1fj1

LYME DISEASE ANTIGEN OSPA IN COMPLEX WITH NEUTRALIZING ANTIBODY FAB LA-2

Method: X-RAY DIFFRACTION Dmax: 183.6 Å Quality: REASONABLE

SAXS 散射曲线 SAXS Profile

SAXS profile for 1fj1

P(r) 距离分布 P(r) Distribution

P(r) distribution for 1fj1
下载 Download

1. 结构基本信息 1. Structure Basics

条目编号 entry_id1fj1
沉积日期 deposition_date2000-08-07
结构标题 titleLYME DISEASE ANTIGEN OSPA IN COMPLEX WITH NEUTRALIZING ANTIBODY FAB LA-2
关键词 keywordsOSPA, LYME DISEASE, ANTIBODY FAB FRAGMENT, NEUTRALIZING EPITOPE, IMMUNE SYSTEM; IMMUNE SYSTEM
实验方法 methodX-RAY DIFFRACTION

2. SAXS 参数 (CRYSOL 理论计算) 2. SAXS Parameters (CRYSOL)

回转半径 Rg (Guinier) rg_guinier43.63
回转半径 Rg (电子) rg_electron44.78
零角强度 I(0) i0333510000.00
分子量 molecular_weight146410.0 kDa
排除体积 excluded_volume182570 ų
包络体积 envelope_volume260380 ų
水化壳体积 shell_volume54173 ų
包络直径 envelope_diameter196.1
壳层 Rg shell_rg42.89
包络 Rg envelope_rg46.71
形状 Rg shape_rg44.69
总 Rg total_rg44.99
总原子数 total_atoms10284
残基数 n_residues1354
球谐函数阶数 n_harmonics20
q 范围 q_range— – 0.5000 −1
数据点数 n_points101
壳层类型 shell_typedirectional
溶剂电子密度 solvent_density0.3340 e/ų
壳层衬度 contrast_shell0.0300 e/ų
CRYSOL 版本 crysol_version4.1.3

3. P(r) 距离分布 (GNOM 反演) 3. P(r) Analysis (GNOM)

最大尺寸 Dmax dmax183.6
Rg (实空间) rg_real44.49
Rg 误差 (实空间) rg_real_error3.34
I(0) (实空间) i0_real3.3350e+08
I(0) 误差 (实空间) i0_real_error6.5400e+06
Rg (倒空间) rg_reciprocal43.63
I(0) (倒空间) i0_reciprocal333200000.0000
解质量估计 total_estimate0.6868
解质量评级 solution_quality REASONABLE a REASONABLE solution
P(r) 峰数 n_peaks3
主峰位置 r_peak_primary45.9
偏度 Skewness skewness0.943
峰度 Kurtosis kurtosis0.931
角度范围 angular_range— – 0.1800 −1
当前正则化参数 α current_alpha0.0000
最高正则化参数 α highest_alpha29230000.0000
实空间数据点数 n_real_points37
GNOM 版本 gnom_version4.1.3
质量判据 quality_criteria AN1: 0.000; Oscil: 0.238; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.333; Smooth: 0.876

4. 晶体学与实验 4. Crystallography & Experiment

5. 实体与聚合体信息 (4)

6. 折叠分类 (SCOP + CATH) 22 domains

SCOP 2.08 (10 domains)

