LATENT FORM OF PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1)

Method: X-RAY DIFFRACTION D_max: 70.1 Å Quality: REASONABLE

SAXS Profile

P(r) Distribution

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1. Structure Basics

entry_id	1dvn
deposition_date	2000-01-21
title	LATENT FORM OF PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1)
keywords	SERPIN, PAI-1, INHIBITOR, BLOOD CLOTTING; BLOOD CLOTTING
method	X-RAY DIFFRACTION

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	22.05 Å
rg_electron	20.87 Å
i0	29709800.00
molecular_weight	42768.0 kDa
excluded_volume	53894 Å³
envelope_volume	60612 Å³
shell_volume	23962 Å³
envelope_diameter	71.0 Å
shell_rg	27.83 Å
envelope_rg	21.19 Å
shape_rg	20.88 Å
total_rg	21.72 Å
total_atoms	3013
n_residues	379
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	70.1 Å
rg_real	21.96 Å
rg_real_error	0.38 Å
i0_real	2.9710e+07
i0_real_error	3.8320e+05
rg_reciprocal	21.98 Å
i0_reciprocal	29710000.0000
total_estimate	0.7227
solution_quality	REASONABLE a REASONABLE solution
n_peaks	2
r_peak_primary	27.2 Å
skewness	0.277
kurtosis	-0.333
angular_range	— – 0.3600 Å⁻¹
current_alpha	0.0000
highest_alpha	6197000.0000
n_real_points	68
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.869; Stabil: 1.000; Sysdev: 0.262; Positv: 1.000; Valcen: 1.000; Smooth: 0.998

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4. Crystallography & Experiment

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5. Entities & Polymer Info (2)

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6. Citations (1)

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length_a	154.581 Å
length_b	46.697 Å
length_c	61.966 Å
angle_alpha	90.00 °
angle_beta	107.11 °
angle_gamma	90.00 °
z_pdb	4

space_group	C 1 2 1
int_tables_number	5
crystal_system	—

resolution	2.100 Å
resolution_low	30.000 Å
r_factor	0.2360
r_work	0.2360
r_free	0.2890

description	PLASMINOGEN ACTIVATOR INHIBITOR-1
formula_weight	42819.1 kDa
mutation	N150H, K154T, Q319L, M354I
src_method	man
entity_count	1

type	polypeptide(L)
strand_id	A
atom_count	3326

LATENT FORM OF PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1)

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

Refinement

Diffraction

5. Entities & Polymer Info (2)

Entity 1 polymer

Polymer

Source

Entity 2 water

6. Citations (1)

7. Files & Curves (10)

Files (7)

Curves (3)

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Escherichia coli

description	water
formula_weight	18.0 kDa
src_method	nat
entity_count	313

fit	/app/data/saxs_computation/dv/1dvn/1dvn.fit
pddf	/app/data/pr_computation/dv/1dvn/1dvn.pr.out
profile	/app/data/saxs_computation/dv/1dvn/1dvn.dat