1fui

L-FUCOSE ISOMERASE FROM ESCHERICHIA COLI

Method: X-RAY DIFFRACTION

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1. Protein Identity and Related Structures Protein Identity & Related Structures

L-FUCOSE ISOMERASE

Escherichia coli

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein homooligomer	Homooligomer	Protein 3	MANGANESE (II) ION × 3 SULFATE ION × 1 FUCITOL × 3 water × 3	Consistent with protein count
2	Protein homooligomer	Homooligomer	Protein 3	MANGANESE (II) ION × 2 SULFATE ION × 1 FUCITOL × 3 water × 3	Consistent with protein count
3	Protein homooligomer	Homooligomer	Protein 6	MANGANESE (II) ION × 5 SULFATE ION × 2 FUCITOL × 6 water × 6	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	FUCI_ECOLI
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 1–591； UniProt 1–591 Author chain B； PDBConstruct 1–591； UniProt 1–591 Author chain C； PDBConstruct 1–591； UniProt 1–591 Author chain D； PDBConstruct 1–591； UniProt 1–591 Author chain E； PDBConstruct 1–591； UniProt 1–591 Author chain F； PDBConstruct 1–591； UniProt 1–591

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	1fui
Deposition date deposition_date	1997-04-14
Structure title title	L-FUCOSE ISOMERASE FROM ESCHERICHIA COLI
Keywords keywords	ISOMERASE, KETOL ISOMERASE, FUCOSE METABOLISM, L-FUCOSE TO L-FUCULOSE CONVERSION; ISOMERASE
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1fui__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1fui__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

1fui__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	39.72 Å
Rg (electron density)	38.90 Å
Total Rg	39.29 Å
Atom count	13712
Residues	1773
Excluded volume	242020 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`1fui__assembly_1__model_1`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	1	`1fui__assembly_2__model_1`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
3	1	`1fui__assembly_3__model_1`	hexameric （6）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (5)

Entity 1 Entity 1 polymer

Description description	L-FUCOSE ISOMERASE
Molecular weight formula_weight	65049.5 kDa
EC 编号 ec_number	5.3.1.3
Source method src_method	man
Copy count entity_count	6

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,B,C,D,E,F
Atom count atom_count	28295

MKKISLPKIGIRPVIDGRRMGVRESLEEQTMNMAKATAALLTEKLRHACGAAVECVISDTCIAGMAEAAACEEKFSSQNVGLTITVTPCWCYGSETIDMDPTRPKAIWGFNGTERPGAVYLAAALAAHSQKGIPAFSIYGHDVQDADDTSIPADVEEKLLRFARAGLAVASMKGKSYLSLGGVSMGIAGSIVDHNFFESWLGMKVQAVDMTELRRRIDQKIYDEAELEMALAWADKNFRYGEDENNKQYQRNAEQSRAVLRESLLMAMCIRDMMQGNSKLADIGRVEESLGYNAIAAGFQGQRHWTDQYPNGDTAEAILNSSFDWNGVREPFVVATENDSLNGVAMLMGHQLTGTAQVFADVRTYWSPEAIERVTGHKLDGLAEHGIIHLINSGSAALDGSCKQRDSEGNPTMKPHWEISQQEADACLAATEWCPAIHEYFRGGGYSSRFLTEGGVPFTMTRVNIIKGLGPVLQIAEGWSVELPKDVHDILNKRTNSTWPTTWFAPRLTGKGPFTDVYSVMANWGANHGVLTIGHVGADFITLASMLRIPVCMHNVEETKVYRPSAWAAHGMDIEGQDYRACQNYGPLYKR

Source Source

Source organism organism	Escherichia coli
NCBI taxonomy ID ncbi_taxonomy_id	83333
Host organism host_organism	Escherichia coli K12

Entity 2 Entity 2 non-polymer

Description description	MANGANESE (II) ION
Molecular weight formula_weight	54.9 kDa
Source method src_method	syn
Copy count entity_count	5

Entity 3 Entity 3 non-polymer

Description description	SULFATE ION
Molecular weight formula_weight	96.1 kDa
Source method src_method	syn
Copy count entity_count	2

Entity 4 Entity 4 non-polymer

Description description	FUCITOL
Molecular weight formula_weight	166.2 kDa
Source method src_method	syn
Copy count entity_count	6

Entity 5 Entity 5 water

Description description	water
Molecular weight formula_weight	18.0 kDa
Source method src_method	nat
Copy count entity_count	872

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6. Fold Classification (SCOP + CATH) 30 domains

SCOP 2.08 (12 domains)

Domain ID domain_id	d1fuia1
Class class	b — All beta proteins
Fold Fold fold	b.43 — Reductase/isomerase/elongation factor common domain
Superfamily Superfamily superfamily	b.43.2 — FucI/AraA C-terminal domain-like
Family Family family	b.43.2.1 — L-fucose isomerase, C-terminal domain

