据 状态：Published 曲线类型：Merged 最后更新：2026-02-21T16:07:18.021328+01:00

LARP6 La-module, residues 70-300, including the two structured La-motif and RNA-recognition motif 1. Experimental molecular weight was estimated by SEC-MALLS.

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1. 样品、组分与实验条件 Sample & Experiment

样品 1 · La-related protein 6 (LARP6) La-module apo

浓度4.0 – 5.0 缓冲液 / pH25 mM Tris-HCl, 100 mM KCl, 5 mM MgCl2, 1 mM DTT / 7.5
Experimental temperature15.0 设备 / 束线Diamond Light Source / B21
波长0.09537 nm曝光0.35 s × 600

分子组分

组分类型 / OrganismUniProt 与Construct寡聚状态Molecular weight
La-related protein 6
查看序列
GTTASGGENEREDLEQEWKPPDEELIKKLVDQIEFYFSDENLEKDAFLLKHVRRNKLGYVSVKLLTSFKKVKHLTRDWRTTAHALKYSVVLELNEDHRKVRRTTPVPLFPNENLPSKMLLVYDLYLSPKLWALATPQKNGRVQEKVMEHLLKLFGTFGVISSVRILKPGRELPPDIRRISSRYSQVGTQECAIVEFEEVEAAIKAHEFMITESQGKENMKAVLIGMKPPKKKP
proteinHomo sapiensQ9BRS870–300monomer分子数 126.883 kDa

实验曲线

曲线点数 / 列q range误差质量负强度点来源文件
12284[3]0.0081524106–0.30595432 1/A含误差列缺失 0150sasbdb/entries/w5/sasdyw5/source/SASDYW5.dat
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2. SASBDB 报告的指标 Reported Results

指标方法数值误差单位
dmaxP(r)8.25—Å
i0Guinier0.013843—arbitrary
i0P(r)0.1317473—arbitrary
mwExperimental36.4—kDa
mwPorod36.0—kDa
porod_volumePorod59.0—ų
rgGuinier2.8640.037Å
rgP(r)2.83—Å

这些数值是 SASBDB 来源记录，不是 SAXSdb 对实验曲线重新计算的结果。

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3. 来源拟合与模型 Source Fits & Models

该条目没有来源拟合记录。

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4. 来源文件索引 Source Files

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5. 实验说明与论文 Experiment & Publication

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6. 完整来源记录 Complete Source Record

下列内容直接来自 SASBDB 条目。字段没有值时显示“—”；Not declared的单位不会由 SAXSdb 猜测。

打开 SASBDB 原始条目

缓冲液与样品属性

缓冲液名称25 mM Tris-HCl, 100 mM KCl, 5 mM MgCl2, 1 mM DTT缓冲液浓度—
pH7.5添加剂—
缓冲液说明SEC-SAXS buffer
纯度测定方法—消光系数—
吸收值—散射对比度—
比体积 / 干体积— / —混合物 / 氘代— / —

采集条件与仪器

测量日期2024-10-01储存 / 测量温度4.0 / 15.0
曝光时间0.35帧数600
波长0.09537样品-探测器距离3.6903
光源X-ray synchrotron探测器Eiger 4M
机构 / 束线Diamond Light Source / B21 · Didcot, UK
q range0.082 – 3.06样品体积 / 流速— / —

SASBDB 原始图

实验 I(q)
实验 I(q)
实验 I(q) log-log
实验 I(q) log-log
Guinier 图
Guinier 图
Kratky 图
Kratky 图
P(r) 图
P(r) 图

可Download文件

类别文件状态大小校验值Download与查看
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sascifsasbdb/entries/w5/sasdyw5/source/SASDYW5.sascifnot_available——Download查看原文件源站
summarysasbdb/entries/w5/sasdyw5/source/summary.jsondownloaded6252f35cd51f0898c07ab321bdbff4fddbb7711292dd6051ed3ae695e896f3fcafc9Download查看原文件源站
curve：来源记录
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full_entry_zip：来源记录与 ZIP 内部目录（2 项）
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pddf：来源记录
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sascif：来源记录
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summary：来源记录
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全部来源字段（无筛选）