结构域编号 domain_idd1fj1a1
类 Class classb — All beta proteins
折叠类型 Fold foldb.1 — Immunoglobulin-like beta-sandwich
超家族 Superfamily superfamilyb.1.1 — Immunoglobulin
家族 Family familyb.1.1.1 — V set domains (antibody variable domain-like)
结构域编号 domain_idd1fj1a2
类 Class classb — All beta proteins
折叠类型 Fold foldb.1 — Immunoglobulin-like beta-sandwich
超家族 Superfamily superfamilyb.1.1 — Immunoglobulin
家族 Family familyb.1.1.2 — C1 set domains (antibody constant domain-like)
结构域编号 domain_idd1fj1b1
类 Class classb — All beta proteins
折叠类型 Fold foldb.1 — Immunoglobulin-like beta-sandwich
超家族 Superfamily superfamilyb.1.1 — Immunoglobulin
家族 Family familyb.1.1.1 — V set domains (antibody variable domain-like)
结构域编号 domain_idd1fj1b2
类 Class classb — All beta proteins
折叠类型 Fold foldb.1 — Immunoglobulin-like beta-sandwich
超家族 Superfamily superfamilyb.1.1 — Immunoglobulin
家族 Family familyb.1.1.2 — C1 set domains (antibody constant domain-like)
结构域编号 domain_idd1fj1c1
类 Class classb — All beta proteins
折叠类型 Fold foldb.1 — Immunoglobulin-like beta-sandwich
超家族 Superfamily superfamilyb.1.1 — Immunoglobulin
家族 Family familyb.1.1.1 — V set domains (antibody variable domain-like)
结构域编号 domain_idd1fj1c2
类 Class classb — All beta proteins
折叠类型 Fold foldb.1 — Immunoglobulin-like beta-sandwich
超家族 Superfamily superfamilyb.1.1 — Immunoglobulin
家族 Family familyb.1.1.2 — C1 set domains (antibody constant domain-like)
结构域编号 domain_idd1fj1d1
类 Class classb — All beta proteins
折叠类型 Fold foldb.1 — Immunoglobulin-like beta-sandwich
超家族 Superfamily superfamilyb.1.1 — Immunoglobulin
家族 Family familyb.1.1.1 — V set domains (antibody variable domain-like)
结构域编号 domain_idd1fj1d2
类 Class classb — All beta proteins
折叠类型 Fold foldb.1 — Immunoglobulin-like beta-sandwich
超家族 Superfamily superfamilyb.1.1 — Immunoglobulin
家族 Family familyb.1.1.2 — C1 set domains (antibody constant domain-like)
结构域编号 domain_idd1fj1e_
类 Class classb — All beta proteins
折叠类型 Fold foldb.76 — open-sided beta-meander
超家族 Superfamily superfamilyb.76.1 — Outer surface protein
家族 Family familyb.76.1.1 — Outer surface protein
结构域编号 domain_idd1fj1f_
类 Class classb — All beta proteins
折叠类型 Fold foldb.76 — open-sided beta-meander
超家族 Superfamily superfamilyb.76.1 — Outer surface protein
家族 Family familyb.76.1.1 — Outer surface protein

CATH v4.4 (12 domains)

结构域编号 domain_id1fj1A01
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily10 — Immunoglobulins
结构域编号 domain_id1fj1A02
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily10 — Immunoglobulins
结构域编号 domain_id1fj1B01
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily10 — Immunoglobulins
结构域编号 domain_id1fj1B02
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily10 — Immunoglobulins
结构域编号 domain_id1fj1C01
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily10 — Immunoglobulins
结构域编号 domain_id1fj1C02
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily10 — Immunoglobulins
结构域编号 domain_id1fj1D01
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily10 — Immunoglobulins
结构域编号 domain_id1fj1D02
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily10 — Immunoglobulins
结构域编号 domain_id1fj1E01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology128 — Lipocalin
同源超家族 H-superfamily homologous superfamily160 — C1 set domains (antibody constant domain-like)
结构域编号 domain_id1fj1E02
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology930 — Outer Surface Protein A; domain 3
同源超家族 H-superfamily homologous superfamily1
结构域编号 domain_id1fj1F01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology128 — Lipocalin
同源超家族 H-superfamily homologous superfamily160 — C1 set domains (antibody constant domain-like)
结构域编号 domain_id1fj1F02
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology930 — Outer Surface Protein A; domain 3
同源超家族 H-superfamily homologous superfamily1

7. 引用文献 (1)

8. 文件与曲线 (10)