SAXSdb — 1bbt

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1. Protein Identity and Related Structures Protein Identity & Related Structures

FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP1)

Foot-and-mouth disease virus

State in the Current Structure

Assembly	Oligomeric State	Construct	Mutations and Modifications	Ligands, Ions and Associated Components	Method and Experimental Conditions	Structure Quality
1	Protein heterocomplex Heteromer Protein × 240 PDB declaration: complete icosahedral assembly（240） Consistent with protein copy count	Chain 1； UniProt 508–720 Chain 2； UniProt 70–287 Chain 3； UniProt 288–507	Not recorded	FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP4) × 60 （O90754）	X-RAY DIFFRACTION mmCIF provides none of the parsed experimental conditions	Resolution 2.60 Å
2	Protein heterocomplex Heteromer Protein × 4 PDB declaration: tetrameric（4） Consistent with protein copy count	Chain 1； UniProt 508–720 Chain 2； UniProt 70–287 Chain 3； UniProt 288–507	Not recorded	FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP4) × 1 （O90754）	X-RAY DIFFRACTION mmCIF provides none of the parsed experimental conditions	Resolution 2.60 Å
3	Protein heterocomplex Heteromer Protein × 20 PDB declaration: eicosameric（20） Consistent with protein copy count	Chain 1； UniProt 508–720 Chain 2； UniProt 70–287 Chain 3； UniProt 288–507	Not recorded	FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP4) × 5 （O90754）	X-RAY DIFFRACTION mmCIF provides none of the parsed experimental conditions	Resolution 2.60 Å
4	Protein heterocomplex Heteromer Protein × 24 PDB declaration: 24-meric（24） Consistent with protein copy count	Chain 1； UniProt 508–720 Chain 2； UniProt 70–287 Chain 3； UniProt 288–507	Not recorded	FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP4) × 6 （O90754）	X-RAY DIFFRACTION mmCIF provides none of the parsed experimental conditions	Resolution 2.60 Å
5	Protein heterocomplex Heteromer Protein × 4 PDB declaration: tetrameric（4） Consistent with protein copy count	Chain 1； UniProt 508–720 Chain 2； UniProt 70–287 Chain 3； UniProt 288–507	Not recorded	FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP4) × 1 （O90754）	X-RAY DIFFRACTION mmCIF provides none of the parsed experimental conditions	Resolution 2.60 Å
6	Protein heterocomplex Heteromer Protein × 20 PDB declaration: eicosameric（20） Consistent with protein copy count	Chain 1； UniProt 508–720 Chain 2； UniProt 70–287 Chain 3； UniProt 288–507	Not recorded	FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP4) × 5 （O90754）	X-RAY DIFFRACTION mmCIF provides none of the parsed experimental conditions	Resolution 2.60 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB	Difference from Current Entry 1BBT	Assembly / Oligomeric State	Construct	Mutations and Modifications	Ligands, Ions and Non-polymers	Method and Experimental Conditions	Structure Quality
1FOD STRUCTURE OF A MAJOR IMMUNOGENIC SITE ON FOOT-AND-MOUTH DISEASE VIRUS Deposited 1993-10-27	Parsed fields agree	Assembly 1 Protein heterocomplex Heteromer；Protein × 240 PDB declaration: complete icosahedral assembly	Chain 1 508–720（213 aa） Chain 2 70–287（218 aa） Chain 3 288–507（220 aa）	Not recorded	No recorded non-water small molecule	X-RAY DIFFRACTION mmCIF provides none of the parsed conditions	Resolution 2.60 Å
1FOD STRUCTURE OF A MAJOR IMMUNOGENIC SITE ON FOOT-AND-MOUTH DISEASE VIRUS Deposited 1993-10-27	Parsed fields agree	Assembly 2 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric	Chain 1 508–720（213 aa） Chain 2 70–287（218 aa） Chain 3 288–507（220 aa）	Not recorded	No recorded non-water small molecule	X-RAY DIFFRACTION mmCIF provides none of the parsed conditions	Resolution 2.60 Å
1FOD STRUCTURE OF A MAJOR IMMUNOGENIC SITE ON FOOT-AND-MOUTH DISEASE VIRUS Deposited 1993-10-27	Parsed fields agree	Assembly 3 Protein heterocomplex Heteromer；Protein × 20 PDB declaration: eicosameric	Chain 1 508–720（213 aa） Chain 2 70–287（218 aa） Chain 3 288–507（220 aa）	Not recorded	No recorded non-water small molecule	X-RAY DIFFRACTION mmCIF provides none of the parsed conditions	Resolution 2.60 Å
1FOD STRUCTURE OF A MAJOR IMMUNOGENIC SITE ON FOOT-AND-MOUTH DISEASE VIRUS Deposited 1993-10-27	Parsed fields agree	Assembly 4 Protein heterocomplex Heteromer；Protein × 24 PDB declaration: 24-meric	Chain 1 508–720（213 aa） Chain 2 70–287（218 aa） Chain 3 288–507（220 aa）	Not recorded	No recorded non-water small molecule	X-RAY DIFFRACTION mmCIF provides none of the parsed conditions	Resolution 2.60 Å
1FOD STRUCTURE OF A MAJOR IMMUNOGENIC SITE ON FOOT-AND-MOUTH DISEASE VIRUS Deposited 1993-10-27	Parsed fields agree	Assembly 5 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric	Chain 1 508–720（213 aa） Chain 2 70–287（218 aa） Chain 3 288–507（220 aa）	Not recorded	No recorded non-water small molecule	X-RAY DIFFRACTION mmCIF provides none of the parsed conditions	Resolution 2.60 Å
1FOD STRUCTURE OF A MAJOR IMMUNOGENIC SITE ON FOOT-AND-MOUTH DISEASE VIRUS Deposited 1993-10-27	Parsed fields agree	Assembly 6 Protein heterocomplex Heteromer；Protein × 20 PDB declaration: eicosameric	Chain 1 508–720（213 aa） Chain 2 70–287（218 aa） Chain 3 288–507（220 aa）	Not recorded	No recorded non-water small molecule	X-RAY DIFFRACTION mmCIF provides none of the parsed conditions	Resolution 2.60 Å

