1gku

Reverse gyrase from Archaeoglobus fulgidus

Method: X-RAY DIFFRACTION Dmax: 128.9 Å Quality: GOOD

SAXS 散射曲线 SAXS Profile

SAXS profile for 1gku

P(r) 距离分布 P(r) Distribution

P(r) distribution for 1gku
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1. 结构基本信息 1. Structure Basics

条目编号 entry_id1gku
沉积日期 deposition_date2001-08-21
结构标题 titleReverse gyrase from Archaeoglobus fulgidus
关键词 keywordsTOPOISOMERASE, DNA SUPERCOILING, ARCHAEA, HELICASE; TOPOISOMERASE
实验方法 methodX-RAY DIFFRACTION

2. SAXS 参数 (CRYSOL 理论计算) 2. SAXS Parameters (CRYSOL)

回转半径 Rg (Guinier) rg_guinier36.08
回转半径 Rg (电子) rg_electron35.70
零角强度 I(0) i0197946000.00
分子量 molecular_weight115580.0 kDa
排除体积 excluded_volume145930 ų
包络体积 envelope_volume192450 ų
水化壳体积 shell_volume45767 ų
包络直径 envelope_diameter138.0
壳层 Rg shell_rg41.24
包络 Rg envelope_rg35.60
形状 Rg shape_rg35.71
总 Rg total_rg36.08
总原子数 total_atoms8151
残基数 n_residues1011
球谐函数阶数 n_harmonics20
q 范围 q_range— – 0.5000 −1
数据点数 n_points101
壳层类型 shell_typedirectional
溶剂电子密度 solvent_density0.3340 e/ų
壳层衬度 contrast_shell0.0300 e/ų
CRYSOL 版本 crysol_version4.1.3

3. P(r) 距离分布 (GNOM 反演) 3. P(r) Analysis (GNOM)

最大尺寸 Dmax dmax128.9
Rg (实空间) rg_real36.12
Rg 误差 (实空间) rg_real_error1.22
I(0) (实空间) i0_real1.9790e+08
I(0) 误差 (实空间) i0_real_error3.3130e+06
Rg (倒空间) rg_reciprocal36.09
I(0) (倒空间) i0_reciprocal197900000.0000
解质量估计 total_estimate0.8634
解质量评级 solution_quality GOOD a GOOD solution
P(r) 峰数 n_peaks2
主峰位置 r_peak_primary43.9
偏度 Skewness skewness0.387
峰度 Kurtosis kurtosis-0.159
角度范围 angular_range— – 0.2200 −1
当前正则化参数 α current_alpha0.0000
最高正则化参数 α highest_alpha30350000.0000
实空间数据点数 n_real_points45
GNOM 版本 gnom_version4.1.3
质量判据 quality_criteria AN1: 0.000; Oscil: 0.773; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.943; Smooth: 0.957

4. 晶体学与实验 4. Crystallography & Experiment

5. 实体与聚合体信息 (2)

6. 折叠分类 (SCOP + CATH) 12 domains

SCOP 2.08 (4 domains)

结构域编号 domain_idd1gkub1
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.16 — Helicase-like domain of reverse gyrase
结构域编号 domain_idd1gkub2
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.16 — Helicase-like domain of reverse gyrase
结构域编号 domain_idd1gkub3
类 Class classe — Multi-domain proteins (alpha and beta)
折叠类型 Fold folde.10 — Prokaryotic type I DNA topoisomerase
超家族 Superfamily superfamilye.10.1 — Prokaryotic type I DNA topoisomerase
家族 Family familye.10.1.1 — Prokaryotic type I DNA topoisomerase
结构域编号 domain_idd1gkub4
类 Class classl — Artifacts
折叠类型 Fold foldl.1 — Tags
超家族 Superfamily superfamilyl.1.1 — Tags
家族 Family familyl.1.1.1 — Tags

CATH v4.4 (8 domains)

结构域编号 domain_id1gkuB01
类 Class class2 — Mainly Beta
架构 Architecture architecture20 — Single Sheet
拓扑 Topology topology20 — Anthopleurin-A
同源超家族 H-superfamily homologous superfamily30 — reverse gyrase domain
结构域编号 domain_id1gkuB02
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id1gkuB03
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id1gkuB04
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology56 — Phenylalanyl-tRNA Synthetase; Chain B, domain 1
同源超家族 H-superfamily homologous superfamily120
结构域编号 domain_id1gkuB05
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily140
结构域编号 domain_id1gkuB06
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology460 — Topoisomerase I; domain 2
同源超家族 H-superfamily homologous superfamily10 — Topoisomerase I, domain 2
结构域编号 domain_id1gkuB07
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology510 — EV matrix protein fold
同源超家族 H-superfamily homologous superfamily20
结构域编号 domain_id1gkuB08
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology290 — Topoisomerase I; domain 4
同源超家族 H-superfamily homologous superfamily10 — Topoisomerase I, domain 4

7. 引用文献 (1)

8. 文件与曲线 (10)