Domain ID domain_id	d1fuia2
Class class	c — Alpha and beta proteins (a/b)
Fold Fold fold	c.85 — FucI/AraA N-terminal and middle domains
Superfamily Superfamily superfamily	c.85.1 — FucI/AraA N-terminal and middle domains
Family Family family	c.85.1.1 — L-fucose isomerase, N-terminal and second domains

Domain ID domain_id	d1fuib1
Class class	b — All beta proteins
Fold Fold fold	b.43 — Reductase/isomerase/elongation factor common domain
Superfamily Superfamily superfamily	b.43.2 — FucI/AraA C-terminal domain-like
Family Family family	b.43.2.1 — L-fucose isomerase, C-terminal domain

Domain ID domain_id	d1fuib2
Class class	c — Alpha and beta proteins (a/b)
Fold Fold fold	c.85 — FucI/AraA N-terminal and middle domains
Superfamily Superfamily superfamily	c.85.1 — FucI/AraA N-terminal and middle domains
Family Family family	c.85.1.1 — L-fucose isomerase, N-terminal and second domains

Domain ID domain_id	d1fuic1
Class class	b — All beta proteins
Fold Fold fold	b.43 — Reductase/isomerase/elongation factor common domain
Superfamily Superfamily superfamily	b.43.2 — FucI/AraA C-terminal domain-like
Family Family family	b.43.2.1 — L-fucose isomerase, C-terminal domain

Domain ID domain_id	d1fuic2
Class class	c — Alpha and beta proteins (a/b)
Fold Fold fold	c.85 — FucI/AraA N-terminal and middle domains
Superfamily Superfamily superfamily	c.85.1 — FucI/AraA N-terminal and middle domains
Family Family family	c.85.1.1 — L-fucose isomerase, N-terminal and second domains

Domain ID domain_id	d1fuid1
Class class	b — All beta proteins
Fold Fold fold	b.43 — Reductase/isomerase/elongation factor common domain
Superfamily Superfamily superfamily	b.43.2 — FucI/AraA C-terminal domain-like
Family Family family	b.43.2.1 — L-fucose isomerase, C-terminal domain

Domain ID domain_id	d1fuid2
Class class	c — Alpha and beta proteins (a/b)
Fold Fold fold	c.85 — FucI/AraA N-terminal and middle domains
Superfamily Superfamily superfamily	c.85.1 — FucI/AraA N-terminal and middle domains
Family Family family	c.85.1.1 — L-fucose isomerase, N-terminal and second domains

Domain ID domain_id	d1fuie1
Class class	b — All beta proteins
Fold Fold fold	b.43 — Reductase/isomerase/elongation factor common domain
Superfamily Superfamily superfamily	b.43.2 — FucI/AraA C-terminal domain-like
Family Family family	b.43.2.1 — L-fucose isomerase, C-terminal domain

Domain ID domain_id	d1fuie2
Class class	c — Alpha and beta proteins (a/b)
Fold Fold fold	c.85 — FucI/AraA N-terminal and middle domains
Superfamily Superfamily superfamily	c.85.1 — FucI/AraA N-terminal and middle domains
Family Family family	c.85.1.1 — L-fucose isomerase, N-terminal and second domains

Domain ID domain_id	d1fuif1
Class class	b — All beta proteins
Fold Fold fold	b.43 — Reductase/isomerase/elongation factor common domain
Superfamily Superfamily superfamily	b.43.2 — FucI/AraA C-terminal domain-like
Family Family family	b.43.2.1 — L-fucose isomerase, C-terminal domain

Domain ID domain_id	d1fuif2
Class class	c — Alpha and beta proteins (a/b)
Fold Fold fold	c.85 — FucI/AraA N-terminal and middle domains
Superfamily Superfamily superfamily	c.85.1 — FucI/AraA N-terminal and middle domains
Family Family family	c.85.1.1 — L-fucose isomerase, N-terminal and second domains

CATH v4.4 (18 domains)

Domain ID domain_id	1fuiA01
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	50 — Rossmann fold
Homologous superfamily homologous superfamily	1070 —

Domain ID domain_id	1fuiA02
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	275 — L-fucose Isomerase; Chain A, domain 2
Homologous superfamily homologous superfamily	10 — L-fucose Isomerase; Chain A, domain 2

Domain ID domain_id	1fuiA03
Class class	3 — Alpha Beta
Architecture architecture	20 — Alpha-Beta Barrel
Topology topology	14 — L-fucose Isomerase; Chain A, domain 3
Homologous superfamily homologous superfamily	10 — L-fucose/L-arabinose isomerase, C-terminal

Domain ID domain_id	1fuiB01
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	50 — Rossmann fold
Homologous superfamily homologous superfamily	1070 —