这里自动展开来源记录中的每一个字段，包括空值、列表成员和页面上方已展示过的字段。

summary.json：134 个字段值
字段路径原始值
codeSASDYW5
statusPublished
type_of_curveMerged
angular_unit1/A
project.titleAn intrinsically disordered region mediates RNA-binding selectivity and cellular activities of LARP6.
project.publication.titleAn intrinsically disordered region mediates RNA-binding selectivity and cellular activities of LARP6.
project.publication.author_listCapraro F, Abis G, Incocciati A, Simpson PJ, Karimzadeh M, Masino L, Barley A, Bui TTT, Kelly G, Goodarzi H, Conte MR, Mardakheh FK
project.publication.journalNat Commun
project.publication.doi10.1038/s41467-026-69789-z
project.publication.pmid41714637
project.publication.published_date2026 Feb 19
project.statusreleased
project.submitted_date2026-01-20
project.released_date2026-02-21
pddf_datahttps://www.sasbdb.org/media/p_of_R_files/SASDYW5.dat
intensities_datahttps://www.sasbdb.org/media/intensities_files/SASDYW5.txt
intensities_log_plothttps://www.sasbdb.org/media/intensities_files/scattering_plots/SASDYW5_dat_img.png
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pddf_plothttps://www.sasbdb.org/media/p_of_R_files/pofr_images/SASDYW5_pofr_img.png
intensities_guinier_plothttps://www.sasbdb.org/media/intensities_files/scattering_plots/SASDYW5_guinier_img.png
sascif_datahttps://www.sasbdb.org/media/sascif/sascif_files/SASDYW5.sascif
experiment.instrument.detector.typenull
experiment.instrument.detector.nameEiger 4M
experiment.instrument.detector.resolution75.0
experiment.instrument.nameDiamond Light Source
experiment.instrument.cityDidcot
experiment.instrument.countryUK
experiment.instrument.beamline_nameB21
experiment.instrument.beam_geometrynull
experiment.instrument.type_of_sourceX-ray synchrotron
experiment.instrument.point_sourcenull
experiment.instrument.line_collimationnull
experiment.instrument.sample_path_lengthnull
experiment.instrument.line_collimation_slitlengthnull
experiment.instrument.line_collimation_integrationwidthnull
experiment.instrument.xray_energynull
experiment.instrument.beam_profile_ahnull
experiment.instrument.beam_profile_alnull
experiment.sample.molecule[0].long_nameLa-related protein 6
experiment.sample.molecule[0].short_nameLARP6
experiment.sample.molecule[0].sequenceGTTASGGENEREDLEQEWKPPDEELIKKLVDQIEFYFSDENLEKDAFLLKHVRRNKLGYVSVKLLTSFKKVKHLTRDWRTTAHALKYSVVLELNEDHRKVRRTTPVPLFPNENLPSKMLLVYDLYLSPKLWALATPQKNGRVQEKVMEHLLKLFGTFGVISSVRILKPGRELPPDIRRISSRYSQVGTQECAIVEFEEVEAAIKAHEFMITESQGKENMKAVLIGMKPPKKKP
experiment.sample.molecule[0].organismHomo sapiens
experiment.sample.molecule[0].uniprot_codeQ9BRS8
experiment.sample.molecule[0].uniprot_range_first70
experiment.sample.molecule[0].uniprot_range_last300
experiment.sample.molecule[0].oligomerizationmonomer
experiment.sample.molecule[0].molecular_typeprotein
experiment.sample.molecule[0].uniprot_sequenceMAQSGGEARPGPKTAVQIRVAIQEAEDVDELEDEEEGAETRGAGDPARYLSPGWGSASEE EPSRGHSGTTASGGENEREDLEQEWKPPDEELIKKLVDQIEFYFSDENLEKDAFLLKHVR RNKLGYVSVKLLTSFKKVKHLTRDWRTTAHALKYSVVLELNEDHRKVRRTTPVPLFPNEN LPSKMLLVYDLYLSPKLWALATPQKNGRVQEKVMEHLLKLFGTFGVISSVRILKPGRELP PDIRRISSRYSQVGTQECAIVEFEEVEAAIKAHEFMITESQGKENMKAVLIGMKPPKKKP AKDKNHDEEPTASIHLNKSLNKRVEELQYMGDESSANSSSDPESNPTSPMAGRRHAATNK LSPSGHQNLFLSPNASPCTSPWSSPLAQRKGVSRKSPLAEEGRLNCSTSPEIFRKCMDYS SDSSVTPSGSPWVRRRRQAEMGTQEKSPGTSPLLSRKMQTADGLPVGVLRLPRGPDNTRG FHGHERSRACV
experiment.sample.molecule[0].mw26.883
experiment.sample.molecule[0].total_mw26.883
experiment.sample.molecule[0].number_molecules1
experiment.sample.molecule[0].complex_stateFalse
experiment.sample.molecule[0].deuterationnull
experiment.sample.molecule[0].molecule_sourcebiological
experiment.sample.molecule[0].molecule_descriptionLARP6 La-module, residues 70-300, including the two structured La-motif and RNA-recognition motif 1
experiment.sample.buffer.name25 mM Tris-HCl, 100 mM KCl, 5 mM MgCl2, 1 mM DTT
experiment.sample.buffer.concentration_unitnull
experiment.sample.buffer.commentSEC-SAXS buffer
