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1ad5

SRC FAMILY KINASE HCK-AMP-PNP COMPLEX

Method: X-RAY DIFFRACTION D_max: 109.5 Å Quality: GOOD

SAXS Profile

P(r) Distribution

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1. Structure Basics

entry_id	1ad5
deposition_date	1997-02-20
title	SRC FAMILY KINASE HCK-AMP-PNP COMPLEX
keywords	TYROSINE-PROTEIN KINASE, TRANSFERASE, SIGNAL TRANSDUCTION, SH2, SH3, PHOSPHORYLATION; TYROSINE-PROTEIN KINASE
method	X-RAY DIFFRACTION

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	32.30 Å
rg_electron	31.88 Å
i0	156863000.00
molecular_weight	100190.0 kDa
excluded_volume	125570 Å³
envelope_volume	163860 Å³
shell_volume	42853 Å³
envelope_diameter	114.0 Å
shell_rg	38.59 Å
envelope_rg	31.78 Å
shape_rg	31.89 Å
total_rg	32.42 Å
total_atoms	8572
n_residues	874
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	109.5 Å
rg_real	32.28 Å
rg_real_error	0.78 Å
i0_real	1.5690e+08
i0_real_error	2.4530e+06
rg_reciprocal	32.29 Å
i0_reciprocal	156900000.0000
total_estimate	0.8791
solution_quality	GOOD a GOOD solution
n_peaks	2
r_peak_primary	40.2 Å
skewness	0.353
kurtosis	-0.250
angular_range	— – 0.2450 Å⁻¹
current_alpha	0.0000
highest_alpha	35440000.0000
n_real_points	50
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.826; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.995; Smooth: 0.953

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4. Crystallography & Experiment

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5. Entities & Polymer Info (3)

Entity 1 polymer

description	HAEMATOPOETIC CELL KINASE HCK
formula_weight	50304.3 kDa
ec_number	2.7.1.112
src_method	man
entity_count	2

Polymer

type	polypeptide(L)
strand_id	A,B
atom_count	8572

EDIIVVALYDYEAIHHEDLSFQKGDQMVVLEESGEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSSKPQKPWEKDAWEIPRESLKLEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVEAFLAEANVMKTLQHDKLVKLHAVVTKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARVGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQYQQQP

Source

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Spodoptera frugiperda

Entity 2 non-polymer

description	CALCIUM ION
formula_weight	40.1 kDa
src_method	syn
entity_count	4

Entity 3 non-polymer

description	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
formula_weight	506.2 kDa
src_method	syn
entity_count	2

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6. Citations (1)

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length_a	72.767 Å
length_b	92.360 Å
length_c	178.290 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	8

space_group	P 21 21 21
int_tables_number	19
crystal_system	—

resolution	2.600 Å
resolution_low	18.000 Å
r_factor	0.2390
r_work	0.2390
r_free	0.3070

fit	/app/data/saxs_computation/ad/1ad5/1ad5.fit
pddf	/app/data/pr_computation/ad/1ad5/1ad5.pr.out
profile	/app/data/saxs_computation/ad/1ad5/1ad5.dat

SRC FAMILY KINASE HCK-AMP-PNP COMPLEX

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

Refinement

Diffraction