1 other PDB entries and 6 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence

UniProt name	Q84771_9PICO
Isoform	—
PDB entities	1, 2, 3
Chains and sequence ranges	Author chain 1； PDBConstruct 1–213； UniProt 508–720 Author chain 2； PDBConstruct 1–218； UniProt 70–287 Author chain 3； PDBConstruct 1–220； UniProt 288–507

FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP4)

Foot-and-mouth disease virus

UniProt O90754

State in the Current Structure

Assembly	Oligomeric State	Construct	Mutations and Modifications	Ligands, Ions and Associated Components	Method and Experimental Conditions	Structure Quality
1	Protein heterocomplex Heteromer Protein × 240 PDB declaration: complete icosahedral assembly（240） Consistent with protein copy count	Chain 4； UniProt 1–85	Not recorded	FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP1) × 60 （Q84771） FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP2) × 60 （Q84771） FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP3) × 60 （Q84771）	X-RAY DIFFRACTION mmCIF provides none of the parsed experimental conditions	Resolution 2.60 Å
2	Protein heterocomplex Heteromer Protein × 4 PDB declaration: tetrameric（4） Consistent with protein copy count	Chain 4； UniProt 1–85	Not recorded	FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP1) × 1 （Q84771） FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP2) × 1 （Q84771） FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP3) × 1 （Q84771）	X-RAY DIFFRACTION mmCIF provides none of the parsed experimental conditions	Resolution 2.60 Å
3	Protein heterocomplex Heteromer Protein × 20 PDB declaration: eicosameric（20） Consistent with protein copy count	Chain 4； UniProt 1–85	Not recorded	FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP1) × 5 （Q84771） FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP2) × 5 （Q84771） FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP3) × 5 （Q84771）	X-RAY DIFFRACTION mmCIF provides none of the parsed experimental conditions	Resolution 2.60 Å
4	Protein heterocomplex Heteromer Protein × 24 PDB declaration: 24-meric（24） Consistent with protein copy count	Chain 4； UniProt 1–85	Not recorded	FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP1) × 6 （Q84771） FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP2) × 6 （Q84771） FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP3) × 6 （Q84771）	X-RAY DIFFRACTION mmCIF provides none of the parsed experimental conditions	Resolution 2.60 Å
5	Protein heterocomplex Heteromer Protein × 4 PDB declaration: tetrameric（4） Consistent with protein copy count	Chain 4； UniProt 1–85	Not recorded	FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP1) × 1 （Q84771） FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP2) × 1 （Q84771） FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP3) × 1 （Q84771）	X-RAY DIFFRACTION mmCIF provides none of the parsed experimental conditions	Resolution 2.60 Å
6	Protein heterocomplex Heteromer Protein × 20 PDB declaration: eicosameric（20） Consistent with protein copy count	Chain 4； UniProt 1–85	Not recorded	FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP1) × 5 （Q84771） FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP2) × 5 （Q84771） FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP3) × 5 （Q84771）	X-RAY DIFFRACTION mmCIF provides none of the parsed experimental conditions	Resolution 2.60 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