Domain ID domain_id	1fuiB02
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	275 — L-fucose Isomerase; Chain A, domain 2
Homologous superfamily homologous superfamily	10 — L-fucose Isomerase; Chain A, domain 2

Domain ID domain_id	1fuiB03
Class class	3 — Alpha Beta
Architecture architecture	20 — Alpha-Beta Barrel
Topology topology	14 — L-fucose Isomerase; Chain A, domain 3
Homologous superfamily homologous superfamily	10 — L-fucose/L-arabinose isomerase, C-terminal

Domain ID domain_id	1fuiC01
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	50 — Rossmann fold
Homologous superfamily homologous superfamily	1070 —

Domain ID domain_id	1fuiC02
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	275 — L-fucose Isomerase; Chain A, domain 2
Homologous superfamily homologous superfamily	10 — L-fucose Isomerase; Chain A, domain 2

Domain ID domain_id	1fuiC03
Class class	3 — Alpha Beta
Architecture architecture	20 — Alpha-Beta Barrel
Topology topology	14 — L-fucose Isomerase; Chain A, domain 3
Homologous superfamily homologous superfamily	10 — L-fucose/L-arabinose isomerase, C-terminal

Domain ID domain_id	1fuiD01
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	50 — Rossmann fold
Homologous superfamily homologous superfamily	1070 —

Domain ID domain_id	1fuiD02
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	275 — L-fucose Isomerase; Chain A, domain 2
Homologous superfamily homologous superfamily	10 — L-fucose Isomerase; Chain A, domain 2

Domain ID domain_id	1fuiD03
Class class	3 — Alpha Beta
Architecture architecture	20 — Alpha-Beta Barrel
Topology topology	14 — L-fucose Isomerase; Chain A, domain 3
Homologous superfamily homologous superfamily	10 — L-fucose/L-arabinose isomerase, C-terminal

Domain ID domain_id	1fuiE01
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	50 — Rossmann fold
Homologous superfamily homologous superfamily	1070 —

Domain ID domain_id	1fuiE02
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	275 — L-fucose Isomerase; Chain A, domain 2
Homologous superfamily homologous superfamily	10 — L-fucose Isomerase; Chain A, domain 2

Domain ID domain_id	1fuiE03
Class class	3 — Alpha Beta
Architecture architecture	20 — Alpha-Beta Barrel
Topology topology	14 — L-fucose Isomerase; Chain A, domain 3
Homologous superfamily homologous superfamily	10 — L-fucose/L-arabinose isomerase, C-terminal

Domain ID domain_id	1fuiF01
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	50 — Rossmann fold
Homologous superfamily homologous superfamily	1070 —

Domain ID domain_id	1fuiF02
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	275 — L-fucose Isomerase; Chain A, domain 2
Homologous superfamily homologous superfamily	10 — L-fucose Isomerase; Chain A, domain 2

Domain ID domain_id	1fuiF03
Class class	3 — Alpha Beta
Architecture architecture	20 — Alpha-Beta Barrel
Topology topology	14 — L-fucose Isomerase; Chain A, domain 3
Homologous superfamily homologous superfamily	10 — L-fucose/L-arabinose isomerase, C-terminal

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Unit-cell length a length_a	127.300 Å
Unit-cell length b length_b	128.300 Å
Unit-cell length c length_c	239.400 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	24

Space group space_group	P 21 21 21
Space-group number int_tables_number	19
Crystal system crystal_system	—

Resolution resolution	2.500 Å
Low-resolution limit resolution_low	20.000 Å
R factor r_factor	0.1620
R_work r_work	0.1620
R_free r_free	0.2090

L-FUCOSE ISOMERASE FROM ESCHERICHIA COLI

1. Protein Identity and Related Structures Protein Identity & Related Structures

L-FUCOSE ISOMERASE

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

1fui__assembly_1__model_1

1fui__assembly_1__model_1 | I(q)

1fui__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (5)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 non-polymer

Entity 3 Entity 3 non-polymer

Entity 4 Entity 4 non-polymer

Entity 5 Entity 5 water

6. Fold Classification (SCOP + CATH) 30 domains

SCOP 2.08 (12 domains)

CATH v4.4 (18 domains)

7. Citations (1)

L-FUCOSE ISOMERASE FROM ESCHERICHIA COLI

1. Protein Identity and Related Structures Protein Identity & Related Structures

L-FUCOSE ISOMERASE

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

1fui__assembly_1__model_1

1fui__assembly_1__model_1 | I(q)

1fui__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (5)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 non-polymer

Entity 3 Entity 3 non-polymer

Entity 4 Entity 4 non-polymer

Entity 5 Entity 5 water

6. Fold Classification (SCOP + CATH) 30 domains

SCOP 2.08 (12 domains)

CATH v4.4 (18 domains)

7. Citations (1)