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1au1

HUMAN INTERFERON-BETA CRYSTAL STRUCTURE

Method: X-RAY DIFFRACTION D_max: 93.6 Å Quality: GOOD

SAXS Profile

P(r) Distribution

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1. Structure Basics

entry_id	1au1
deposition_date	1997-09-09
title	HUMAN INTERFERON-BETA CRYSTAL STRUCTURE
keywords	INTERFERON, HELICAL CYTOKINE, IMMUNE SYSTEM, CYTOKINE; INTERFERON
method	X-RAY DIFFRACTION

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	25.98 Å
rg_electron	25.22 Å
i0	27773900.00
molecular_weight	41160.0 kDa
excluded_volume	51837 Å³
envelope_volume	64486 Å³
shell_volume	22226 Å³
envelope_diameter	96.2 Å
shell_rg	30.93 Å
envelope_rg	25.66 Å
shape_rg	25.18 Å
total_rg	26.07 Å
total_atoms	3623
n_residues	329
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	93.6 Å
rg_real	26.12 Å
rg_real_error	0.84 Å
i0_real	2.7770e+07
i0_real_error	3.8900e+05
rg_reciprocal	26.08 Å
i0_reciprocal	27770000.0000
total_estimate	0.8309
solution_quality	GOOD a GOOD solution
n_peaks	2
r_peak_primary	24.5 Å
skewness	0.465
kurtosis	-0.235
angular_range	— – 0.3050 Å⁻¹
current_alpha	0.0000
highest_alpha	9525000.0000
n_real_points	62
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.712; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.728; Smooth: 0.932

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4. Crystallography & Experiment

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5. Entities & Polymer Info (5)

Entity 1 polymer

description	INTERFERON-BETA
formula_weight	20054.1 kDa
src_method	man
entity_count	2

Polymer

type	polypeptide(L)
strand_id	A,B
atom_count	3866

MSYNLLGFLQRSSNFQCQKLLWQLNGRLEYCLKDRMNFDIPEEIKQLQQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQINHLKTVLEEKLEKEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYFINRLTGYLRN

Source

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Cricetulus griseus

Entity 2 branched

description	;beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-[alpha-D-quinovopyranose-(1-6)]beta-D-glucopyranose ;
formula_weight	1137.0 kDa
src_method	man
entity_count	1

Entity 3 branched

description	alpha-D-quinovopyranose-(1-6)-beta-D-glucopyranose
formula_weight	326.3 kDa
src_method	man
entity_count	1

Entity 4 non-polymer

description	ZINC ION
formula_weight	65.4 kDa
src_method	syn
entity_count	1

Entity 5 water

description	water
formula_weight	18.0 kDa
src_method	nat
entity_count	81

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6. Citations (1)

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length_a	55.300 Å
length_b	65.900 Å
length_c	121.500 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	8

space_group	P 21 21 21
int_tables_number	19
crystal_system	—

resolution	2.200 Å
resolution_low	30.000 Å
r_factor	0.2230
r_work	0.2230
r_free	0.2830

fit	/app/data/saxs_computation/au/1au1/1au1.fit
pddf	/app/data/pr_computation/au/1au1/1au1.pr.out
profile	/app/data/saxs_computation/au/1au1/1au1.dat