No other PDB entry for the same UniProt protein was found.

View Construct and Data Evidence

UniProt name	O90754_9PICO
Isoform	—
PDB entities	4
Chains and sequence ranges	Author chain 4； PDBConstruct 1–85； UniProt 1–85

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	1bbt
Deposition date deposition_date	1992-05-18
Structure title title	METHODS USED IN THE STRUCTURE DETERMINATION OF FOOT AND MOUTH DISEASE VIRUS
Keywords keywords	VIRUS, Icosahedral virus; VIRUS
Experimental Method method	X-RAY DIFFRACTION

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3. SAXS Parameters (CRYSOL theoretical calculation) 3. SAXS Parameters (CRYSOL)

Radius of gyration Rg (Guinier) rg_guinier	31.03 Å
Radius of gyration Rg (electron density) rg_electron	30.55 Å
Forward intensity I(0) i0	85964300.00
Molecular weight molecular_weight	72917.0 kDa
Excluded volume excluded_volume	91209 Å³
Envelope volume envelope_volume	127380 Å³
Hydration-shell volume shell_volume	35356 Å³
Envelope diameter envelope_diameter	110.8 Å
Shell Rg shell_rg	36.64 Å
Envelope Rg envelope_rg	31.36 Å
Shape Rg shape_rg	30.53 Å
Total Rg total_rg	31.21 Å
Total atoms total_atoms	5142
Residues n_residues	662
Spherical-harmonic order n_harmonics	20
q range q_range	— – 0.5000 Å⁻¹
Data points n_points	101
Shell type shell_type	directional
Solvent electron density solvent_density	0.3340 e/Å³
Shell contrast contrast_shell	0.0300 e/Å³
CRYSOL version crysol_version	4.1.3

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4. P(r) Distance Distribution (GNOM inversion) 4. P(r) Analysis (GNOM)

Maximum dimension Dmax dmax	104.0 Å
Rg (real space) rg_real	31.06 Å
Rg uncertainty (real space) rg_real_error	0.83 Å
I(0) (real space) i0_real	8.5960e+07
I(0) uncertainty (real space) i0_real_error	1.3300e+06
Rg (reciprocal space) rg_reciprocal	31.05 Å
I(0) (reciprocal space) i0_reciprocal	85960000.0000
Solution quality estimate total_estimate	0.8871
Solution quality rating solution_quality	GOOD a GOOD solution
P(r) peaks n_peaks	2
Primary peak position r_peak_primary	34.7 Å
Skewness Skewness skewness	0.364
Kurtosis Kurtosis kurtosis	-0.343
Angular range angular_range	— – 0.2550 Å⁻¹
Current regularization parameter α current_alpha	0.0000
Highest regularization parameter α highest_alpha	15870000.0000
Real-space data points n_real_points	52
GNOM version gnom_version	4.1.3
Quality Criteria quality_criteria	AN1: 0.000; Oscil: 0.876; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.949; Smooth: 0.953

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5. Crystallography and Experiment 5. Crystallography & Experiment

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6. Entities and Polymers Entities & Polymers (4)

Entity 1 Entity 1 polymer

Description description	FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP1)
Molecular weight formula_weight	23814.2 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	1
Atom count atom_count	5142

