COMPLEX OF CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH HMG-COA

Method: X-RAY DIFFRACTION D_max: 120.6 Å Quality: GOOD

SAXS Profile

P(r) Distribution

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1. Structure Basics

entry_id	1dq9
deposition_date	1999-12-30
title	COMPLEX OF CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH HMG-COA
keywords	OXIDOREDUCTASE, CHOLESTEROL BIOSYNTHESIS, HMG-COA, NADPH; OXIDOREDUCTASE
method	X-RAY DIFFRACTION

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	33.82 Å
rg_electron	33.39 Å
i0	509941000.00
molecular_weight	177390.0 kDa
excluded_volume	220090 Å³
envelope_volume	256680 Å³
shell_volume	60476 Å³
envelope_diameter	130.7 Å
shell_rg	42.13 Å
envelope_rg	34.12 Å
shape_rg	33.43 Å
total_rg	33.83 Å
total_atoms	12351
n_residues	1630
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	120.6 Å
rg_real	33.74 Å
rg_real_error	0.82 Å
i0_real	5.0990e+08
i0_real_error	7.1400e+06
rg_reciprocal	33.79 Å
i0_reciprocal	510000000.0000
total_estimate	0.8384
solution_quality	GOOD a GOOD solution
n_peaks	2
r_peak_primary	41.1 Å
skewness	0.364
kurtosis	-0.076
angular_range	— – 0.2350 Å⁻¹
current_alpha	0.0000
highest_alpha	185400000.0000
n_real_points	48
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.649; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.989; Smooth: 0.960

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4. Crystallography & Experiment

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5. Entities & Polymer Info (2)

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6. Citations (1)

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length_a	74.580 Å
length_b	171.200 Å
length_c	80.370 Å
angle_alpha	90.00 °
angle_beta	116.59 °
angle_gamma	90.00 °
z_pdb	8

space_group	P 1 21 1
int_tables_number	4
crystal_system	—

resolution	2.800 Å
resolution_low	25.000 Å
r_factor	0.2070
r_work	0.2070
r_free	0.2470

description	PROTEIN (HMG-COA REDUCTASE)
formula_weight	50021.5 kDa
ec_number	1.1.1.34
mutation	YES
src_method	man
entity_count	4

type	polypeptide(L)
strand_id	A,B,C,D
atom_count	12351

COMPLEX OF CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH HMG-COA

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

Refinement

Diffraction

5. Entities & Polymer Info (2)

Entity 1 polymer

Polymer

Source

Entity 2 non-polymer

6. Citations (1)

7. Files & Curves (10)

Files (7)

Curves (3)

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Escherichia coli

description	3-HYDROXY-3-METHYLGLUTARYL-COENZYME A
formula_weight	906.6 kDa
src_method	syn
entity_count	4

fit	/app/data/saxs_computation/dq/1dq9/1dq9.fit
pddf	/app/data/pr_computation/dq/1dq9/1dq9.pr.out
profile	/app/data/saxs_computation/dq/1dq9/1dq9.dat