experiment.sample.buffer.additivenull
experiment.sample.buffer.concentrationnull
experiment.sample.buffer.pkanull
experiment.sample.buffer.ph7.5
experiment.sample.buffer.deuterationnull
experiment.sample.purity_methodnull
experiment.sample.nameLa-related protein 6 (LARP6) La-module apo
experiment.sample.ext_coefficientnull
experiment.sample.contrastnull
experiment.sample.specific_volnull
experiment.sample.dry_volnull
experiment.sample.absorbptionnull
experiment.sample.deuterationnull
experiment.sample.mixturenull
experiment.contributor[0].affiliation[0].short_namenull
experiment.contributor[0].affiliation[0].addressLondon, UK
experiment.contributor[0].affiliation[0].full_nameKing's College London
experiment.contributor[0].affiliation[0].webpagehttps://www.kcl.ac.uk
experiment.contributor[0].contributor_nameGiancarlo
experiment.contributor[0].contributor_surnameAbis
experiment.contributor[0].orcid
experiment.concentration_methodnull
experiment.concentration_unitnull
experiment.date2024-10-01
experiment.storage_temperature4.0
experiment.cell_temperature15.0
experiment.exposure_time0.35
experiment.number_of_frames600
experiment.wavelength0.09537
experiment.sample_detector_distance3.6903
experiment.concentration_min4.0
experiment.concentration_max5.0
experiment.sample_volumenull
experiment.flow_ratenull
experiment.s_min0.082
experiment.s_max3.06
experiment.total_exposure_timenull
experiment.seccolumnnull
fits[]
estimated_volume_methodnull
pddf_softwareScÅtter
pddf_software_version4
i0_calibration_standardnull
descriptionLARP6 La-module, residues 70-300, including the two structured La-motif and RNA-recognition motif 1. Experimental molecular weight was estimated by SEC-MALLS.
experiment_descriptionnull
tags[]
intensity_unitarbitrary
experimental_mw36.4
experimental_mw_errornull
guinier_i0_mwnull
guinier_i0_mw_errornull
porod_mw36.0
porod_mw_errornull
pddf_i00.1317473
pddf_i0_errornull
guinier_i00.013843
guinier_i0_errornull
pddf_rg2.83
pddf_rg_errornull
guinier_rg2.864
guinier_rg_error0.037
pddf_dmax8.25
pddf_dmax_errornull
porod_volume59.0
porod_volume_errornull
estimated_volumenull
estimated_volume_errornull
guinier_point_first12
guinier_point_last376
pddf_point_firstnull
pddf_point_lastnull
i0_calibration_standard_datanull
intensities_log_log_plotSASDYW5_datloglog_img.png
symmetrynull
last_modified2026-02-21T16:07:18.021328+01:00
bragg_peak[]
manifest.json：34 个字段值
字段路径原始值
codeSASDYW5
statussuccess
started_at2026-08-11T14:58:13.563733+00:00
finished_at2026-08-11T14:58:20.752213+00:00
source_last_modified2026-02-21T16:07:18.021328+01:00
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查看完整 summary.json 原文
{
  "code": "SASDYW5",
  "status": "Published",
  "type_of_curve": "Merged",
  "angular_unit": "1/A",
  "project": {
    "title": "An intrinsically disordered region mediates RNA-binding selectivity and cellular activities of LARP6.",
    "publication": {
      "title": "An intrinsically disordered region mediates RNA-binding selectivity and cellular activities of LARP6.",
      "author_list": "Capraro F, Abis G, Incocciati A, Simpson PJ, Karimzadeh M, Masino L, Barley A, Bui TTT, Kelly G, Goodarzi H, Conte MR, Mardakheh FK",
      "journal": "Nat Commun",
      "doi": "10.1038/s41467-026-69789-z",
      "pmid": "41714637",
      "published_date": "2026 Feb 19"
    },
    "status": "released",
    "submitted_date": "2026-01-20",
    "released_date": "2026-02-21"
  },
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      "xray_energy": null,
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    },
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          "short_name": "LARP6",
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      },
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      "ext_coefficient": null,
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}
查看完整 manifest.json 原文
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