TTSAGESADPVTTTVENYGGETQIQRRQHTDVSFIMDRFVKVTPQNQINILDLMQVPSHTLVGGLLRASTYYFSDLEIAVKHEGDLTWVPNGAPEKALDNTTNPTAYHKAPLTRLALPYTAPHRVLATVYNGECRYSRNAVPNLRGDLQVLAQKVARTLPTSFNYGAIKATRVTELLYRMKRAETYCPRPLLAIHPTEARHKQKIVAPVKQTL

来源 Source

来源生物 organism	Foot-and-mouth disease virus
NCBI Class编号 ncbi_taxonomy_id	12110

Entity 2 Entity 2 polymer

Description description	FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP2)
Molecular weight formula_weight	24373.5 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	2

DKKTEETTLLEDRILTTRNGHTTSTTQSSVGVTYGYATAEDFVSGPNTSGLETRVVQAERFFKTHLFDWVTSDSFGRCHLLELPTDHKGVYGSLTDSYAYMRNGWDVEVTAVGNQFNGGCLLVAMVPELCSIQKRELYQLTLFPHQFINPRTNMTAHITVPFVGVNRYDQYKVHKPWTLVVMVVAPLTVNTEGAPQIKVYANIAPTNVHVAGEFPSKE

来源 Source

来源生物 organism	Foot-and-mouth disease virus
NCBI Class编号 ncbi_taxonomy_id	12110

Entity 3 Entity 3 polymer

Description description	FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP3)
Molecular weight formula_weight	23860.8 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	3

GIFPVACSDGYGGLVTTDPKTADPVYGKVFNPPRNQLPGRFTNLLDVAEACPTFLRFEGGVPYVTTKTDSDRVLAQFDMSLAAKHMSNTFLAGLAQYYTQYSGTINLHFMFTGPTDAKARYMVAYAPPGMEPPKTPEAAAHCIHAEWDTGLNSKFTFSIPYLSAADYTYTASDVAETTNVQGWVCLFQITHGKADGDALVVLASAGKDFELRLPVDARAE

来源 Source

来源生物 organism	Foot-and-mouth disease virus
NCBI Class编号 ncbi_taxonomy_id	12110

Entity 4 Entity 4 polymer

Description description	FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP4)
Molecular weight formula_weight	8778.1 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	4

GAGQSSPATGSQNQSGNTGSIINNYYMQQYQNSMDTQLGNDAISGGSNEGSTDTTSTHTTNTQNNDWFSKLASSAFSGLFGALLA

来源 Source

来源生物 organism	Foot-and-mouth disease virus
NCBI Class编号 ncbi_taxonomy_id	12110

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7. Fold Classification (SCOP + CATH) 7 domains

SCOP 2.08 (3 domains)

Domain ID domain_id	d1bbt.1
Class class	b — All beta proteins
Fold Fold fold	b.121 — Nucleoplasmin-like/VP (viral coat and capsid proteins)
Superfamily Superfamily superfamily	b.121.4 — Positive stranded ssRNA viruses
Family Family family	b.121.4.1 — Picornaviridae-like VP (VP1, VP2, VP3 and VP4)

Domain ID domain_id	d1bbt1_
Class class	b — All beta proteins
Fold Fold fold	b.121 — Nucleoplasmin-like/VP (viral coat and capsid proteins)
Superfamily Superfamily superfamily	b.121.4 — Positive stranded ssRNA viruses
Family Family family	b.121.4.1 — Picornaviridae-like VP (VP1, VP2, VP3 and VP4)

Domain ID domain_id	d1bbt3_
Class class	b — All beta proteins
Fold Fold fold	b.121 — Nucleoplasmin-like/VP (viral coat and capsid proteins)
Superfamily Superfamily superfamily	b.121.4 — Positive stranded ssRNA viruses
Family Family family	b.121.4.1 — Picornaviridae-like VP (VP1, VP2, VP3 and VP4)

CATH v4.4 (4 domains)

Domain ID domain_id	1bbt100
Class class	2 — Mainly Beta
Architecture architecture	60 — Sandwich
Topology topology	120 — Jelly Rolls
Homologous superfamily homologous superfamily	20 —

