Homo sapiens
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein monomer | Monomer | Protein 1 | 4-[3-METHYLSULFANYLANILINO]-6,7-DIMETHOXYQUINAZOLINE × 1 water × 1 | Consistent with protein count |
| UniProt name | MK14_HUMAN |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 1–360； UniProt 1–360 |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
| Entry ID entry_id | 1di9 |
| Deposition date deposition_date | 1999-11-29 |
| Structure title title | THE STRUCTURE OF P38 MITOGEN-ACTIVATED PROTEIN KINASE IN COMPLEX WITH 4-[3-METHYLSULFANYLANILINO]-6,7-DIMETHOXYQUINAZOLINE |
| Keywords keywords | SERINE/THREONINE PROTEIN KINASE, MAP KINASE, P38, TRANSFERASE; TRANSFERASE |
| Experimental Method method | X-RAY DIFFRACTION |
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 22.53 Å |
| Rg (electron density) | 21.58 Å |
| Total Rg | 22.43 Å |
| Atom count | 2798 |
| Residues | 348 |
| Excluded volume | 49992 ų |
| Maximum q | 0.500 Å⁻¹ |
| Domain ID domain_id | d1di9a_ |
| Class class | d — Alpha and beta proteins (a+b) |
| Fold Fold fold | d.144 — Protein kinase-like (PK-like) |
| Superfamily Superfamily superfamily | d.144.1 — Protein kinase-like (PK-like) |
| Family Family family | d.144.1.7 — Protein kinases, catalytic subunit |
| Domain ID domain_id | 1di9A01 |
| Class class | 3 — Alpha Beta |
| Architecture architecture | 30 — 2-Layer Sandwich |
| Topology topology | 200 — Phosphorylase Kinase; domain 1 |
| Homologous superfamily homologous superfamily | 20 — Phosphorylase Kinase; domain 1 |
| Domain ID domain_id | 1di9A02 |
| Class class | 1 — Mainly Alpha |
| Architecture architecture | 10 — Orthogonal Bundle |
| Topology topology | 510 — Transferase(Phosphotransferase); domain 1 |
| Homologous superfamily homologous superfamily | 10 — Transferase(Phosphotransferase) domain 1 |