Domain ID domain_id	1bbt200
Class class	2 — Mainly Beta
Architecture architecture	60 — Sandwich
Topology topology	120 — Jelly Rolls
Homologous superfamily homologous superfamily	20 —

Domain ID domain_id	1bbt300
Class class	2 — Mainly Beta
Architecture architecture	60 — Sandwich
Topology topology	120 — Jelly Rolls
Homologous superfamily homologous superfamily	20 —

Domain ID domain_id	1bbt400
Class class	4 — Few Secondary Structures
Architecture architecture	10 — Irregular
Topology topology	90 — Foot-And-Mouth Disease Virus, subunit 4
Homologous superfamily homologous superfamily	10 — Capsid protein VP4 superfamily, Picornavirus

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8. Citations (9)

Methods used in the structure determination of foot-and-mouth disease virus.

Acta Crystallogr.,Sect.A (1993)

PMID: 8382928 · DOI: 10.1107/S0108767392005737 PRIMARY

The Three-Dimensional Structure of Foot-and-Mouth Disease Virus

New Aspects of Positive-Strand RNA Viruses (1990)

Architecture and Topography of an Aphthovirus

Semin.Virol. (1990)

Structural and Serological Evidence for a Novel Mechanism of Antigenic Variation in Foot-and-Mouth Disease Virus

Nature (1990)

Structure of Foot-and-Mouth Disease Virus

Use of X-Ray Crystallography in the Design of Antiviral Agents (1990)

The Structure of Foot-and-Mouth Disease Virus: Implications for its Physical and Biological Properties

Vet.Microbiol. (1990)

The Three-Dimensional Structure of Foot-and-Mouth Disease Virus at 2.9 Angstroms Resolution

Nature (1989)

Implications of the Three-Dimensional Structure of Foot-and-Mouth Disease Virus for its Antigenicity and Cell Attachment

Vaccines 89: Modern Approaches to New Vaccines Including Prevention of Aids (1989)

Crystallization and Preliminary X-Ray Diffraction Analysis of Foot-and-Mouth Disease Virus

J.Mol.Biol. (1987)

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Unit-cell length a length_a	345.000 Å
Unit-cell length b length_b	345.000 Å
Unit-cell length c length_c	345.000 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	120

Space group space_group	I 2 3
Space-group number int_tables_number	197
Crystal system crystal_system	—

Resolution resolution	2.600 Å
Low-resolution limit resolution_low	— Å
R factor r_factor	0.1690
R_work r_work	0.1690
R_free r_free	—

fit	/app/data/saxs_computation/bb/1bbt/1bbt.fit
pddf	/app/data/pr_computation/bb/1bbt/1bbt.pr.out
profile	/app/data/saxs_computation/bb/1bbt/1bbt.dat

METHODS USED IN THE STRUCTURE DETERMINATION OF FOOT AND MOUTH DISEASE VIRUS

1. Protein Identity and Related Structures Protein Identity & Related Structures

FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP1)

State in the Current Structure

Other States of the Same Protein in the Database

FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP4)

State in the Current Structure

Other States of the Same Protein in the Database

SAXS scattering curve SAXS Profile

P(r) Distance Distribution P(r) Distribution

2. Structure Basics 2. Structure Basics

3. SAXS Parameters (CRYSOL theoretical calculation) 3. SAXS Parameters (CRYSOL)

4. P(r) Distance Distribution (GNOM inversion) 4. P(r) Analysis (GNOM)

5. Crystallography and Experiment 5. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

6. Entities and Polymers Entities & Polymers (4)

Entity 1 Entity 1 polymer

Polymer Polymer

来源 Source

Entity 2 Entity 2 polymer

Polymer Polymer

来源 Source

Entity 3 Entity 3 polymer

Polymer Polymer

来源 Source

Entity 4 Entity 4 polymer

Polymer Polymer

来源 Source

7. Fold Classification (SCOP + CATH) 7 domains

SCOP 2.08 (3 domains)

CATH v4.4 (4 domains)

8. Citations (9)

9. Files and Curves (10)

Files (7)

Curves (3)